304 related articles for article (PubMed ID: 34643468)
1. DYNC1LI2 regulates localization of the chaperone-mediated autophagy receptor LAMP2A and improves cellular homeostasis in cystinosis.
Rahman F; Johnson JL; Zhang J; He J; Pestonjamasp K; Cherqui S; Catz SD
Autophagy; 2022 May; 18(5):1108-1126. PubMed ID: 34643468
[TBL] [Abstract][Full Text] [Related]
2. Cystinosin, the small GTPase Rab11, and the Rab7 effector RILP regulate intracellular trafficking of the chaperone-mediated autophagy receptor LAMP2A.
Zhang J; Johnson JL; He J; Napolitano G; Ramadass M; Rocca C; Kiosses WB; Bucci C; Xin Q; Gavathiotis E; Cuervo AM; Cherqui S; Catz SD
J Biol Chem; 2017 Jun; 292(25):10328-10346. PubMed ID: 28465352
[TBL] [Abstract][Full Text] [Related]
3. Chaperone-Mediated Autophagy Upregulation Rescues Megalin Expression and Localization in Cystinotic Proximal Tubule Cells.
Zhang J; He J; Johnson JL; Rahman F; Gavathiotis E; Cuervo AM; Catz SD
Front Endocrinol (Lausanne); 2019; 10():21. PubMed ID: 30774622
[TBL] [Abstract][Full Text] [Related]
4. Impairment of chaperone-mediated autophagy leads to selective lysosomal degradation defects in the lysosomal storage disease cystinosis.
Napolitano G; Johnson JL; He J; Rocca CJ; Monfregola J; Pestonjamasp K; Cherqui S; Catz SD
EMBO Mol Med; 2015 Feb; 7(2):158-74. PubMed ID: 25586965
[TBL] [Abstract][Full Text] [Related]
5. Upregulation of the Rab27a-dependent trafficking and secretory mechanisms improves lysosomal transport, alleviates endoplasmic reticulum stress, and reduces lysosome overload in cystinosis.
Johnson JL; Napolitano G; Monfregola J; Rocca CJ; Cherqui S; Catz SD
Mol Cell Biol; 2013 Aug; 33(15):2950-62. PubMed ID: 23716592
[TBL] [Abstract][Full Text] [Related]
6. Protection of Cystinotic Mice by Kidney-Specific Megalin Ablation Supports an Endocytosis-Based Mechanism for Nephropathic Cystinosis Progression.
Janssens V; Gaide Chevronnay HP; Marie S; Vincent MF; Van Der Smissen P; Nevo N; Vainio S; Nielsen R; Christensen EI; Jouret F; Antignac C; Pierreux CE; Courtoy PJ
J Am Soc Nephrol; 2019 Nov; 30(11):2177-2190. PubMed ID: 31548351
[TBL] [Abstract][Full Text] [Related]
7. Impaired degradation of YAP1 and IL6ST by chaperone-mediated autophagy promotes proliferation and migration of normal and hepatocellular carcinoma cells.
Desideri E; Castelli S; Dorard C; Toifl S; Grazi GL; Ciriolo MR; Baccarini M
Autophagy; 2023 Jan; 19(1):152-162. PubMed ID: 35435804
[TBL] [Abstract][Full Text] [Related]
8. Cell-Based Phenotypic Drug Screening Identifies Luteolin as Candidate Therapeutic for Nephropathic Cystinosis.
De Leo E; Elmonem MA; Berlingerio SP; Berquez M; Festa BP; Raso R; Bellomo F; Starborg T; Janssen MJ; Abbaszadeh Z; Cairoli S; Goffredo BM; Masereeuw R; Devuyst O; Lowe M; Levtchenko E; Luciani A; Emma F; Rega LR
J Am Soc Nephrol; 2020 Jul; 31(7):1522-1537. PubMed ID: 32503896
[TBL] [Abstract][Full Text] [Related]
9. Transcription factor NFE2L2/NRF2 modulates chaperone-mediated autophagy through the regulation of LAMP2A.
Pajares M; Rojo AI; Arias E; Díaz-Carretero A; Cuervo AM; Cuadrado A
Autophagy; 2018; 14(8):1310-1322. PubMed ID: 29950142
[TBL] [Abstract][Full Text] [Related]
