BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

126 related articles for article (PubMed ID: 34624316)

  • 1. Identification of Rac guanine nucleotide exchange factors promoting Lgl1 phosphorylation in glioblastoma.
    Lavictoire SJ; Jomaa D; Gont A; Jardine K; Cook DP; Lorimer IAJ
    J Biol Chem; 2021 Nov; 297(5):101172. PubMed ID: 34624316
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PREX1 integrates G protein-coupled receptor and phosphoinositide 3-kinase signaling to promote glioblastoma invasion.
    Gont A; Daneshmand M; Woulfe J; Lavictoire SJ; Lorimer IA
    Oncotarget; 2017 Jan; 8(5):8559-8573. PubMed ID: 28051998
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PREX1 Protein Function Is Negatively Regulated Downstream of Receptor Tyrosine Kinase Activation by p21-activated Kinases (PAKs).
    Barrows D; He JZ; Parsons R
    J Biol Chem; 2016 Sep; 291(38):20042-54. PubMed ID: 27481946
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PtdIns(3,4,5)P3-dependent Rac Exchanger 1 (PREX1) Rac-Guanine Nucleotide Exchange Factor (GEF) Activity Promotes Breast Cancer Cell Proliferation and Tumor Growth via Activation of Extracellular Signal-regulated Kinase 1/2 (ERK1/2) Signaling.
    Liu HJ; Ooms LM; Srijakotre N; Man J; Vieusseux J; Waters JE; Feng Y; Bailey CG; Rasko JE; Price JT; Mitchell CA
    J Biol Chem; 2016 Aug; 291(33):17258-70. PubMed ID: 27358402
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulation of breast cancer cell motility by T-cell lymphoma invasion and metastasis-inducing protein.
    Adams HC; Chen R; Liu Z; Whitehead IP
    Breast Cancer Res; 2010; 12(5):R69. PubMed ID: 20819206
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Regulation of p70 S6 kinase by complex formation between the Rac guanine nucleotide exchange factor (Rac-GEF) Tiam1 and the scaffold spinophilin.
    Buchsbaum RJ; Connolly BA; Feig LA
    J Biol Chem; 2003 May; 278(21):18833-41. PubMed ID: 12531897
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Rac activation by lysophosphatidic acid LPA1 receptors through the guanine nucleotide exchange factor Tiam1.
    Van Leeuwen FN; Olivo C; Grivell S; Giepmans BN; Collard JG; Moolenaar WH
    J Biol Chem; 2003 Jan; 278(1):400-6. PubMed ID: 12393875
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hepatocyte growth factor triggers distinct mechanisms of Asef and Tiam1 activation to induce endothelial barrier enhancement.
    Higginbotham K; Tian Y; Gawlak G; Moldobaeva N; Shah A; Birukova AA
    Cell Signal; 2014 Nov; 26(11):2306-16. PubMed ID: 25101856
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The rac activator Tiam1 is a Wnt-responsive gene that modifies intestinal tumor development.
    Malliri A; Rygiel TP; van der Kammen RA; Song JY; Engers R; Hurlstone AF; Clevers H; Collard JG
    J Biol Chem; 2006 Jan; 281(1):543-8. PubMed ID: 16249175
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Aberrant Rac pathway signalling in glioblastoma.
    Lorimer IA
    Small GTPases; 2021 Mar; 12(2):81-95. PubMed ID: 31032735
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The sirtuins promote Dishevelled-1 scaffolding of TIAM1, Rac activation and cell migration.
    Saxena M; Dykes SS; Malyarchuk S; Wang AE; Cardelli JA; Pruitt K
    Oncogene; 2015 Jan; 34(2):188-98. PubMed ID: 24362520
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Subtype-specific overexpression of the Rac-GEF P-REX1 in breast cancer is associated with promoter hypomethylation.
    Barrio-Real L; Benedetti LG; Engel N; Tu Y; Cho S; Sukumar S; Kazanietz MG
    Breast Cancer Res; 2014 Sep; 16(5):441. PubMed ID: 25248717
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The Rac-GAP Bcr is a novel regulator of the Par complex that controls cell polarity.
    Narayanan AS; Reyes SB; Um K; McCarty JH; Tolias KF
    Mol Biol Cell; 2013 Dec; 24(24):3857-68. PubMed ID: 24152735
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of glioblastoma malignancy by Lgl1.
    Gont A; Hanson JE; Lavictoire SJ; Daneshmand M; Nicholas G; Woulfe J; Kassam A; Da Silva VF; Lorimer IA
    Oncotarget; 2014 Nov; 5(22):11541-51. PubMed ID: 25426552
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Translocation of the Rac1 guanine nucleotide exchange factor Tiam1 induced by platelet-derived growth factor and lysophosphatidic acid.
    Buchanan FG; Elliot CM; Gibbs M; Exton JH
    J Biol Chem; 2000 Mar; 275(13):9742-8. PubMed ID: 10734127
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The guanine nucleotide exchange factor Tiam1: a Janus-faced molecule in cellular signaling.
    Boissier P; Huynh-Do U
    Cell Signal; 2014 Mar; 26(3):483-91. PubMed ID: 24308970
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tiam1 interaction with the PAR complex promotes talin-mediated Rac1 activation during polarized cell migration.
    Wang S; Watanabe T; Matsuzawa K; Katsumi A; Kakeno M; Matsui T; Ye F; Sato K; Murase K; Sugiyama I; Kimura K; Mizoguchi A; Ginsberg MH; Collard JG; Kaibuchi K
    J Cell Biol; 2012 Oct; 199(2):331-45. PubMed ID: 23071154
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The role of the guanine nucleotide exchange factor Tiam1 in cellular migration, invasion, adhesion and tumor progression.
    Minard ME; Kim LS; Price JE; Gallick GE
    Breast Cancer Res Treat; 2004 Mar; 84(1):21-32. PubMed ID: 14999151
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The guanine nucleotide exchange factor Tiam1 affects neuronal morphology; opposing roles for the small GTPases Rac and Rho.
    Leeuwen FN; Kain HE; Kammen RA; Michiels F; Kranenburg OW; Collard JG
    J Cell Biol; 1997 Nov; 139(3):797-807. PubMed ID: 9348295
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Rac-1 superactivation triggers insulin-independent glucose transporter 4 (GLUT4) translocation that bypasses signaling defects exerted by c-Jun N-terminal kinase (JNK)- and ceramide-induced insulin resistance.
    Chiu TT; Sun Y; Koshkina A; Klip A
    J Biol Chem; 2013 Jun; 288(24):17520-31. PubMed ID: 23640896
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.