142 related articles for article (PubMed ID: 34624330)
1. Inhibition of the NLRP3 inflammasome by OLT1177 induces functional protection and myelin preservation after spinal cord injury.
Amo-Aparicio J; Garcia-Garcia J; Puigdomenech M; Francos-Quijorna I; Skouras DB; Dinarello CA; Lopez-Vales R
Exp Neurol; 2022 Jan; 347():113889. PubMed ID: 34624330
[TBL] [Abstract][Full Text] [Related]
2. OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation.
Marchetti C; Swartzwelter B; Gamboni F; Neff CP; Richter K; Azam T; Carta S; Tengesdal I; Nemkov T; D'Alessandro A; Henry C; Jones GS; Goodrich SA; St Laurent JP; Jones TM; Scribner CL; Barrow RB; Altman RD; Skouras DB; Gattorno M; Grau V; Janciauskiene S; Rubartelli A; Joosten LAB; Dinarello CA
Proc Natl Acad Sci U S A; 2018 Feb; 115(7):E1530-E1539. PubMed ID: 29378952
[TBL] [Abstract][Full Text] [Related]
3. NLRP3 inflammasome inhibitor OLT1177 suppresses joint inflammation in murine models of acute arthritis.
Marchetti C; Swartzwelter B; Koenders MI; Azam T; Tengesdal IW; Powers N; de Graaf DM; Dinarello CA; Joosten LAB
Arthritis Res Ther; 2018 Aug; 20(1):169. PubMed ID: 30075804
[TBL] [Abstract][Full Text] [Related]
4. OLT1177 (Dapansutrile), a Selective NLRP3 Inflammasome Inhibitor, Ameliorates Experimental Autoimmune Encephalomyelitis Pathogenesis.
Sánchez-Fernández A; Skouras DB; Dinarello CA; López-Vales R
Front Immunol; 2019; 10():2578. PubMed ID: 31736980
[TBL] [Abstract][Full Text] [Related]
5. Inhibition of NLRP3 inflammasome attenuates spinal cord injury-induced lung injury in mice.
Jiang W; Li M; He F; Zhu L
J Cell Physiol; 2019 May; 234(5):6012-6022. PubMed ID: 30589073
[TBL] [Abstract][Full Text] [Related]
6. The effect of the "segment" of spinal cord injury on the activity of the nucleotide-binding domain-like receptor protein 3 inflammasome and response to hormonal therapy.
Majidpoor J; Mortezaee K; Khezri Z; Fathi F; Zali A; Derakhshan HB; Bariki MG; Joghataie MT; Shirazi R; Moradi F
Cell Biochem Funct; 2021 Mar; 39(2):267-276. PubMed ID: 32893892
[TBL] [Abstract][Full Text] [Related]
7. The NLRP3 inhibitor, OLT1177 attenuates brain injury in experimental intracerebral hemorrhage.
Fang M; Xia F; Wang J; Wang C; Teng B; You S; Li M; Chen X; Hu X
Int Immunopharmacol; 2024 Apr; 131():111869. PubMed ID: 38492343
[TBL] [Abstract][Full Text] [Related]
8. Targeting the NLRP3 inflammasome to attenuate spinal cord injury in mice.
Jiang W; Li M; He F; Zhou S; Zhu L
J Neuroinflammation; 2017 Oct; 14(1):207. PubMed ID: 29070054
[TBL] [Abstract][Full Text] [Related]
9. The NLRP3 inflammasome inhibitor OLT1177 rescues cognitive impairment in a mouse model of Alzheimer's disease.
Lonnemann N; Hosseini S; Marchetti C; Skouras DB; Stefanoni D; D'Alessandro A; Dinarello CA; Korte M
Proc Natl Acad Sci U S A; 2020 Dec; 117(50):32145-32154. PubMed ID: 33257576
[TBL] [Abstract][Full Text] [Related]
10. Dopamine D1 Receptor Agonist A-68930 Inhibits NLRP3 Inflammasome Activation, Controls Inflammation, and Alleviates Histopathology in a Rat Model of Spinal Cord Injury.
