BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

217 related articles for article (PubMed ID: 34657603)

  • 1. Tryptophan metabolism induced by TDO2 promotes prostatic cancer chemotherapy resistance in a AhR/c-Myc dependent manner.
    Li F; Zhao Z; Zhang Z; Zhang Y; Guan W
    BMC Cancer; 2021 Oct; 21(1):1112. PubMed ID: 34657603
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A TDO2-AhR signaling axis facilitates anoikis resistance and metastasis in triple-negative breast cancer.
    D'Amato NC; Rogers TJ; Gordon MA; Greene LI; Cochrane DR; Spoelstra NS; Nemkov TG; D'Alessandro A; Hansen KC; Richer JK
    Cancer Res; 2015 Nov; 75(21):4651-64. PubMed ID: 26363006
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Kynurenine produced by tryptophan 2,3-dioxygenase metabolism promotes glioma progression through an aryl hydrocarbon receptor-dependent signaling pathway.
    Ma W; Ye L; Zhong C; Li J; Ye F; Lv L; Yu Y; Jiang S; Zhou P
    Cell Biol Int; 2022 Oct; 46(10):1577-1587. PubMed ID: 35702760
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeting of neuroblastoma cells through Kynurenine-AHR pathway inhibition.
    Dos Santos IL; Mitchell M; Nogueira PAS; Lafita-Navarro MC; Perez-Castro L; Eriom J; Kilgore JA; Williams NS; Guo L; Xu L; Conacci-Sorrell M
    FEBS J; 2024 May; 291(10):2172-2190. PubMed ID: 38431776
    [TBL] [Abstract][Full Text] [Related]  

  • 5. TDO2 and tryptophan metabolites promote kynurenine/AhR signals to facilitate glioma progression and immunosuppression.
    Zhong C; Peng L; Tao B; Yin S; Lyu L; Ding H; Yang X; Peng T; He H; Zhou P
    Am J Cancer Res; 2022; 12(6):2558-2575. PubMed ID: 35812057
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Constitutive TDO2 expression promotes liver cancer progression by an autocrine IL-6 signaling pathway.
    Wu Z; Yan L; Lin J; Ke K; Yang W
    Cancer Cell Int; 2021 Oct; 21(1):538. PubMed ID: 34657635
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hypoxia Routes Tryptophan Homeostasis Towards Increased Tryptamine Production.
    Mohapatra SR; Sadik A; Sharma S; Poschet G; Gegner HM; Lanz TV; Lucarelli P; Klingmüller U; Platten M; Heiland I; Opitz CA
    Front Immunol; 2021; 12():590532. PubMed ID: 33679737
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Reimagining IDO Pathway Inhibition in Cancer Immunotherapy via Downstream Focus on the Tryptophan-Kynurenine-Aryl Hydrocarbon Axis.
    Labadie BW; Bao R; Luke JJ
    Clin Cancer Res; 2019 Mar; 25(5):1462-1471. PubMed ID: 30377198
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Kynurenine produced by indoleamine 2,3-dioxygenase 2 exacerbates acute liver injury by carbon tetrachloride in mice.
    Hoshi M; Osawa Y; Nakamoto K; Morita N; Yamamoto Y; Ando T; Tashita C; Nabeshima T; Saito K
    Toxicology; 2020 May; 438():152458. PubMed ID: 32289347
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 1-Methyl-D-tryptophan activates aryl hydrocarbon receptor, a pathway associated with bladder cancer progression.
    Matheus LHG; Dalmazzo SV; Brito RBO; Pereira LA; de Almeida RJ; Camacho CP; Dellê H
    BMC Cancer; 2020 Sep; 20(1):869. PubMed ID: 32907554
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeting the IDO1/TDO2-KYN-AhR Pathway for Cancer Immunotherapy - Challenges and Opportunities.
    Cheong JE; Sun L
    Trends Pharmacol Sci; 2018 Mar; 39(3):307-325. PubMed ID: 29254698
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Tryptophan and its metabolites in normal physiology and cancer etiology.
    Perez-Castro L; Garcia R; Venkateswaran N; Barnes S; Conacci-Sorrell M
    FEBS J; 2023 Jan; 290(1):7-27. PubMed ID: 34687129
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Blockade of IDO-Kynurenine-AhR Axis Ameliorated Colitis-Associated Colon Cancer via Inhibiting Immune Tolerance.
    Zhang X; Liu X; Zhou W; Du Q; Yang M; Ding Y; Hu R
    Cell Mol Gastroenterol Hepatol; 2021; 12(4):1179-1199. PubMed ID: 34087454
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Stemness and immune evasion conferred by the TDO2-AHR pathway are associated with liver metastasis of colon cancer.
    Miyazaki T; Chung S; Sakai H; Ohata H; Obata Y; Shiokawa D; Mizoguchi Y; Kubo T; Ichikawa H; Taniguchi H; Aoki K; Soga T; Nakagama H; Okamoto K
    Cancer Sci; 2022 Jan; 113(1):170-181. PubMed ID: 34714577
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Indoleamine 2, 3-Dioxygenase 1 Mediates Survival Signals in Chronic Lymphocytic Leukemia
    Atene CG; Fiorcari S; Mesini N; Alboni S; Martinelli S; Maccaferri M; Leonardi G; Potenza L; Luppi M; Maffei R; Marasca R
    Front Immunol; 2022; 13():832263. PubMed ID: 35371054
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Targeting Tryptophan Catabolism in Ovarian Cancer to Attenuate Macrophage Infiltration and PD-L1 Expression.
    Crump LS; Floyd JL; Kuo LW; Post MD; Bickerdike M; O'Neill K; Sompel K; Jordan KR; Corr BR; Marjon N; Woodruff ER; Richer JK; Bitler BG
    Cancer Res Commun; 2024 Mar; 4(3):822-833. PubMed ID: 38451784
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Investigation of the aryl hydrocarbon receptor and the intrinsic tumoral component of the kynurenine pathway of tryptophan metabolism in primary brain tumors.
    Guastella AR; Michelhaugh SK; Klinger NV; Fadel HA; Kiousis S; Ali-Fehmi R; Kupsky WJ; Juhász C; Mittal S
    J Neurooncol; 2018 Sep; 139(2):239-249. PubMed ID: 29667084
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Functional role of kynurenine and aryl hydrocarbon receptor axis in chronic rhinosinusitis with nasal polyps.
    Wang H; Do DC; Liu J; Wang B; Qu J; Ke X; Luo X; Tang HM; Tang HL; Hu C; Anderson ME; Liu Z; Gao P
    J Allergy Clin Immunol; 2018 Feb; 141(2):586-600.e6. PubMed ID: 28689792
    [TBL] [Abstract][Full Text] [Related]  

  • 19. MYC promotes tryptophan uptake and metabolism by the kynurenine pathway in colon cancer.
    Venkateswaran N; Lafita-Navarro MC; Hao YH; Kilgore JA; Perez-Castro L; Braverman J; Borenstein-Auerbach N; Kim M; Lesner NP; Mishra P; Brabletz T; Shay JW; DeBerardinis RJ; Williams NS; Yilmaz OH; Conacci-Sorrell M
    Genes Dev; 2019 Sep; 33(17-18):1236-1251. PubMed ID: 31416966
    [TBL] [Abstract][Full Text] [Related]  

  • 20. TDO2 Promotes the EMT of Hepatocellular Carcinoma Through Kyn-AhR Pathway.
    Li L; Wang T; Li S; Chen Z; Wu J; Cao W; Wo Q; Qin X; Xu J
    Front Oncol; 2020; 10():562823. PubMed ID: 33542896
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.