BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

181 related articles for article (PubMed ID: 34642093)

  • 1. ADAR1 entraps sinister cellular dsRNAs, thresholding antiviral responses.
    Keegan LP; Vukić D; O'Connell MA
    Trends Immunol; 2021 Nov; 42(11):953-955. PubMed ID: 34642093
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The RNA-editing enzyme ADAR1: a regulatory hub that tunes multiple dsRNA-sensing pathways.
    Nakahama T; Kawahara Y
    Int Immunol; 2023 Mar; 35(3):123-133. PubMed ID: 36469491
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ADAR1 interaction with Z-RNA promotes editing of endogenous double-stranded RNA and prevents MDA5-dependent immune activation.
    de Reuver R; Dierick E; Wiernicki B; Staes K; Seys L; De Meester E; Muyldermans T; Botzki A; Lambrecht BN; Van Nieuwerburgh F; Vandenabeele P; Maelfait J
    Cell Rep; 2021 Aug; 36(6):109500. PubMed ID: 34380029
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mutations in the adenosine deaminase ADAR1 that prevent endogenous Z-RNA binding induce Aicardi-Goutières-syndrome-like encephalopathy.
    Nakahama T; Kato Y; Shibuya T; Inoue M; Kim JI; Vongpipatana T; Todo H; Xing Y; Kawahara Y
    Immunity; 2021 Sep; 54(9):1976-1988.e7. PubMed ID: 34525338
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The RNA-editing enzyme ADAR1 controls innate immune responses to RNA.
    Mannion NM; Greenwood SM; Young R; Cox S; Brindle J; Read D; Nellåker C; Vesely C; Ponting CP; McLaughlin PJ; Jantsch MF; Dorin J; Adams IR; Scadden AD; Ohman M; Keegan LP; O'Connell MA
    Cell Rep; 2014 Nov; 9(4):1482-94. PubMed ID: 25456137
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Deciphering the Biological Significance of ADAR1-Z-RNA Interactions.
    Nakahama T; Kawahara Y
    Int J Mol Sci; 2021 Oct; 22(21):. PubMed ID: 34768866
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Aicardi-Goutières syndrome-associated mutation at ADAR1 gene locus activates innate immune response in mouse brain.
    Guo X; Wiley CA; Steinman RA; Sheng Y; Ji B; Wang J; Zhang L; Wang T; Zenatai M; Billiar TR; Wang Q
    J Neuroinflammation; 2021 Jul; 18(1):169. PubMed ID: 34332594
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Adenosine-to-inosine editing of endogenous Z-form RNA by the deaminase ADAR1 prevents spontaneous MAVS-dependent type I interferon responses.
    Tang Q; Rigby RE; Young GR; Hvidt AK; Davis T; Tan TK; Bridgeman A; Townsend AR; Kassiotis G; Rehwinkel J
    Immunity; 2021 Sep; 54(9):1961-1975.e5. PubMed ID: 34525337
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown.
    Chung H; Calis JJA; Wu X; Sun T; Yu Y; Sarbanes SL; Dao Thi VL; Shilvock AR; Hoffmann HH; Rosenberg BR; Rice CM
    Cell; 2018 Feb; 172(4):811-824.e14. PubMed ID: 29395325
    [TBL] [Abstract][Full Text] [Related]  

