532 related articles for article (PubMed ID: 34641324)
1. The Design, Synthesis, and Biological Activities of Pyrrole-Based Carboxamides: The Novel Tubulin Inhibitors Targeting the Colchicine-Binding Site.
Boichuk S; Galembikova A; Syuzov K; Dunaev P; Bikinieva F; Aukhadieva A; Zykova S; Igidov N; Gankova K; Novikova M; Kopnin P
Molecules; 2021 Sep; 26(19):. PubMed ID: 34641324
[TBL] [Abstract][Full Text] [Related]
2. Computational-Based Discovery of the Anti-Cancer Activities of Pyrrole-Based Compounds Targeting the Colchicine-Binding Site of Tubulin.
Boichuk S; Syuzov K; Bikinieva F; Galembikova A; Zykova S; Gankova K; Igidov S; Igidov N
Molecules; 2022 Apr; 27(9):. PubMed ID: 35566235
[TBL] [Abstract][Full Text] [Related]
3. Design and discovery of new antiproliferative 1,2,4-triazin-3(2H)-ones as tubulin polymerization inhibitors targeting colchicine binding site.
Eissa IH; Dahab MA; Ibrahim MK; Alsaif NA; Alanazi AZ; Eissa SI; Mehany ABM; Beauchemin AM
Bioorg Chem; 2021 Jul; 112():104965. PubMed ID: 34020238
[TBL] [Abstract][Full Text] [Related]
4. 2-APCAs, the Novel Microtubule Targeting Agents Active Against Distinct Cancer Cell Lines.
Boichuk S; Galembikova A; Bikinieva F; Dunaev P; Aukhadieva A; Syuzov K; Zykova S; Igidov N; Ksenofontov A; Bocharov P
Molecules; 2021 Jan; 26(3):. PubMed ID: 33503939
[TBL] [Abstract][Full Text] [Related]
5. Design, synthesis and biological evaluation of a novel tubulin inhibitor 7a3 targeting the colchicine binding site.
Lai Q; Wang Y; Wang R; Lai W; Tang L; Tao Y; Liu Y; Zhang R; Huang L; Xiang H; Zeng S; Gou L; Chen H; Yao Y; Yang J
Eur J Med Chem; 2018 Aug; 156():162-179. PubMed ID: 30006162
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and Preclinical Evaluation of Indole Triazole Conjugates as Microtubule Targeting Agents that are Effective against MCF-7 Breast Cancer Cell Lines.
Yele V; Pindiprolu SKSS; Sana S; Ramamurty DSVNM; Madasi JRK; Vadlamani S
Anticancer Agents Med Chem; 2021; 21(8):1047-1055. PubMed ID: 32981511
[TBL] [Abstract][Full Text] [Related]
7. A facile synthesis of diaryl pyrroles led to the discovery of potent colchicine site antimitotic agents.
Romagnoli R; Oliva P; Salvador MK; Manfredini S; Padroni C; Brancale A; Ferla S; Hamel E; Ronca R; Maccarinelli F; Rruga F; Mariotto E; Viola G; Bortolozzi R
Eur J Med Chem; 2021 Mar; 214():113229. PubMed ID: 33550186
[TBL] [Abstract][Full Text] [Related]
8. Design, synthesis and bioevaluation of 2,7-diaryl-pyrazolo[1,5-a]pyrimidines as tubulin polymerization inhibitors.
Liu R; Zhang S; Huang M; Guo Z; Li L; Li M; Wu L; Guan Q; Zhang W
Bioorg Chem; 2021 Oct; 115():105220. PubMed ID: 34352709
[TBL] [Abstract][Full Text] [Related]
9. Identification and optimization of biphenyl derivatives as novel tubulin inhibitors targeting colchicine-binding site overcoming multidrug resistance.
Cheng B; Zhu G; Meng L; Wu G; Chen Q; Ma S
Eur J Med Chem; 2022 Jan; 228():113930. PubMed ID: 34794817
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and Biological Evaluations of 1,2-Diaryl Pyrroles as Analogues of Combretastatin A-4.
Sun J; Chen L; Liu C; Wang Z; Zuo D; Pan J; Qi H; Bao K; Wu Y; Zhang W
Chem Biol Drug Des; 2015 Dec; 86(6):1541-7. PubMed ID: 26202587
[TBL] [Abstract][Full Text] [Related]
11. Design, synthesis and bioevaluation of 6-aryl-1-(3,4,5-trimethoxyphenyl)-1H-benzo[d]imidazoles as tubulin polymerization inhibitors.
