143 related articles for article (PubMed ID: 34637790)
1. Tryptophan (W) at position 37 of murine IL-12/IL-23 p40 is mandatory for binding to IL-12Rβ1 and subsequent signal transduction.
Georgy J; Arlt Y; Moll JM; Ouzin M; Weitz HT; Gremer L; Willbold D; Grötzinger J; Thives-Kurenbach F; Scheller J; Floss DM
J Biol Chem; 2021 Nov; 297(5):101295. PubMed ID: 34637790
[TBL] [Abstract][Full Text] [Related]
2. Deciphering site 3 interactions of interleukin 12 and interleukin 23 with their cognate murine and human receptors.
Esch A; Masiarz A; Mossner S; Moll JM; Grötzinger J; Schröder J; Scheller J; Floss DM
J Biol Chem; 2020 Jul; 295(30):10478-10492. PubMed ID: 32518162
[TBL] [Abstract][Full Text] [Related]
3. Non-canonical interleukin 23 receptor complex assembly: p40 protein recruits interleukin 12 receptor β1 via site II and induces p19/interleukin 23 receptor interaction via site III.
Schröder J; Moll JM; Baran P; Grötzinger J; Scheller J; Floss DM
J Biol Chem; 2015 Jan; 290(1):359-70. PubMed ID: 25371211
[TBL] [Abstract][Full Text] [Related]
4. IL-12 p40 monomer is different from other IL-12 family members to selectively inhibit IL-12Rβ1 internalization and suppress EAE.
Mondal S; Kundu M; Jana M; Roy A; Rangasamy SB; Modi KK; Wallace J; Albalawi YA; Balabanov R; Pahan K
Proc Natl Acad Sci U S A; 2020 Sep; 117(35):21557-21567. PubMed ID: 32817415
[TBL] [Abstract][Full Text] [Related]
5. Structural basis for IL-12 and IL-23 receptor sharing reveals a gateway for shaping actions on T versus NK cells.
Glassman CR; Mathiharan YK; Jude KM; Su L; Panova O; Lupardus PJ; Spangler JB; Ely LK; Thomas C; Skiniotis G; Garcia KC
Cell; 2021 Feb; 184(4):983-999.e24. PubMed ID: 33606986
[TBL] [Abstract][Full Text] [Related]
6. A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R.
Parham C; Chirica M; Timans J; Vaisberg E; Travis M; Cheung J; Pflanz S; Zhang R; Singh KP; Vega F; To W; Wagner J; O'Farrell AM; McClanahan T; Zurawski S; Hannum C; Gorman D; Rennick DM; Kastelein RA; de Waal Malefyt R; Moore KW
J Immunol; 2002 Jun; 168(11):5699-708. PubMed ID: 12023369
[TBL] [Abstract][Full Text] [Related]
7. Analysis of the multiple interactions between IL-12 and the high affinity IL-12 receptor complex.
Presky DH; Minetti LJ; Gillessen S; Wilkinson VL; Wu CY; Gubler U; Chizzonite R; Gately MK
J Immunol; 1998 Mar; 160(5):2174-9. PubMed ID: 9498755
[TBL] [Abstract][Full Text] [Related]
8. The structure of interleukin-23 reveals the molecular basis of p40 subunit sharing with interleukin-12.
Lupardus PJ; Garcia KC
J Mol Biol; 2008 Oct; 382(4):931-41. PubMed ID: 18680750
[TBL] [Abstract][Full Text] [Related]
9. Defining the functional binding sites of interleukin 12 receptor β1 and interleukin 23 receptor to Janus kinases.
Floss DM; Klöcker T; Schröder J; Lamertz L; Mrotzek S; Strobl B; Hermanns H; Scheller J
Mol Biol Cell; 2016 Jul; 27(14):2301-16. PubMed ID: 27193299
[TBL] [Abstract][Full Text] [Related]
10. Interleukin-12 (IL-12), but not IL-23, induces the expression of IL-7 in microglia and macrophages: implications for multiple sclerosis.
Jana M; Mondal S; Jana A; Pahan K
Immunology; 2014 Apr; 141(4):549-63. PubMed ID: 24224652
[TBL] [Abstract][Full Text] [Related]
11. Synthetic Deletion of the Interleukin 23 Receptor (IL-23R) Stalk Region Led to Autonomous IL-23R Homodimerization and Activation.
