These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Flecainide exerts paradoxical effects on sodium currents and atrial arrhythmia in murine RyR2-P2328S hearts. Salvage SC; King JH; Chandrasekharan KH; Jafferji DI; Guzadhur L; Matthews HR; Huang CL; Fraser JA Acta Physiol (Oxf); 2015 Jul; 214(3):361-75. PubMed ID: 25850710 [TBL] [Abstract][Full Text] [Related]
3. RYR2 Channel Inhibition Is the Principal Mechanism of Flecainide Action in CPVT. Kryshtal DO; Blackwell DJ; Egly CL; Smith AN; Batiste SM; Johnston JN; Laver DR; Knollmann BC Circ Res; 2021 Feb; 128(3):321-331. PubMed ID: 33297863 [TBL] [Abstract][Full Text] [Related]
4. How does flecainide impact RyR2 channel function? Salvage SC; Huang CL; Fraser JA; Dulhunty AF J Gen Physiol; 2022 Sep; 154(9):. PubMed ID: 35713932 [TBL] [Abstract][Full Text] [Related]
5. Feedback contributions to excitation-contraction coupling in native functioning striated muscle. Salvage SC; Dulhunty AF; Jeevaratnam K; Jackson AP; Huang CL Philos Trans R Soc Lond B Biol Sci; 2023 Jun; 378(1879):20220162. PubMed ID: 37122213 [TBL] [Abstract][Full Text] [Related]
6. The RyR2-P2328S mutation downregulates Nav1.5 producing arrhythmic substrate in murine ventricles. Ning F; Luo L; Ahmad S; Valli H; Jeevaratnam K; Wang T; Guzadhur L; Yang D; Fraser JA; Huang CL; Ma A; Salvage SC Pflugers Arch; 2016 Apr; 468(4):655-65. PubMed ID: 26545784 [TBL] [Abstract][Full Text] [Related]
7. The mechanism of flecainide action in CPVT does not involve a direct effect on RyR2. Bannister ML; Thomas NL; Sikkel MB; Mukherjee S; Maxwell C; MacLeod KT; George CH; Williams AJ Circ Res; 2015 Apr; 116(8):1324-35. PubMed ID: 25648700 [TBL] [Abstract][Full Text] [Related]
8. Calcium leak through ryanodine receptors leads to atrial fibrillation in 3 mouse models of catecholaminergic polymorphic ventricular tachycardia. Shan J; Xie W; Betzenhauser M; Reiken S; Chen BX; Wronska A; Marks AR Circ Res; 2012 Aug; 111(6):708-17. PubMed ID: 22828895 [TBL] [Abstract][Full Text] [Related]