These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

337 related articles for article (PubMed ID: 34638820)

  • 21. DNA Adducts Formed by Aristolochic Acid Are Unique Biomarkers of Exposure and Explain the Initiation Phase of Upper Urothelial Cancer.
    Stiborová M; Arlt VM; Schmeiser HH
    Int J Mol Sci; 2017 Oct; 18(10):. PubMed ID: 29036902
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Enzymes metabolizing aristolochic acid and their contribution to the development of aristolochic acid nephropathy and urothelial cancer.
    Stiborová M; Martínek V; Frei E; Arlt VM; Schmeiser HH
    Curr Drug Metab; 2013 Jul; 14(6):695-705. PubMed ID: 23701164
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Human cytosolic enzymes involved in the metabolic activation of carcinogenic aristolochic acid: evidence for reductive activation by human NAD(P)H:quinone oxidoreductase.
    Stiborová M; Frei E; Sopko B; Sopková K; Marková V; Lanková M; Kumstýrová T; Wiessler M; Schmeiser HH
    Carcinogenesis; 2003 Oct; 24(10):1695-703. PubMed ID: 12869422
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Role of cytochromes P450 1A1/2 in detoxication and activation of carcinogenic aristolochic acid I: studies with the hepatic NADPH:cytochrome P450 reductase null (HRN) mouse model.
    Levová K; Moserová M; Kotrbová V; Sulc M; Henderson CJ; Wolf CR; Phillips DH; Frei E; Schmeiser HH; Mares J; Arlt VM; Stiborová M
    Toxicol Sci; 2011 May; 121(1):43-56. PubMed ID: 21362632
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Sequence-specific detection of aristolochic acid-DNA adducts in the human p53 gene by terminal transferase-dependent PCR.
    Arlt VM; Schmeiser HH; Pfeifer GP
    Carcinogenesis; 2001 Jan; 22(1):133-40. PubMed ID: 11159751
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Evidence for reductive activation of carcinogenic aristolochic acids by prostaglandin H synthase -- (32)P-postlabeling analysis of DNA adduct formation.
    Stiborová M; Frei E; Breuer A; Wiessler M; Schmeiser HH
    Mutat Res; 2001 Jun; 493(1-2):149-60. PubMed ID: 11516724
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Exceptionally long-term persistence of DNA adducts formed by carcinogenic aristolochic acid I in renal tissue from patients with aristolochic acid nephropathy.
    Schmeiser HH; Nortier JL; Singh R; Gamboa da Costa G; Sennesael J; Cassuto-Viguier E; Ambrosetti D; Rorive S; Pozdzik A; Phillips DH; Stiborova M; Arlt VM
    Int J Cancer; 2014 Jul; 135(2):502-7. PubMed ID: 24921086
    [TBL] [Abstract][Full Text] [Related]  

  • 28. The human carcinogen aristolochic acid i is activated to form DNA adducts by human NAD(P)H:quinone oxidoreductase without the contribution of acetyltransferases or sulfotransferases.
    Stiborová M; Mareš J; Frei E; Arlt VM; Martínek V; Schmeiser HH
    Environ Mol Mutagen; 2011 Jul; 52(6):448-59. PubMed ID: 21370283
    [TBL] [Abstract][Full Text] [Related]  

  • 29. NAD(P)H:quinone oxidoreductase expression in Cyp1a-knockout and CYP1A-humanized mouse lines and its effect on bioactivation of the carcinogen aristolochic acid I.
    Levova K; Moserova M; Nebert DW; Phillips DH; Frei E; Schmeiser HH; Arlt VM; Stiborova M
    Toxicol Appl Pharmacol; 2012 Dec; 265(3):360-7. PubMed ID: 22982977
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Differential cytotoxic effects of denitroaristolochic acid II and aristolochic acids on renal epithelial cells.
    Liu Q; Wang Q; Yang X; Shen X; Zhang B
    Toxicol Lett; 2009 Jan; 184(1):5-12. PubMed ID: 19026731
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Chemical and molecular basis of the carcinogenicity of Aristolochia plants.
    Schmeiser HH; Stiborovà M; Arlt VM
    Curr Opin Drug Discov Devel; 2009 Jan; 12(1):141-8. PubMed ID: 19152223
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Carcinogenic aristolochic acids upon activation by DT-diaphorase form adducts found in DNA of patients with Chinese herbs nephropathy.
    Stiborová M; Frei E; Sopko B; Wiessler M; Schmeiser HH
    Carcinogenesis; 2002 Apr; 23(4):617-25. PubMed ID: 11960915
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Dicoumarol inhibits rat NAD(P)H:quinone oxidoreductase in vitro and induces its expression in vivo.
    Stiborova M; Levova K; Barta F; Dracinska H; Sulc M; Hodek P; Frei E; Arlt VM; Schmeiser HH
    Neuro Endocrinol Lett; 2014; 35 Suppl 2():123-32. PubMed ID: 25638376
    [TBL] [Abstract][Full Text] [Related]  

  • 34. The impact of p53 on aristolochic acid I-induced nephrotoxicity and DNA damage in vivo and in vitro.
    Sborchia M; De Prez EG; Antoine MH; Bienfait L; Indra R; Valbuena G; Phillips DH; Nortier JL; Stiborová M; Keun HC; Arlt VM
    Arch Toxicol; 2019 Nov; 93(11):3345-3366. PubMed ID: 31602497
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Human hepatic and renal microsomes, cytochromes P450 1A1/2, NADPH:cytochrome P450 reductase and prostaglandin H synthase mediate the formation of aristolochic acid-DNA adducts found in patients with urothelial cancer.
    Stiborová M; Frei E; Hodek P; Wiessler M; Schmeiser HH
    Int J Cancer; 2005 Jan; 113(2):189-97. PubMed ID: 15386410
    [TBL] [Abstract][Full Text] [Related]  

  • 36. 32P-postlabelling analysis of the DNA adducts formed by aristolochic acid I and II.
    Pfau W; Schmeiser HH; Wiessler M
    Carcinogenesis; 1990 Sep; 11(9):1627-33. PubMed ID: 2401053
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Aristolochic acid mutagenesis: molecular clues to the aetiology of Balkan endemic nephropathy-associated urothelial cancer.
    Arlt VM; Stiborová M; vom Brocke J; Simões ML; Lord GM; Nortier JL; Hollstein M; Phillips DH; Schmeiser HH
    Carcinogenesis; 2007 Nov; 28(11):2253-61. PubMed ID: 17434925
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Metabolic activation of carcinogenic aristolochic acid, a risk factor for Balkan endemic nephropathy.
    Stiborová M; Frei E; Arlt VM; Schmeiser HH
    Mutat Res; 2008; 658(1-2):55-67. PubMed ID: 17851120
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Differential comparison of genotoxic effects of aristolochic acid I and II in human cells by the mass spectroscopic quantification of γ-H2AX.
    Qu M; Xu H; Chen J; Xu B; Li Z; Ma B; Guo L; Ye Q; Xie J
    Toxicol In Vitro; 2022 Jun; 81():105349. PubMed ID: 35307501
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Role of P450 1A1 and P450 1A2 in bioactivation versus detoxication of the renal carcinogen aristolochic acid I: studies in Cyp1a1-/-, Cyp1a2-/-, and Cyp1a1/1a2-/- mice.
    Arlt VM; Levová K; Bárta F; Shi Z; Evans JD; Frei E; Schmeiser HH; Nebert DW; Phillips DH; Stiborová M
    Chem Res Toxicol; 2011 Oct; 24(10):1710-9. PubMed ID: 21932800
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 17.