These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

204 related articles for article (PubMed ID: 34653770)

  • 21. Cell Type-Dependent Escape of Capsid Inhibitors by Simian Immunodeficiency Virus SIVcpz.
    Twizerimana AP; Scheck R; Becker D; Zhang Z; Wammers M; Avelar L; Pflieger M; Häussinger D; Kurz T; Gohlke H; Münk C
    J Virol; 2020 Nov; 94(23):. PubMed ID: 32907979
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Design, Synthesis, and Mechanistic Study of 2-Pyridone-Bearing Phenylalanine Derivatives as Novel HIV Capsid Modulators.
    Zhang X; Sun L; Xu S; Shao X; Li Z; Ding D; Jiang X; Zhao S; Cocklin S; Clercq E; Pannecouque C; Dick A; Liu X; Zhan P
    Molecules; 2022 Nov; 27(21):. PubMed ID: 36364467
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Rapid Optimization of the Metabolic Stability of a Human Immunodeficiency Virus Type-1 Capsid Inhibitor Using a Multistep Computational Workflow.
    Meuser ME; Reddy PAN; Dick A; Maurancy JM; Salvino JM; Cocklin S
    J Med Chem; 2021 Apr; 64(7):3747-3766. PubMed ID: 33750123
    [TBL] [Abstract][Full Text] [Related]  

  • 24. PF74 and Its Novel Derivatives Stabilize Hexameric Lattice of HIV-1 Mature-Like Particles.
    Dostálková A; Škach K; Kaufman F; Křížová I; Hadravová R; Flegel M; Ruml T; Hrabal R; Rumlová M
    Molecules; 2020 Apr; 25(8):. PubMed ID: 32325987
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Complementary Assays Reveal a Low Level of CA Associated with Viral Complexes in the Nuclei of HIV-1-Infected Cells.
    Hulme AE; Kelley Z; Foley D; Hope TJ
    J Virol; 2015 May; 89(10):5350-61. PubMed ID: 25741002
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Discovery of phenylalanine derivatives as potent HIV-1 capsid inhibitors from click chemistry-based compound library.
    Wu G; Zalloum WA; Meuser ME; Jing L; Kang D; Chen CH; Tian Y; Zhang F; Cocklin S; Lee KH; Liu X; Zhan P
    Eur J Med Chem; 2018 Oct; 158():478-492. PubMed ID: 30243152
    [TBL] [Abstract][Full Text] [Related]  

  • 27. PF74 Reinforces the HIV-1 Capsid To Impair Reverse Transcription-Induced Uncoating.
    Rankovic S; Ramalho R; Aiken C; Rousso I
    J Virol; 2018 Oct; 92(20):. PubMed ID: 30089694
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Off-Pathway Assembly: A Broad-Spectrum Mechanism of Action for Drugs That Undermine Controlled HIV-1 Viral Capsid Formation.
    Pak AJ; Grime JMA; Yu A; Voth GA
    J Am Chem Soc; 2019 Jul; 141(26):10214-10224. PubMed ID: 31244184
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Potency and metabolic stability: a molecular hybrid case in the design of novel PF74-like small molecules targeting HIV-1 capsid protein.
    Sahani RL; Akther T; Cilento ME; Castaner AE; Zhang H; Kirby KA; Xie J; Sarafianos SG; Wang Z
    RSC Med Chem; 2021 Dec; 12(12):2031-2044. PubMed ID: 35028563
    [TBL] [Abstract][Full Text] [Related]  

  • 30. An insight on medicinal aspects of novel HIV-1 capsid protein inhibitors.
    Sun L; Zhang X; Xu S; Huang T; Song S; Cherukupalli S; Zhan P; Liu X
    Eur J Med Chem; 2021 May; 217():113380. PubMed ID: 33751981
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Discovery of novel 1,2,4-triazole phenylalanine derivatives targeting an unexplored region within the interprotomer pocket of the HIV capsid protein.
    Jiang X; Sharma PP; Rathi B; Ji X; Hu L; Gao Z; Kang D; Wang Z; Xie M; Xu S; Zhang X; De Clercq E; Cocklin S; Pannecouque C; Dick A; Liu X; Zhan P
    J Med Virol; 2022 Dec; 94(12):5975-5986. PubMed ID: 35949003
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Functional label-free assays for characterizing the in vitro mechanism of action of small molecule modulators of capsid assembly.
    Lad L; Clancy S; Koditek D; Wong MH; Jin D; Niedziela-Majka A; Papalia GA; Hung M; Yant S; Somoza JR; Hu E; Chou C; Tse W; Halcomb R; Sakowicz R; Pagratis N
    Biochemistry; 2015 Apr; 54(13):2240-8. PubMed ID: 25774576
    [TBL] [Abstract][Full Text] [Related]  

  • 33. A Small Molecule, ACAi-028, with Anti-HIV-1 Activity Targets a Novel Hydrophobic Pocket on HIV-1 Capsid.
    Chia T; Nakamura T; Amano M; Takamune N; Matsuoka M; Nakata H
    Antimicrob Agents Chemother; 2021 Sep; 65(10):e0103921. PubMed ID: 34228546
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Design, synthesis, and mechanistic study of 2-piperazineone-bearing peptidomimetics as novel HIV capsid modulators.
    Zhang X; Sun L; Xu S; Huang T; Zhao F; Ding D; Liu C; Jiang X; Tao Y; Kang D; De Clercq E; Pannecouque C; Cocklin S; Dick A; Liu X; Zhan P
    RSC Med Chem; 2023 Jul; 14(7):1272-1295. PubMed ID: 37484571
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Synthesis of the biotinylated anti-HIV compound BMMP and the target identification study.
    Kamo M; Tateishi H; Koga R; Okamoto Y; Otsuka M; Fujita M
    Bioorg Med Chem Lett; 2016 Jan; 26(1):43-5. PubMed ID: 26615887
    [TBL] [Abstract][Full Text] [Related]  

  • 36. The discovery and design of novel HIV-1 capsid modulators and future perspectives.
    Ding D; Xu S; Zhang X; Jiang X; Cocklin S; Dick A; Zhan P; Liu X
    Expert Opin Drug Discov; 2023 Jan; 18(1):5-12. PubMed ID: 36480372
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Potent leads based on CA-19L, an anti-HIV active HIV-1 capsid fragment.
    Tsuji K; Wang R; Kobayakawa T; Owusu KB; Fujino M; Kaneko M; Yamamoto N; Murakami T; Tamamura H
    Bioorg Med Chem; 2021 Jan; 30():115923. PubMed ID: 33316719
    [TBL] [Abstract][Full Text] [Related]  

  • 38. HIV-1 CA Inhibitors Are Antagonized by Inositol Phosphate Stabilization of the Viral Capsid in Cells.
    Sowd GA; Shi J; Aiken C
    J Virol; 2021 Nov; 95(24):e0144521. PubMed ID: 34613803
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Metabolite Identification of HIV-1 Capsid Modulators PF74 and 11L in Human Liver Microsomes.
    Xu S; Sun L; Ding D; Zhang X; Liu X; Zhan P
    Metabolites; 2022 Aug; 12(8):. PubMed ID: 36005624
    [No Abstract]   [Full Text] [Related]  

  • 40. Identification of a small molecule HIV-1 inhibitor that targets the capsid hexamer.
    Xu JP; Branson JD; Lawrence R; Cocklin S
    Bioorg Med Chem Lett; 2016 Feb; 26(3):824-828. PubMed ID: 26747394
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.