  • 10. ADAR1 prevents autoinflammation by suppressing spontaneous ZBP1 activation.
    de Reuver R; Verdonck S; Dierick E; Nemegeer J; Hessmann E; Ahmad S; Jans M; Blancke G; Van Nieuwerburgh F; Botzki A; Vereecke L; van Loo G; Declercq W; Hur S; Vandenabeele P; Maelfait J
    Nature; 2022 Jul; 607(7920):784-789. PubMed ID: 35859175
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The role of RNA editing enzyme ADAR1 in human disease.
    Song B; Shiromoto Y; Minakuchi M; Nishikura K
    Wiley Interdiscip Rev RNA; 2022 Jan; 13(1):e1665. PubMed ID: 34105255
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ADAR RNA Modifications, the Epitranscriptome and Innate Immunity.
    Quin J; Sedmík J; Vukić D; Khan A; Keegan LP; O'Connell MA
    Trends Biochem Sci; 2021 Sep; 46(9):758-771. PubMed ID: 33736931
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature.
    Rice GI; Kasher PR; Forte GM; Mannion NM; Greenwood SM; Szynkiewicz M; Dickerson JE; Bhaskar SS; Zampini M; Briggs TA; Jenkinson EM; Bacino CA; Battini R; Bertini E; Brogan PA; Brueton LA; Carpanelli M; De Laet C; de Lonlay P; del Toro M; Desguerre I; Fazzi E; Garcia-Cazorla A; Heiberg A; Kawaguchi M; Kumar R; Lin JP; Lourenco CM; Male AM; Marques W; Mignot C; Olivieri I; Orcesi S; Prabhakar P; Rasmussen M; Robinson RA; Rozenberg F; Schmidt JL; Steindl K; Tan TY; van der Merwe WG; Vanderver A; Vassallo G; Wakeling EL; Wassmer E; Whittaker E; Livingston JH; Lebon P; Suzuki T; McLaughlin PJ; Keegan LP; O'Connell MA; Lovell SC; Crow YJ
    Nat Genet; 2012 Nov; 44(11):1243-8. PubMed ID: 23001123
    [TBL] [Abstract][Full Text] [Related]  

  • 14. ADAR1 Zα domain P195A mutation activates the MDA5-dependent RNA-sensing signaling pathway in brain without decreasing overall RNA editing.
    Guo X; Liu S; Sheng Y; Zenati M; Billiar T; Herbert A; Wang Q
    Cell Rep; 2023 Jul; 42(7):112733. PubMed ID: 37421629
    [TBL] [Abstract][Full Text] [Related]  

  • 15. ADAR RNA editing in innate immune response phasing, in circadian clocks and in sleep.
    Sinigaglia K; Wiatrek D; Khan A; Michalik D; Sambrani N; Sedmík J; Vukić D; O'Connell MA; Keegan LP
    Biochim Biophys Acta Gene Regul Mech; 2019 Mar; 1862(3):356-369. PubMed ID: 30391332
    [TBL] [Abstract][Full Text] [Related]  

  • 16. ADAR1 edits the SenZ and SenZ-ability of RNA.
    Zillinger T; Bartok E
    Immunity; 2021 Sep; 54(9):1909-1911. PubMed ID: 34525334
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The phenotype of the most common human ADAR1p150 Zα mutation P193A in mice is partially penetrant.
    Liang Z; Chalk AM; Taylor S; Goradia A; Heraud-Farlow JE; Walkley CR
    EMBO Rep; 2023 May; 24(5):e55835. PubMed ID: 36975179
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The ADAR1 editome reveals drivers of editing-specificity for ADAR1-isoforms.
    Kleinova R; Rajendra V; Leuchtenberger AF; Lo Giudice C; Vesely C; Kapoor U; Tanzer A; Derdak S; Picardi E; Jantsch MF
    Nucleic Acids Res; 2023 May; 51(9):4191-4207. PubMed ID: 37026479
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ADAR1p150 prevents MDA5 and PKR activation via distinct mechanisms to avert fatal autoinflammation.
    Hu SB; Heraud-Farlow J; Sun T; Liang Z; Goradia A; Taylor S; Walkley CR; Li JB
    Mol Cell; 2023 Nov; 83(21):3869-3884.e7. PubMed ID: 37797622
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Impact of Disease-Associated Mutations on the Deaminase Activity of ADAR1.
    Karki A; Campbell KB; Mozumder S; Fisher AJ; Beal PA
    Biochemistry; 2024 Feb; 63(3):282-293. PubMed ID: 38190734
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.