Hummel TM; Ackfeld T; Schönberg M; Ciupka G; Schulz F; Oberdoerster A; Grötzinger J; Scheller J; Floss DM
Mol Cell Biol; 2017 Sep; 37(17):. PubMed ID: 28630278
[TBL] [Abstract][Full Text] [Related]
12. Recombinant p35 from bacteria can form Interleukin (IL-)12, but Not IL-35.
Aparicio-Siegmund S; Moll JM; Lokau J; Grusdat M; Schröder J; Plöhn S; Rose-John S; Grötzinger J; Lang PA; Scheller J; Garbers C
PLoS One; 2014; 9(9):e107990. PubMed ID: 25259790
[TBL] [Abstract][Full Text] [Related]
13. Identification of canonical tyrosine-dependent and non-canonical tyrosine-independent STAT3 activation sites in the intracellular domain of the interleukin 23 receptor.
Floss DM; Mrotzek S; Klöcker T; Schröder J; Grötzinger J; Rose-John S; Scheller J
J Biol Chem; 2013 Jul; 288(27):19386-400. PubMed ID: 23673666
[TBL] [Abstract][Full Text] [Related]
14. Characterization of mouse interleukin-12 p40 homodimer binding to the interleukin-12 receptor subunits.
Wang X; Wilkinson VL; Podlaski FJ; Wu C; Stern AS; Presky DH; Magram J
Eur J Immunol; 1999 Jun; 29(6):2007-13. PubMed ID: 10382764
[TBL] [Abstract][Full Text] [Related]
15. IL-12 p40 homodimer, but not IL-12 p70, induces the expression of IL-16 in microglia and macrophages.
Jana M; Pahan K
Mol Immunol; 2009 Feb; 46(5):773-83. PubMed ID: 19100623
[TBL] [Abstract][Full Text] [Related]
16. Functional analyses of the interaction of chicken interleukin 23 subunit p19 with IL-12 subunit p40 to form the IL-23 complex.
Truong AD; Hoang CT; Hong Y; Lee J; Lee K; Lillehoj HS; Hong YH
Mol Immunol; 2017 Dec; 92():54-67. PubMed ID: 29040919
[TBL] [Abstract][Full Text] [Related]
17. A novel class of anti-IL-12p40 antibodies: potent neutralization via inhibition of IL-12-IL-12Rβ2 and IL-23-IL-23R.
Clarke AW; Poulton L; Wai HY; Walker SA; Victor SD; Domagala T; Mraovic D; Butt D; Shewmaker N; Jennings P; Doyle AG
MAbs; 2010; 2(5):539-49. PubMed ID: 20724822
[TBL] [Abstract][Full Text] [Related]
18. Interleukin-23 receptor signaling by interleukin-39 potentiates T cell pathogenicity in acute graft-versus-host disease.
Bastian D; Sui X; Nguyen HD; Wu Y; Schutt S; Tian L; Sofi MH; Liu Y; Martin P; Bartee E; Yu XZ
Am J Transplant; 2021 Nov; 21(11):3538-3549. PubMed ID: 33934505
[TBL] [Abstract][Full Text] [Related]
19. Structural Activation of Pro-inflammatory Human Cytokine IL-23 by Cognate IL-23 Receptor Enables Recruitment of the Shared Receptor IL-12Rβ1.
Bloch Y; Bouchareychas L; Merceron R; Składanowska K; Van den Bossche L; Detry S; Govindarajan S; Elewaut D; Haerynck F; Dullaers M; Adamopoulos IE; Savvides SN
Immunity; 2018 Jan; 48(1):45-58.e6. PubMed ID: 29287995
[TBL] [Abstract][Full Text] [Related]
20. Expression and Function of IL12/23 Related Cytokine Subunits (p35, p40, and p19) in Giant-Cell Arteritis Lesions: Contribution of p40 to Th1- and Th17-Mediated Inflammatory Pathways.
Espígol-Frigolé G; Planas-Rigol E; Lozano E; Corbera-Bellalta M; Terrades-García N; Prieto-González S; García-Martínez A; Hernández-Rodríguez J; Grau JM; Cid MC
Front Immunol; 2018; 9():809. PubMed ID: 29731755
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