Liu R; Huang M; Zhang S; Li L; Li M; Sun J; Wu L; Guan Q; Zhang W
Eur J Med Chem; 2021 Dec; 226():113826. PubMed ID: 34571171
[TBL] [Abstract][Full Text] [Related]
12. A novel orally active microtubule destabilizing agent S-40 targets the colchicine-binding site and shows potent antitumor activity.
Du T; Lin S; Ji M; Xue N; Liu Y; Zhang Z; Zhang K; Zhang J; Zhang Y; Wang Q; Sheng L; Li Y; Lu D; Chen X; Xu H
Cancer Lett; 2020 Dec; 495():22-32. PubMed ID: 32931884
[TBL] [Abstract][Full Text] [Related]
13. Discovery of new quinolines as potent colchicine binding site inhibitors: design, synthesis, docking studies, and anti-proliferative evaluation.
Hagras M; El Deeb MA; Elzahabi HSA; Elkaeed EB; Mehany ABM; Eissa IH
J Enzyme Inhib Med Chem; 2021 Dec; 36(1):640-658. PubMed ID: 33588683
[TBL] [Abstract][Full Text] [Related]
14. 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition.
Romagnoli R; Kimatrai Salvador M; Schiaffino Ortega S; Baraldi PG; Oliva P; Baraldi S; Lopez-Cara LC; Brancale A; Ferla S; Hamel E; Balzarini J; Liekens S; Mattiuzzo E; Basso G; Viola G
Eur J Med Chem; 2018 Jan; 143():683-698. PubMed ID: 29220790
[TBL] [Abstract][Full Text] [Related]
15. Design, Synthesis, and Biological Evaluation of 1-Methyl-1,4-dihydroindeno[1,2-c]pyrazole Analogues as Potential Anticancer Agents Targeting Tubulin Colchicine Binding Site.
Liu YN; Wang JJ; Ji YT; Zhao GD; Tang LQ; Zhang CM; Guo XL; Liu ZP
J Med Chem; 2016 Jun; 59(11):5341-55. PubMed ID: 27172319
[TBL] [Abstract][Full Text] [Related]
16. New pyrrole derivatives with potent tubulin polymerization inhibiting activity as anticancer agents including hedgehog-dependent cancer.
La Regina G; Bai R; Coluccia A; Famiglini V; Pelliccia S; Passacantilli S; Mazzoccoli C; Ruggieri V; Sisinni L; Bolognesi A; Rensen WM; Miele A; Nalli M; Alfonsi R; Di Marcotullio L; Gulino A; Brancale A; Novellino E; Dondio G; Vultaggio S; Varasi M; Mercurio C; Hamel E; Lavia P; Silvestri R
J Med Chem; 2014 Aug; 57(15):6531-52. PubMed ID: 25025991
[TBL] [Abstract][Full Text] [Related]
17. Design, synthesis, and biological evaluation of new series of pyrrol-2(3H)-one and pyridazin-3(2H)-one derivatives as tubulin polymerization inhibitors.
Abdelbaset MS; Abdelrahman MH; Bukhari SNA; Gouda AM; Youssif BGM; Abdel-Aziz M; Abuo-Rahma GEA
Bioorg Chem; 2021 Feb; 107():104522. PubMed ID: 33317838
[TBL] [Abstract][Full Text] [Related]
18. Design and synthesis of (2-(phenylamino)thieno[3,2-d]pyrimidin-4-yl)(3,4,5-trimethoxyphenyl)methanone analogues as potent anti-tubulin polymerization agents.
Tian C; Chen X; Zhang Z; Wang X; Liu J
Eur J Med Chem; 2019 Dec; 183():111679. PubMed ID: 31541870
[TBL] [Abstract][Full Text] [Related]
19. The discovery of novel indazole derivatives as tubulin colchicine site binding agents that displayed potent antitumor activity both in vitro and in vivo.
Cui YJ; Ma CC; Zhang CM; Tang LQ; Liu ZP
Eur J Med Chem; 2020 Feb; 187():111968. PubMed ID: 31865012
[TBL] [Abstract][Full Text] [Related]
20. Design, synthesis and evaluation of novel bis-substituted aromatic amide dithiocarbamate derivatives as colchicine site tubulin polymerization inhibitors with potent anticancer activities.
Sun YX; Song J; Kong LJ; Sha BB; Tian XY; Liu XJ; Hu T; Chen P; Zhang SY
Eur J Med Chem; 2022 Feb; 229():114069. PubMed ID: 34971875
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]