10. Activation of the transcription factor EB rescues lysosomal abnormalities in cystinotic kidney cells.
Rega LR; Polishchuk E; Montefusco S; Napolitano G; Tozzi G; Zhang J; Bellomo F; Taranta A; Pastore A; Polishchuk R; Piemonte F; Medina DL; Catz SD; Ballabio A; Emma F
Kidney Int; 2016 Apr; 89(4):862-73. PubMed ID: 26994576
[TBL] [Abstract][Full Text] [Related]
11. Chaperone-mediated autophagy protects against hyperglycemic stress.
Vélez EJ; Schnebert S; Goguet M; Balbuena-Pecino S; Dias K; Beauclair L; Fontagné-Dicharry S; Véron V; Depincé A; Beaumatin F; Herpin A; Seiliez I
Autophagy; 2024 Apr; 20(4):752-768. PubMed ID: 37798944
[TBL] [Abstract][Full Text] [Related]
12. A mouse model suggests two mechanisms for thyroid alterations in infantile cystinosis: decreased thyroglobulin synthesis due to endoplasmic reticulum stress/unfolded protein response and impaired lysosomal processing.
Gaide Chevronnay HP; Janssens V; Van Der Smissen P; Liao XH; Abid Y; Nevo N; Antignac C; Refetoff S; Cherqui S; Pierreux CE; Courtoy PJ
Endocrinology; 2015 Jun; 156(6):2349-64. PubMed ID: 25811319
[TBL] [Abstract][Full Text] [Related]
13. Recruitment of dynein to late endosomes and lysosomes through light intermediate chains.
Tan SC; Scherer J; Vallee RB
Mol Biol Cell; 2011 Feb; 22(4):467-77. PubMed ID: 21169557
[TBL] [Abstract][Full Text] [Related]
14. The lysosomal membrane protein LAMP2A promotes autophagic flux and prevents SNCA-induced Parkinson disease-like symptoms in the Drosophila brain.
Issa AR; Sun J; Petitgas C; Mesquita A; Dulac A; Robin M; Mollereau B; Jenny A; Chérif-Zahar B; Birman S
Autophagy; 2018; 14(11):1898-1910. PubMed ID: 29989488
[TBL] [Abstract][Full Text] [Related]
15. Age-dependent accumulation of oligomeric SNCA/α-synuclein from impaired degradation in mutant LRRK2 knockin mouse model of Parkinson disease: role for therapeutic activation of chaperone-mediated autophagy (CMA).
Ho PW; Leung CT; Liu H; Pang SY; Lam CS; Xian J; Li L; Kung MH; Ramsden DB; Ho SL
Autophagy; 2020 Feb; 16(2):347-370. PubMed ID: 30983487
[TBL] [Abstract][Full Text] [Related]
16. Discovery of a potent SCAP degrader that ameliorates HFD-induced obesity, hyperlipidemia and insulin resistance via an autophagy-independent lysosomal pathway.
Zheng ZG; Zhu ST; Cheng HM; Zhang X; Cheng G; Thu PM; Wang SP; Li HJ; Ding M; Qiang L; Chen XW; Zhong Q; Li P; Xu X
Autophagy; 2021 Jul; 17(7):1592-1613. PubMed ID: 32432943
[TBL] [Abstract][Full Text] [Related]
17. Cross-regulation of defective endolysosome trafficking and enhanced autophagy through TFEB in UNC13D deficiency.
Zhang J; He J; Johnson JL; Napolitano G; Ramadass M; Rahman F; Catz SD
Autophagy; 2019 Oct; 15(10):1738-1756. PubMed ID: 30892133
[TBL] [Abstract][Full Text] [Related]
18. Chaperone-mediated autophagy protects cardiomyocytes against hypoxic-cell death.
Ghosh R; Gillaspie JJ; Campbell KS; Symons JD; Boudina S; Pattison JS
Am J Physiol Cell Physiol; 2022 Nov; 323(5):C1555-C1575. PubMed ID: 35584327
[TBL] [Abstract][Full Text] [Related]
19. Cystinosin-LKG rescues cystine accumulation and decreases apoptosis rate in cystinotic proximal tubular epithelial cells.
Taranta A; Bellomo F; Petrini S; Polishchuk E; De Leo E; Rega LR; Pastore A; Polishchuk R; De Matteis MA; Emma F
Pediatr Res; 2017 Jan; 81(1-1):113-119. PubMed ID: 27656773
[TBL] [Abstract][Full Text] [Related]
20. Bioengineered Cystinotic Kidney Tubules Recapitulate a Nephropathic Phenotype.
Sendino Garví E; Masereeuw R; Janssen MJ
Cells; 2022 Jan; 11(1):. PubMed ID: 35011739
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]