180 related articles for article (PubMed ID: 34623375)
1. Targeting small GTPases and their downstream pathways with intracellular macromolecule binders to define alternative therapeutic strategies in cancer.
Sorbara M; Bery N
Biochem Soc Trans; 2021 Nov; 49(5):2021-2035. PubMed ID: 34623375
[TBL] [Abstract][Full Text] [Related]
2. Approaches of targeting Rho GTPases in cancer drug discovery.
Lin Y; Zheng Y
Expert Opin Drug Discov; 2015; 10(9):991-1010. PubMed ID: 26087073
[TBL] [Abstract][Full Text] [Related]
3. Drugging the Small GTPase Pathways in Cancer Treatment: Promises and Challenges.
Prieto-Dominguez N; Parnell C; Teng Y
Cells; 2019 Mar; 8(3):. PubMed ID: 30884855
[TBL] [Abstract][Full Text] [Related]
4. Early-stage structure-based drug discovery for small GTPases by NMR spectroscopy.
Yin G; Lv G; Zhang J; Jiang H; Lai T; Yang Y; Ren Y; Wang J; Yi C; Chen H; Huang Y; Xiao C
Pharmacol Ther; 2022 Aug; 236():108110. PubMed ID: 35007659
[TBL] [Abstract][Full Text] [Related]
5. Targeting the Small GTPase Superfamily through Their Regulatory Proteins.
Gray JL; von Delft F; Brennan PE
Angew Chem Int Ed Engl; 2020 Apr; 59(16):6342-6366. PubMed ID: 30869179
[TBL] [Abstract][Full Text] [Related]
6. Direct Modulation of Small GTPase Activity and Function.
Cromm PM; Spiegel J; Grossmann TN; Waldmann H
Angew Chem Int Ed Engl; 2015 Nov; 54(46):13516-37. PubMed ID: 26470842
[TBL] [Abstract][Full Text] [Related]
7. Cdc42 Signaling Pathway Inhibition as a Therapeutic Target in Ras- Related Cancers.
Aguilar BJ; Zhou H; Lu Q
Curr Med Chem; 2017; 24(32):3485-3507. PubMed ID: 28571533
[TBL] [Abstract][Full Text] [Related]
8. Protein-membrane interactions in small GTPase signalling and pharmacology: perspectives from Arf GTPases studies.
Nawrotek A; Zeghouf M; Cherfils J
Biochem Soc Trans; 2020 Dec; 48(6):2721-2728. PubMed ID: 33336699
[TBL] [Abstract][Full Text] [Related]
9. Targeting and localized signalling by small GTPases.
ten Klooster JP; Hordijk PL
Biol Cell; 2007 Jan; 99(1):1-12. PubMed ID: 17155934
[TBL] [Abstract][Full Text] [Related]
10. Simvastatin inhibits T-cell activation by selectively impairing the function of Ras superfamily GTPases.
Ghittoni R; Patrussi L; Pirozzi K; Pellegrini M; Lazzerini PE; Capecchi PL; Pasini FL; Baldari CT
FASEB J; 2005 Apr; 19(6):605-7. PubMed ID: 15677697
[TBL] [Abstract][Full Text] [Related]
11. Atypical GTPases as drug targets.
Soundararajan M; Eswaran J
Anticancer Agents Med Chem; 2012 Jan; 12(1):19-28. PubMed ID: 21707505
[TBL] [Abstract][Full Text] [Related]
12. The role of prenylated small GTP-binding proteins in the regulation of osteoclast function.
Coxon FP; Rogers MJ
Calcif Tissue Int; 2003 Jan; 72(1):80-4. PubMed ID: 12370802
[TBL] [Abstract][Full Text] [Related]
13. Molecular pathways: targeting the kinase effectors of RHO-family GTPases.
Prudnikova TY; Rawat SJ; Chernoff J
Clin Cancer Res; 2015 Jan; 21(1):24-9. PubMed ID: 25336694
[TBL] [Abstract][Full Text] [Related]
14. The interplay between IQGAP1 and small GTPases in cancer metastasis.
Peng X; Wang T; Gao H; Yue X; Bian W; Mei J; Zhang Y
Biomed Pharmacother; 2021 Mar; 135():111243. PubMed ID: 33434854
[TBL] [Abstract][Full Text] [Related]
15. Targeting Small GTPases and Their Prenylation in Diabetes Mellitus.
Gendaszewska-Darmach E; Garstka MA; Błażewska KM
J Med Chem; 2021 Jul; 64(14):9677-9710. PubMed ID: 34236862
[TBL] [Abstract][Full Text] [Related]
16. Blocking Ras inhibition as an antitumor strategy.
Marín-Ramos NI; Ortega-Gutiérrez S; López-Rodríguez ML
Semin Cancer Biol; 2019 Feb; 54():91-100. PubMed ID: 29409706
[TBL] [Abstract][Full Text] [Related]
17. Conformational resolution of nucleotide cycling and effector interactions for multiple small GTPases determined in parallel.
Killoran RC; Smith MJ
J Biol Chem; 2019 Jun; 294(25):9937-9948. PubMed ID: 31088913
[TBL] [Abstract][Full Text] [Related]
18. Protein binders and their applications in developmental biology.
Harmansa S; Affolter M
Development; 2018 Jan; 145(2):. PubMed ID: 29374062
[TBL] [Abstract][Full Text] [Related]
19. Bioblockades join the assault on small G protein signalling.
Mott HR; Owen D
Semin Cancer Biol; 2019 Feb; 54():149-161. PubMed ID: 29307570
[TBL] [Abstract][Full Text] [Related]
20. [Rho GTPases as molecular targets in cancer. Strategies and therapeutic opportunities].
Maggio J; González N; Cardama GA; Gomez DE
Medicina (B Aires); 2017; 77(6):497-504. PubMed ID: 29223942
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