Jiang W; Huang Y; He F; Liu J; Li M; Sun T; Ren W; Hou J; Zhu L
Spine (Phila Pa 1976); 2016 Mar; 41(6):E330-4. PubMed ID: 26966979
[TBL] [Abstract][Full Text] [Related]
11. BBG enhances OLT1177-induced NLRP3 inflammasome inactivation by targeting P2X7R/NLRP3 and MyD88/NF-κB signaling in DSS-induced colitis in rats.
Saber S; Youssef ME; Sharaf H; Amin NA; El-Shedody R; Aboutouk FH; El-Galeel YA; El-Hefnawy A; Shabaka D; Khalifa A; Saleh RA; Osama D; El-Zoghby G; Gobba NA
Life Sci; 2021 Apr; 270():119123. PubMed ID: 33548287
[TBL] [Abstract][Full Text] [Related]
12. Activation and Regulation of NLRP3 Inflammasome by Intrathecal Application of SDF-1a in a Spinal Cord Injury Model.
Zendedel A; Johann S; Mehrabi S; Joghataei MT; Hassanzadeh G; Kipp M; Beyer C
Mol Neurobiol; 2016 Jul; 53(5):3063-3075. PubMed ID: 25972240
[TBL] [Abstract][Full Text] [Related]
13. The NLRP3 Inflammasome Inhibitor, OLT1177 (Dapansutrile), Reduces Infarct Size and Preserves Contractile Function After Ischemia Reperfusion Injury in the Mouse.
Toldo S; Mauro AG; Cutter Z; Van Tassell BW; Mezzaroma E; Del Buono MG; Prestamburgo A; Potere N; Abbate A
J Cardiovasc Pharmacol; 2019 Apr; 73(4):215-222. PubMed ID: 30747785
[TBL] [Abstract][Full Text] [Related]
14. Preservation of Contractile Reserve and Diastolic Function by Inhibiting the NLRP3 Inflammasome with OLT1177
Aliaga J; Bonaventura A; Mezzaroma E; Dhakal Y; Mauro AG; Abbate A; Toldo S
Molecules; 2021 Jun; 26(12):. PubMed ID: 34207886
[TBL] [Abstract][Full Text] [Related]
15. Oral treatment with glycyrrhizin inhibits NLRP3 inflammasome activation and promotes microglial M2 polarization after traumatic spinal cord injury.
Su XQ; Wang XY; Gong FT; Feng M; Bai JJ; Zhang RR; Dang XQ
Brain Res Bull; 2020 May; 158():1-8. PubMed ID: 32092434
[TBL] [Abstract][Full Text] [Related]
16. Impairment of autophagy after spinal cord injury potentiates neuroinflammation and motor function deficit in mice.
Li Y; Lei Z; Ritzel RM; He J; Li H; Choi HMC; Lipinski MM; Wu J
Theranostics; 2022; 12(12):5364-5388. PubMed ID: 35910787
[TBL] [Abstract][Full Text] [Related]
17. Neuroprotective effects of tetramethylpyrazine on spinal cord injury-Related neuroinflammation mediated by P2X7R/NLRP3 interaction.
Fan X; Zang C; Lao K; Mu XH; Dai S
Eur J Pharmacol; 2024 Feb; 964():176267. PubMed ID: 38072038
[TBL] [Abstract][Full Text] [Related]
18. PPAR-
Meng QQ; Feng ZC; Zhang XL; Hu LQ; Wang M; Zhang HF; Li SM
Mediators Inflamm; 2019; 2019():6386729. PubMed ID: 31015796
[TBL] [Abstract][Full Text] [Related]
19. Estrogen Attenuates Local Inflammasome Expression and Activation after Spinal Cord Injury.
Zendedel A; Mönnink F; Hassanzadeh G; Zaminy A; Ansar MM; Habib P; Slowik A; Kipp M; Beyer C
Mol Neurobiol; 2018 Feb; 55(2):1364-1375. PubMed ID: 28127698
[TBL] [Abstract][Full Text] [Related]
20. Ultrashort Wave Combined with Human Umbilical Cord Mesenchymal Stem Cell (HUC-MSC) Transplantation Inhibits NLRP3 Inflammasome and Improves Spinal Cord Injury via MK2/TTP Signalling Pathway.
Na L; Wang S; Liu T; Zhang L
Biomed Res Int; 2020; 2020():3021750. PubMed ID: 33376718
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]