136 related articles for article (PubMed ID: 34655687)
1. 4-Fluoromethamphetamine (4-FMA) induces in vitro hepatotoxicity mediated by CYP2E1, CYP2D6, and CYP3A4 metabolism.
Roque Bravo R; Carmo H; Valente MJ; Silva JP; Carvalho F; Bastos ML; Dias da Silva D
Toxicology; 2021 Nov; 463():152988. PubMed ID: 34655687
[TBL] [Abstract][Full Text] [Related]
2. The new psychoactive substance 3-methylmethcathinone (3-MMC or metaphedrone) induces oxidative stress, apoptosis, and autophagy in primary rat hepatocytes at human-relevant concentrations.
Dias da Silva D; Ferreira B; Roque Bravo R; Rebelo R; Duarte de Almeida T; Valente MJ; Silva JP; Carvalho F; Bastos ML; Carmo H
Arch Toxicol; 2019 Sep; 93(9):2617-2634. PubMed ID: 31468101
[TBL] [Abstract][Full Text] [Related]
3. From street to lab: in vitro hepatotoxicity of buphedrone, butylone and 3,4-DMMC.
Roque Bravo R; Carmo H; Valente MJ; Silva JP; Carvalho F; Bastos ML; Dias da Silva D
Arch Toxicol; 2021 Apr; 95(4):1443-1462. PubMed ID: 33550444
[TBL] [Abstract][Full Text] [Related]
4. Mechanisms of hepatocellular toxicity associated with new psychoactive synthetic cathinones.
Luethi D; Liechti ME; Krähenbühl S
Toxicology; 2017 Jul; 387():57-66. PubMed ID: 28645576
[TBL] [Abstract][Full Text] [Related]
5. In vitro evaluation of hepatotoxic drugs in human hepatocytes from multiple donors: Identification of P450 activity as a potential risk factor for drug-induced liver injuries.
Utkarsh D; Loretz C; Li AP
Chem Biol Interact; 2016 Aug; 255():12-22. PubMed ID: 26718876
[TBL] [Abstract][Full Text] [Related]
6. Emerging club drugs: 5-(2-aminopropyl)benzofuran (5-APB) is more toxic than its isomer 6-(2-aminopropyl)benzofuran (6-APB) in hepatocyte cellular models.
Roque Bravo R; Carmo H; Silva JP; Valente MJ; Carvalho F; Bastos ML; Dias da Silva D
Arch Toxicol; 2020 Feb; 94(2):609-629. PubMed ID: 31838565
[TBL] [Abstract][Full Text] [Related]
7. Exploration of components and mechanisms of Polygoni Multiflori Radix-induced hepatotoxicity using siRNA -mediated CYP3A4 or UGT1A1 knockdown liver cells.
Hu YH; Li DK; Quan ZY; Wang CY; Zhou M; Sun ZX
J Ethnopharmacol; 2021 Apr; 270():113845. PubMed ID: 33485974
[TBL] [Abstract][Full Text] [Related]
8. The role of CYP 3A4 and 1A1 in amiodarone-induced hepatocellular toxicity.
Wu Q; Ning B; Xuan J; Ren Z; Guo L; Bryant MS
Toxicol Lett; 2016 Jun; 253():55-62. PubMed ID: 27113703
[TBL] [Abstract][Full Text] [Related]
9. In vitro inhibitory effects of dihydromyricetin on human liver cytochrome P450 enzymes.
Liu L; Sun S; Rui H; Li X
Pharm Biol; 2017 Dec; 55(1):1868-1874. PubMed ID: 28614988
[TBL] [Abstract][Full Text] [Related]
10. Marsdenia tenacissima extract inhibits gefitinib metabolism in vitro by interfering with human hepatic CYP3A4 and CYP2D6 enzymes.
Han SY; Zhao HY; Zhou N; Zhou F; Li PP
J Ethnopharmacol; 2014; 151(1):210-7. PubMed ID: 24157377
[TBL] [Abstract][Full Text] [Related]
11. Sodium salicylate increases CYP2E1 levels and enhances arachidonic acid toxicity in HepG2 cells and cultured rat hepatocytes.
Wu D; Cederbaum AI
Mol Pharmacol; 2001 Apr; 59(4):795-805. PubMed ID: 11259624
[TBL] [Abstract][Full Text] [Related]
12. Mechanisms of toxicity associated with six tyrosine kinase inhibitors in human hepatocyte cell lines.
Mingard C; Paech F; Bouitbir J; Krähenbühl S
J Appl Toxicol; 2018 Mar; 38(3):418-431. PubMed ID: 29072336
[TBL] [Abstract][Full Text] [Related]
13. Evaluating the Role of Drug Metabolism and Reactive Intermediates in Trazodone-Induced Cytotoxicity toward Freshly-Isolated Rat Hepatocytes.
Najibi A; Heidari R; Zarifi J; Jamshidzadeh A; Firoozabadi N; Niknahad H
Drug Res (Stuttg); 2016 Nov; 66(11):592-596. PubMed ID: 27643409
[No Abstract] [Full Text] [Related]
14. The mechanism and risk factors of clopidogrel-induced liver injury.
Zhai Y; Wang L; Yang F; Feng G; Feng S; Cui T; An L; He X
Drug Chem Toxicol; 2016 Oct; 39(4):367-74. PubMed ID: 26654298
[TBL] [Abstract][Full Text] [Related]
15. Toward a systems approach to the human cytochrome P450 ensemble: interactions between CYP2D6 and CYP2E1 and their functional consequences.
Davydov DR; Davydova NY; Rodgers JT; Rushmore TH; Jones JP
Biochem J; 2017 Oct; 474(20):3523-3542. PubMed ID: 28904078
[TBL] [Abstract][Full Text] [Related]
16. Customised in vitro model to detect human metabolism-dependent idiosyncratic drug-induced liver injury.
Tolosa L; Jiménez N; Pérez G; Castell JV; Gómez-Lechón MJ; Donato MT
Arch Toxicol; 2018 Jan; 92(1):383-399. PubMed ID: 28762043
[TBL] [Abstract][Full Text] [Related]
17. Cytotoxic effects of psychotropic benzofuran derivatives, N-methyl-5-(2-aminopropyl)benzofuran and its N-demethylated derivative, on isolated rat hepatocytes.
Nakagawa Y; Suzuki T; Tada Y; Inomata A
J Appl Toxicol; 2017 Mar; 37(3):243-252. PubMed ID: 27291301
[TBL] [Abstract][Full Text] [Related]
18. Polysaccharide peptides from Coriolus versicolor competitively inhibit model cytochrome P450 enzyme probe substrates metabolism in human liver microsomes.
Yeung JH; Or PM
Phytomedicine; 2012 Mar; 19(5):457-63. PubMed ID: 22305191
[TBL] [Abstract][Full Text] [Related]
19. Development of an in vitro screening method of acute cytotoxicity of the pyrrolizidine alkaloid lasiocarpine in human and rodent hepatic cell lines by increasing susceptibility.
Forsch K; Schöning V; Disch L; Siewert B; Unger M; Drewe J
J Ethnopharmacol; 2018 May; 217():134-139. PubMed ID: 29454024
[TBL] [Abstract][Full Text] [Related]
20. Apoptosis in HepaRG and HL-7702 cells inducted by polyphyllin II through caspases activation and cell-cycle arrest.
Wang W; Dong X; You L; Sai N; Leng X; Yang C; Yin X; Ni J
J Cell Physiol; 2019 May; 234(5):7078-7089. PubMed ID: 30362578
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
