These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
140 related articles for article (PubMed ID: 34619972)
1. Tumor-associated macrophages increase COX-2 expression promoting endocrine resistance in breast cancer via the PI3K/Akt/mTOR pathway. Qin Q; Ji H; Li D; Zhang H; Zhang Z; Zhang Q Neoplasma; 2021 Sep; 68(5):938-946. PubMed ID: 34619972 [TBL] [Abstract][Full Text] [Related]
2. Tumor-associated macrophages secrete CC-chemokine ligand 2 and induce tamoxifen resistance by activating PI3K/Akt/mTOR in breast cancer. Li D; Ji H; Niu X; Yin L; Wang Y; Gu Y; Wang J; Zhou X; Zhang H; Zhang Q Cancer Sci; 2020 Jan; 111(1):47-58. PubMed ID: 31710162 [TBL] [Abstract][Full Text] [Related]
3. Cyclooxygenase-2 in tumor-associated macrophages promotes breast cancer cell survival by triggering a positive-feedback loop between macrophages and cancer cells. Li H; Yang B; Huang J; Lin Y; Xiang T; Wan J; Li H; Chouaib S; Ren G Oncotarget; 2015 Oct; 6(30):29637-50. PubMed ID: 26359357 [TBL] [Abstract][Full Text] [Related]
4. Targeting the PI3K/AKT/mTOR pathway in estrogen receptor-positive breast cancer. Ciruelos Gil EM Cancer Treat Rev; 2014 Aug; 40(7):862-71. PubMed ID: 24774538 [TBL] [Abstract][Full Text] [Related]
5. Overcoming endocrine resistance due to reduced PTEN levels in estrogen receptor-positive breast cancer by co-targeting mammalian target of rapamycin, protein kinase B, or mitogen-activated protein kinase kinase. Fu X; Creighton CJ; Biswal NC; Kumar V; Shea M; Herrera S; Contreras A; Gutierrez C; Wang T; Nanda S; Giuliano M; Morrison G; Nardone A; Karlin KL; Westbrook TF; Heiser LM; Anur P; Spellman P; Guichard SM; Smith PD; Davies BR; Klinowska T; Lee AV; Mills GB; Rimawi MF; Hilsenbeck SG; Gray JW; Joshi A; Osborne CK; Schiff R Breast Cancer Res; 2014 Sep; 16(5):430. PubMed ID: 25212826 [TBL] [Abstract][Full Text] [Related]
6. AKT Antagonist AZD5363 Influences Estrogen Receptor Function in Endocrine-Resistant Breast Cancer and Synergizes with Fulvestrant (ICI182780) In Vivo. Ribas R; Pancholi S; Guest SK; Marangoni E; Gao Q; Thuleau A; Simigdala N; Polanska UM; Campbell H; Rani A; Liccardi G; Johnston S; Davies BR; Dowsett M; Martin LA Mol Cancer Ther; 2015 Sep; 14(9):2035-48. PubMed ID: 26116361 [TBL] [Abstract][Full Text] [Related]
7. Impact of dual mTORC1/2 mTOR kinase inhibitor AZD8055 on acquired endocrine resistance in breast cancer in vitro. Jordan NJ; Dutkowski CM; Barrow D; Mottram HJ; Hutcheson IR; Nicholson RI; Guichard SM; Gee JM Breast Cancer Res; 2014 Jan; 16(1):R12. PubMed ID: 24457069 [TBL] [Abstract][Full Text] [Related]
8. Inhibitory role of large intergenic noncoding RNA-ROR on tamoxifen resistance in the endocrine therapy of breast cancer by regulating the PI3K/Akt/mTOR signaling pathway. Lu PW; Li L; Wang F; Gu YT J Cell Physiol; 2019 Feb; 234(2):1904-1912. PubMed ID: 30145819 [TBL] [Abstract][Full Text] [Related]
9. PIK3CA mutations, phosphatase and tensin homolog, human epidermal growth factor receptor 2, and insulin-like growth factor 1 receptor and adjuvant tamoxifen resistance in postmenopausal breast cancer patients. Beelen K; Opdam M; Severson TM; Koornstra RH; Vincent AD; Wesseling J; Muris JJ; Berns EM; Vermorken JB; van Diest PJ; Linn SC Breast Cancer Res; 2014 Jan; 16(1):R13. PubMed ID: 24467828 [TBL] [Abstract][Full Text] [Related]
10. Hedgehog signaling is a novel therapeutic target in tamoxifen-resistant breast cancer aberrantly activated by PI3K/AKT pathway. Ramaswamy B; Lu Y; Teng KY; Nuovo G; Li X; Shapiro CL; Majumder S Cancer Res; 2012 Oct; 72(19):5048-59. PubMed ID: 22875023 [TBL] [Abstract][Full Text] [Related]
