248 related articles for article (PubMed ID: 34643971)
1. Microglia-specific ApoE knock-out does not alter Alzheimer's disease plaque pathogenesis or gene expression.
Henningfield CM; Arreola MA; Soni N; Spangenberg EE; Green KN
Glia; 2022 Feb; 70(2):287-302. PubMed ID: 34643971
[TBL] [Abstract][Full Text] [Related]
2. Murine versus human apolipoprotein E4: differential facilitation of and co-localization in cerebral amyloid angiopathy and amyloid plaques in APP transgenic mouse models.
Liao F; Zhang TJ; Jiang H; Lefton KB; Robinson GO; Vassar R; Sullivan PM; Holtzman DM
Acta Neuropathol Commun; 2015 Nov; 3():70. PubMed ID: 26556230
[TBL] [Abstract][Full Text] [Related]
3. Lack of hepatic apoE does not influence early Aβ deposition: observations from a new APOE knock-in model.
Huynh TV; Wang C; Tran AC; Tabor GT; Mahan TE; Francis CM; Finn MB; Spellman R; Manis M; Tanzi RE; Ulrich JD; Holtzman DM
Mol Neurodegener; 2019 Oct; 14(1):37. PubMed ID: 31623648
[TBL] [Abstract][Full Text] [Related]
4. Human APOE4 increases microglia reactivity at Aβ plaques in a mouse model of Aβ deposition.
Rodriguez GA; Tai LM; LaDu MJ; Rebeck GW
J Neuroinflammation; 2014 Jun; 11():111. PubMed ID: 24948358
[TBL] [Abstract][Full Text] [Related]
5. Human apolipoprotein E4 alters the amyloid-beta 40:42 ratio and promotes the formation of cerebral amyloid angiopathy in an amyloid precursor protein transgenic model.
Fryer JD; Simmons K; Parsadanian M; Bales KR; Paul SM; Sullivan PM; Holtzman DM
J Neurosci; 2005 Mar; 25(11):2803-10. PubMed ID: 15772340
[TBL] [Abstract][Full Text] [Related]
6. The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases.
Krasemann S; Madore C; Cialic R; Baufeld C; Calcagno N; El Fatimy R; Beckers L; O'Loughlin E; Xu Y; Fanek Z; Greco DJ; Smith ST; Tweet G; Humulock Z; Zrzavy T; Conde-Sanroman P; Gacias M; Weng Z; Chen H; Tjon E; Mazaheri F; Hartmann K; Madi A; Ulrich JD; Glatzel M; Worthmann A; Heeren J; Budnik B; Lemere C; Ikezu T; Heppner FL; Litvak V; Holtzman DM; Lassmann H; Weiner HL; Ochando J; Haass C; Butovsky O
Immunity; 2017 Sep; 47(3):566-581.e9. PubMed ID: 28930663
[TBL] [Abstract][Full Text] [Related]
7. Fibrillar Aβ triggers microglial proteome alterations and dysfunction in Alzheimer mouse models.
Sebastian Monasor L; Müller SA; Colombo AV; Tanrioever G; König J; Roth S; Liesz A; Berghofer A; Piechotta A; Prestel M; Saito T; Saido TC; Herms J; Willem M; Haass C; Lichtenthaler SF; Tahirovic S
Elife; 2020 Jun; 9():. PubMed ID: 32510331
[TBL] [Abstract][Full Text] [Related]
8. Selective reduction of astrocyte apoE3 and apoE4 strongly reduces Aβ accumulation and plaque-related pathology in a mouse model of amyloidosis.
Mahan TE; Wang C; Bao X; Choudhury A; Ulrich JD; Holtzman DM
Mol Neurodegener; 2022 Feb; 17(1):13. PubMed ID: 35109920
[TBL] [Abstract][Full Text] [Related]
9. ApoE facilitates the microglial response to amyloid plaque pathology.
Ulrich JD; Ulland TK; Mahan TE; Nyström S; Nilsson KP; Song WM; Zhou Y; Reinartz M; Choi S; Jiang H; Stewart FR; Anderson E; Wang Y; Colonna M; Holtzman DM
J Exp Med; 2018 Apr; 215(4):1047-1058. PubMed ID: 29483128
[TBL] [Abstract][Full Text] [Related]
10. Human apolipoprotein E redistributes fibrillar amyloid deposition in Tg-SwDI mice.
Xu F; Vitek MP; Colton CA; Previti ML; Gharkholonarehe N; Davis J; Van Nostrand WE
J Neurosci; 2008 May; 28(20):5312-20. PubMed ID: 18480287
[TBL] [Abstract][Full Text] [Related]
11. Microglia contributes to plaque growth by cell death due to uptake of amyloid β in the brain of Alzheimer's disease mouse model.
