179 related articles for article (PubMed ID: 34624079)
1. SHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma.
Wilke AC; Doebele C; Zindel A; Lee KS; Rieke SA; Ceribelli M; Comoglio F; Phelan JD; Wang JQ; Pikman Y; Jahn D; Häupl B; Schneider C; Scheich S; Tosto FA; Bohnenberger H; Stauder P; Schnütgen F; Slabicki M; Coulibaly ZA; Wolf S; Bojarczuk K; Chapuy B; Brandts CH; Stroebel P; Lewis CA; Engelke M; Xu X; Kim H; Dang TH; Schmitz R; Hodson DJ; Stegmaier K; Urlaub H; Serve H; Schmitt CA; Kreuz F; Knittel G; Rabinowitz JD; Reinhardt HC; Vander Heiden MG; Thomas C; Staudt LM; Zenz T; Oellerich T
Blood; 2022 Jan; 139(4):538-553. PubMed ID: 34624079
[TBL] [Abstract][Full Text] [Related]
2. Burkitt lymphoma-related
Yamazaki T; Liu L; Conlon EG; Manley JL
RNA Biol; 2020 Oct; 17(10):1383-1390. PubMed ID: 32449435
[TBL] [Abstract][Full Text] [Related]
3. Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics.
Schmitz R; Young RM; Ceribelli M; Jhavar S; Xiao W; Zhang M; Wright G; Shaffer AL; Hodson DJ; Buras E; Liu X; Powell J; Yang Y; Xu W; Zhao H; Kohlhammer H; Rosenwald A; Kluin P; Müller-Hermelink HK; Ott G; Gascoyne RD; Connors JM; Rimsza LM; Campo E; Jaffe ES; Delabie J; Smeland EB; Ogwang MD; Reynolds SJ; Fisher RI; Braziel RM; Tubbs RR; Cook JR; Weisenburger DD; Chan WC; Pittaluga S; Wilson W; Waldmann TA; Rowe M; Mbulaiteye SM; Rickinson AB; Staudt LM
Nature; 2012 Oct; 490(7418):116-20. PubMed ID: 22885699
[TBL] [Abstract][Full Text] [Related]
4. SHMT2 promotes cell viability and inhibits ROS-dependent, mitochondrial-mediated apoptosis via the intrinsic signaling pathway in bladder cancer cells.
Zhang Y; Liu Z; Wang X; Jian H; Xiao H; Wen T
Cancer Gene Ther; 2022 Oct; 29(10):1514-1527. PubMed ID: 35422087
[TBL] [Abstract][Full Text] [Related]
5. Transcription factor 3 (TCF3) combined with histone deacetylase 3 (HDAC3) down-regulates microRNA-101 to promote Burkitt lymphoma cell proliferation and inhibit apoptosis.
Dong L; Huang J; Zu P; Liu J; Gao X; Du J; Li Y
Bioengineered; 2021 Dec; 12(1):7995-8005. PubMed ID: 34658308
[TBL] [Abstract][Full Text] [Related]
6. Downregulating serine hydroxymethyltransferase 2 (SHMT2) suppresses tumorigenesis in human hepatocellular carcinoma.
Woo CC; Chen WC; Teo XQ; Radda GK; Lee PT
Oncotarget; 2016 Aug; 7(33):53005-53017. PubMed ID: 27391339
[TBL] [Abstract][Full Text] [Related]
7. Cancer proteome and metabolite changes linked to SHMT2.
Tong J; Krieger JR; Taylor P; Bagshaw R; Kang J; Jeedigunta S; Wybenga-Groot LE; Zhang W; Badr H; Mirhadi S; Pham NA; Coyaud É; Yu M; Li M; Cabanero M; Raught B; Maynes JT; Hawkins C; Tsao MS; Moran MF
PLoS One; 2020; 15(9):e0237981. PubMed ID: 32903271
[TBL] [Abstract][Full Text] [Related]
8. Cytoplasmic SHMT2 drives the progression and metastasis of colorectal cancer by inhibiting β-catenin degradation.
Liu C; Wang L; Liu X; Tan Y; Tao L; Xiao Y; Deng P; Wang H; Deng Q; Lin Y; Jie H; Zhang H; Zhang J; Peng Y; Zhang H; Zhou Z; Sun Q; Cen X; Zhao Y
Theranostics; 2021; 11(6):2966-2986. PubMed ID: 33456583
[No Abstract] [Full Text] [Related]
9. The role of SHMT2 in modulating lipid metabolism in hepatocytes via glycine-mediated mTOR activation.
Choi YJ; Lee G; Yun SH; Lee W; Yu J; Kim SK; Lee BH
Amino Acids; 2022 May; 54(5):823-834. PubMed ID: 35212811
[TBL] [Abstract][Full Text] [Related]
10. Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma.