11. Downregulation of BAG‑1 in T47D cells promotes resistance to tamoxifen via activation of the PI3K/Akt/mTOR signaling pathway. Lu S; Du Y; Cui F; Feng X; Ma Y; Liu H Oncol Rep; 2019 Mar; 41(3):1901-1910. PubMed ID: 30747221 [TBL] [Abstract][Full Text] [Related]
12. Inhibition of mTOR activity restores tamoxifen response in breast cancer cells with aberrant Akt Activity. deGraffenried LA; Friedrichs WE; Russell DH; Donzis EJ; Middleton AK; Silva JM; Roth RA; Hidalgo M Clin Cancer Res; 2004 Dec; 10(23):8059-67. PubMed ID: 15585641 [TBL] [Abstract][Full Text] [Related]
13. Dual inhibition of PI3K and mTOR mitigates compensatory AKT activation and improves tamoxifen response in breast cancer. Chen X; Zhao M; Hao M; Sun X; Wang J; Mao Y; Zu L; Liu J; Shen Y; Wang J; Shen K Mol Cancer Res; 2013 Oct; 11(10):1269-78. PubMed ID: 23814023 [TBL] [Abstract][Full Text] [Related]
14. M2‑like tumour‑associated macrophage‑secreted IGF promotes thyroid cancer stemness and metastasis by activating the PI3K/AKT/mTOR pathway. Lv J; Liu C; Chen FK; Feng ZP; Jia L; Liu PJ; Yang ZX; Hou F; Deng ZY Mol Med Rep; 2021 Aug; 24(2):. PubMed ID: 34184083 [TBL] [Abstract][Full Text] [Related]
15. PI3K/AKT/mTOR pathway activation in primary and corresponding metastatic breast tumors after adjuvant endocrine therapy. Beelen K; Hoefnagel LD; Opdam M; Wesseling J; Sanders J; Vincent AD; van Diest PJ; Linn SC Int J Cancer; 2014 Sep; 135(5):1257-63. PubMed ID: 24501006 [TBL] [Abstract][Full Text] [Related]
16. Endocrine resistance associated with activated ErbB system in breast cancer cells is reversed by inhibiting MAPK or PI3K/Akt signaling pathways. Ghayad SE; Vendrell JA; Ben Larbi S; Dumontet C; Bieche I; Cohen PA Int J Cancer; 2010 Jan; 126(2):545-62. PubMed ID: 19609946 [TBL] [Abstract][Full Text] [Related]
17. Molecular characterization of anastrozole resistance in breast cancer: pivotal role of the Akt/mTOR pathway in the emergence of de novo or acquired resistance and importance of combining the allosteric Akt inhibitor MK-2206 with an aromatase inhibitor. Vilquin P; Villedieu M; Grisard E; Ben Larbi S; Ghayad SE; Heudel PE; Bachelot T; Corbo L; Treilleux I; Vendrell JA; Cohen PA Int J Cancer; 2013 Oct; 133(7):1589-602. PubMed ID: 23553037 [TBL] [Abstract][Full Text] [Related]
18. Activation of PI3K/Akt/mTOR signaling in the tumor stroma drives endocrine therapy-dependent breast tumor regression. Polo ML; Riggio M; May M; Rodríguez MJ; Perrone MC; Stallings-Mann M; Kaen D; Frost M; Goetz M; Boughey J; Lanari C; Radisky D; Novaro V Oncotarget; 2015 Sep; 6(26):22081-97. PubMed ID: 26098779 [TBL] [Abstract][Full Text] [Related]
19. Phosphorylated p-70S6K predicts tamoxifen resistance in postmenopausal breast cancer patients randomized between adjuvant tamoxifen versus no systemic treatment. Beelen K; Opdam M; Severson TM; Koornstra RH; Vincent AD; Wesseling J; Muris JJ; Berns EM; Vermorken JB; van Diest PJ; Linn SC Breast Cancer Res; 2014 Jan; 16(1):R6. PubMed ID: 24447434 [TBL] [Abstract][Full Text] [Related]
20. Mechanism of resistance to endocrine therapy in breast cancer: the important role of PI3K/Akt/mTOR in estrogen receptor-positive, HER2-negative breast cancer. Araki K; Miyoshi Y Breast Cancer; 2018 Jul; 25(4):392-401. PubMed ID: 29086897 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]