Baik SH; Kang S; Son SM; Mook-Jung I
Glia; 2016 Dec; 64(12):2274-2290. PubMed ID: 27658617
[TBL] [Abstract][Full Text] [Related]
12. Knock-in models related to Alzheimer's disease: synaptic transmission, plaques and the role of microglia.
Benitez DP; Jiang S; Wood J; Wang R; Hall CM; Peerboom C; Wong N; Stringer KM; Vitanova KS; Smith VC; Joshi D; Saito T; Saido TC; Hardy J; Hanrieder J; De Strooper B; Salih DA; Tripathi T; Edwards FA; Cummings DM
Mol Neurodegener; 2021 Jul; 16(1):47. PubMed ID: 34266459
[TBL] [Abstract][Full Text] [Related]
13. Lack of LDL receptor enhances amyloid deposition and decreases glial response in an Alzheimer's disease mouse model.
Katsouri L; Georgopoulos S
PLoS One; 2011; 6(7):e21880. PubMed ID: 21755005
[TBL] [Abstract][Full Text] [Related]
14. Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE.
Parhizkar S; Arzberger T; Brendel M; Kleinberger G; Deussing M; Focke C; Nuscher B; Xiong M; Ghasemigharagoz A; Katzmarski N; Krasemann S; Lichtenthaler SF; Müller SA; Colombo A; Monasor LS; Tahirovic S; Herms J; Willem M; Pettkus N; Butovsky O; Bartenstein P; Edbauer D; Rominger A; Ertürk A; Grathwohl SA; Neher JJ; Holtzman DM; Meyer-Luehmann M; Haass C
Nat Neurosci; 2019 Feb; 22(2):191-204. PubMed ID: 30617257
[TBL] [Abstract][Full Text] [Related]
15. Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aβ42:Aβ40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mouse Model.
Meilandt WJ; Ngu H; Gogineni A; Lalehzadeh G; Lee SH; Srinivasan K; Imperio J; Wu T; Weber M; Kruse AJ; Stark KL; Chan P; Kwong M; Modrusan Z; Friedman BA; Elstrott J; Foreman O; Easton A; Sheng M; Hansen DV
J Neurosci; 2020 Feb; 40(9):1956-1974. PubMed ID: 31980586
[No Abstract] [Full Text] [Related]
16. Microglia prevent beta-amyloid plaque formation in the early stage of an Alzheimer's disease mouse model with suppression of glymphatic clearance.
Feng W; Zhang Y; Wang Z; Xu H; Wu T; Marshall C; Gao J; Xiao M
Alzheimers Res Ther; 2020 Oct; 12(1):125. PubMed ID: 33008458
[TBL] [Abstract][Full Text] [Related]
17. Microglia depletion rapidly and reversibly alters amyloid pathology by modification of plaque compaction and morphologies.
Casali BT; MacPherson KP; Reed-Geaghan EG; Landreth GE
Neurobiol Dis; 2020 Aug; 142():104956. PubMed ID: 32479996
[TBL] [Abstract][Full Text] [Related]
18. APP Regulates Microglial Phenotype in a Mouse Model of Alzheimer's Disease.
Manocha GD; Floden AM; Rausch K; Kulas JA; McGregor BA; Rojanathammanee L; Puig KR; Puig KL; Karki S; Nichols MR; Darland DC; Porter JE; Combs CK
J Neurosci; 2016 Aug; 36(32):8471-86. PubMed ID: 27511018
[TBL] [Abstract][Full Text] [Related]
19. Astrocytic APOE4 removal confers cerebrovascular protection despite increased cerebral amyloid angiopathy.
Xiong M; Wang C; Gratuze M; Saadi F; Bao X; Bosch ME; Lee C; Jiang H; Serrano JR; Gonzales ER; Kipnis M; Holtzman DM
Mol Neurodegener; 2023 Mar; 18(1):17. PubMed ID: 36922879
[TBL] [Abstract][Full Text] [Related]
20. The effect of amyloid on microglia-neuron interactions before plaque onset occurs independently of TREM2 in a mouse model of Alzheimer's disease.
von Saucken VE; Jay TR; Landreth GE
Neurobiol Dis; 2020 Nov; 145():105072. PubMed ID: 32890775
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