Ducker GS; Ghergurovich JM; Mainolfi N; Suri V; Jeong SK; Hsin-Jung Li S; Friedman A; Manfredi MG; Gitai Z; Kim H; Rabinowitz JD
Proc Natl Acad Sci U S A; 2017 Oct; 114(43):11404-11409. PubMed ID: 29073064
[TBL] [Abstract][Full Text] [Related]
11. Human Cytosolic and Mitochondrial Serine Hydroxymethyltransferase Isoforms in Comparison: Full Kinetic Characterization and Substrate Inhibition Properties.
Tramonti A; Nardella C; di Salvo ML; Barile A; Cutruzzolà F; Contestabile R
Biochemistry; 2018 Dec; 57(51):6984-6996. PubMed ID: 30500180
[TBL] [Abstract][Full Text] [Related]
12. Structural basis of inhibition of the human serine hydroxymethyltransferase SHMT2 by antifolate drugs.
Scaletti E; Jemth AS; Helleday T; Stenmark P
FEBS Lett; 2019 Jul; 593(14):1863-1873. PubMed ID: 31127856
[TBL] [Abstract][Full Text] [Related]
13. Identification of three new compounds that directly target human serine hydroxymethyltransferase 2.
Han Y; He L; Qi Y; Zhao Y; Pan Y; Fang B; Li S; Zhang JZH; Zhang L
Chem Biol Drug Des; 2021 Feb; 97(2):221-230. PubMed ID: 32779873
[TBL] [Abstract][Full Text] [Related]
14. Inhibition of Hsp90 Suppresses PI3K/AKT/mTOR Signaling and Has Antitumor Activity in Burkitt Lymphoma.
Giulino-Roth L; van Besien HJ; Dalton T; Totonchy JE; Rodina A; Taldone T; Bolaender A; Erdjument-Bromage H; Sadek J; Chadburn A; Barth MJ; Dela Cruz FS; Rainey A; Kung AL; Chiosis G; Cesarman E
Mol Cancer Ther; 2017 Sep; 16(9):1779-1790. PubMed ID: 28619753
[TBL] [Abstract][Full Text] [Related]
15. HSP90 promotes Burkitt lymphoma cell survival by maintaining tonic B-cell receptor signaling.
Walter R; Pan KT; Doebele C; Comoglio F; Tomska K; Bohnenberger H; Young RM; Jacobs L; Keller U; Bönig H; Engelke M; Rosenwald A; Urlaub H; Staudt LM; Serve H; Zenz T; Oellerich T
Blood; 2017 Feb; 129(5):598-608. PubMed ID: 28064214
[TBL] [Abstract][Full Text] [Related]
16. Serine Catabolism by SHMT2 Is Required for Proper Mitochondrial Translation Initiation and Maintenance of Formylmethionyl-tRNAs.
Minton DR; Nam M; McLaughlin DJ; Shin J; Bayraktar EC; Alvarez SW; Sviderskiy VO; Papagiannakopoulos T; Sabatini DM; Birsoy K; Possemato R
Mol Cell; 2018 Feb; 69(4):610-621.e5. PubMed ID: 29452640
[TBL] [Abstract][Full Text] [Related]
17. Induction of serine hydroxymethyltransferase 2 promotes tumorigenesis and metastasis in neuroblastoma.
Clark RA; Qiao J; Jacobson JC; Chung DH
Oncotarget; 2022; 13():32-45. PubMed ID: 35018218
[TBL] [Abstract][Full Text] [Related]
18. SHMT2 Desuccinylation by SIRT5 Drives Cancer Cell Proliferation.
Yang X; Wang Z; Li X; Liu B; Liu M; Liu L; Chen S; Ren M; Wang Y; Yu M; Wang B; Zou J; Zhu WG; Yin Y; Gu W; Luo J
Cancer Res; 2018 Jan; 78(2):372-386. PubMed ID: 29180469
[TBL] [Abstract][Full Text] [Related]
19. Study of SHMT2 Inhibitors and Their Binding Mechanism by Computational Alanine Scanning.
He L; Bao J; Yang Y; Dong S; Zhang L; Qi Y; Zhang JZH
J Chem Inf Model; 2019 Sep; 59(9):3871-3878. PubMed ID: 31442042
[TBL] [Abstract][Full Text] [Related]
20. Serine catabolism regulates mitochondrial redox control during hypoxia.
Ye J; Fan J; Venneti S; Wan YW; Pawel BR; Zhang J; Finley LW; Lu C; Lindsten T; Cross JR; Qing G; Liu Z; Simon MC; Rabinowitz JD; Thompson CB
Cancer Discov; 2014 Dec; 4(12):1406-17. PubMed ID: 25186948
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
