BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

134 related articles for article (PubMed ID: 34662125)

  • 1. Imaging Autotaxin
    Deng X; Salgado-Polo F; Shao T; Xiao Z; Van R; Chen J; Rong J; Haider A; Shao Y; Josephson L; Perrakis A; Liang SH
    J Med Chem; 2021 Oct; 64(20):15053-15068. PubMed ID: 34662125
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Positron Emission Tomography Imaging of Autotaxin in Thyroid and Breast Cancer Models Using [
    Litchfield M; Wuest M; Glubrecht D; Briard E; Auberson YP; McMullen TPW; Brindley DN; Wuest F
    Mol Pharm; 2021 Sep; 18(9):3352-3364. PubMed ID: 34319110
    [TBL] [Abstract][Full Text] [Related]  

  • 3. [
    Briard E; Joshi AD; Shanmukhappa S; Ilovich O; Auberson YP
    ChemMedChem; 2019 Aug; 14(16):1493-1502. PubMed ID: 31273951
    [TBL] [Abstract][Full Text] [Related]  

  • 4. [
    Ebrahimi E; Wuest M; Kaur J; Bhardwaj A; Gade NR; Wuest F
    Bioorg Med Chem Lett; 2023 Jun; 90():129345. PubMed ID: 37217023
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, Synthesis, and Preliminary Bioactivity Evaluation of 2,7-Substituted Carbazole Derivatives as Potent Autotaxin Inhibitors and Antitumor Agents†.
    Wang W; Zhao F; Zhao Y; Pan W; Cao P; Wu L; Wang Z; Zhao X; Zhao Y; Wang H
    Anticancer Agents Med Chem; 2019; 19(2):256-264. PubMed ID: 30173652
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis of novel 2-pyrrolidinone and pyrrolidine derivatives and study of their inhibitory activity against autotaxin enzyme.
    Gerokonstantis DT; Nikolaou A; Magkrioti C; Afantitis A; Aidinis V; Kokotos G; Moutevelis-Minakakis P
    Bioorg Med Chem; 2020 Jan; 28(2):115216. PubMed ID: 31864778
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification and Preclinical Development of a 2,5,6-Trisubstituted Fluorinated Pyridine Derivative as a Radioligand for the Positron Emission Tomography Imaging of Cannabinoid Type 2 Receptors.
    Haider A; Gobbi L; Kretz J; Ullmer C; Brink A; Honer M; Woltering TJ; Muri D; Iding H; Bürkler M; Binder M; Bartelmus C; Knuesel I; Pacher P; Herde AM; Spinelli F; Ahmed H; Atz K; Keller C; Weber M; Schibli R; Mu L; Grether U; Ametamey SM
    J Med Chem; 2020 Sep; 63(18):10287-10306. PubMed ID: 32787079
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Optimization and evaluation of novel tetrahydropyrido[4,3-d]pyrimidine derivatives as ATX inhibitors for cardiac and hepatic fibrosis.
    Jiang N; Zhou Y; Zhu M; Zhang J; Cao M; Lei H; Guo M; Gong P; Su G; Zhai X
    Eur J Med Chem; 2020 Feb; 187():111904. PubMed ID: 31806537
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure-Activity Relationship Studies of Pyridine-Based Ligands and Identification of a Fluorinated Derivative for Positron Emission Tomography Imaging of Cannabinoid Type 2 Receptors.
    Haider A; Kretz J; Gobbi L; Ahmed H; Atz K; Bürkler M; Bartelmus C; Fingerle J; Guba W; Ullmer C; Honer M; Knuesel I; Weber M; Brink A; Herde AM; Keller C; Schibli R; Mu L; Grether U; Ametamey SM
    J Med Chem; 2019 Dec; 62(24):11165-11181. PubMed ID: 31751140
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Development of two fluorine-18 labeled PET radioligands targeting PDE10A and in vivo PET evaluation in nonhuman primates.
    Stepanov V; Takano A; Nakao R; Amini N; Miura S; Hasui T; Kimura H; Taniguchi T; Halldin C
    Nucl Med Biol; 2018 Feb; 57():12-19. PubMed ID: 29223715
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis, in vivo occupancy, and radiolabeling of potent phosphodiesterase subtype-10 inhibitors as candidates for positron emission tomography imaging.
    Andrés JI; De Angelis M; Alcázar J; Iturrino L; Langlois X; Dedeurwaerdere S; Lenaerts I; Vanhoof G; Celen S; Bormans G
    J Med Chem; 2011 Aug; 54(16):5820-35. PubMed ID: 21777010
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Screening and X-ray crystal structure-based optimization of autotaxin (ENPP2) inhibitors, using a newly developed fluorescence probe.
    Kawaguchi M; Okabe T; Okudaira S; Nishimasu H; Ishitani R; Kojima H; Nureki O; Aoki J; Nagano T
    ACS Chem Biol; 2013 Aug; 8(8):1713-21. PubMed ID: 23688339
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural Basis for Inhibition of Human Autotaxin by Four Potent Compounds with Distinct Modes of Binding.
    Stein AJ; Bain G; Prodanovich P; Santini AM; Darlington J; Stelzer NM; Sidhu RS; Schaub J; Goulet L; Lonergan D; Calderon I; Evans JF; Hutchinson JH
    Mol Pharmacol; 2015 Dec; 88(6):982-92. PubMed ID: 26371182
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Development of autotaxin inhibitors: A series of tetrazole cinnamides.
    Thomson CG; Le Grand D; Dowling M; Beattie D; Elphick L; Faller M; Freeman M; Hardaker E; Head V; Hemmig R; Hill J; Lister A; Pascoe D; Rieffel S; Shrestha B; Steward O; Zink F
    Bioorg Med Chem Lett; 2021 Jan; 31():127663. PubMed ID: 33160025
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis and anti-fibrosis evaluation of imidazo[1,2-a]pyridine derivatives as potent ATX inhibitors.
    Chen Y; Lei H; Li T; Cui Y; Wang X; Cao Z; Wu H; Zhai X
    Bioorg Med Chem; 2021 Sep; 46():116362. PubMed ID: 34428714
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Development of 2-(2-(3-(4-([
    Mori W; Yamasaki T; Fujinaga M; Ogawa M; Zhang Y; Hatori A; Xie L; Kumata K; Wakizaka H; Kurihara Y; Ohkubo T; Nengaki N; Zhang MR
    J Med Chem; 2019 Jan; 62(2):688-698. PubMed ID: 30516998
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Fluorinated diaryl sulfides as serotonin transporter ligands: synthesis, structure-activity relationship study, and in vivo evaluation of fluorine-18-labeled compounds as PET imaging agents.
    Huang Y; Bae SA; Zhu Z; Guo N; Roth BL; Laruelle M
    J Med Chem; 2005 Apr; 48(7):2559-70. PubMed ID: 15801845
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Recent advances in positron emission tomography (PET) radiotracers for imaging phosphodiesterases.
    Andrés JI; De Angelis M; Alcázar J; Celen S; Bormans G
    Curr Top Med Chem; 2012; 12(11):1224-36. PubMed ID: 22571785
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of Novel Indole-Based Allosteric Highly Potent ATX Inhibitors with Great
    Lei H; Guo M; Li X; Jia F; Li C; Yang Y; Cao M; Jiang N; Ma E; Zhai X
    J Med Chem; 2020 Jul; 63(13):7326-7346. PubMed ID: 32479084
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Preclinical evaluation of [(18)F]JNJ42259152 as a PET tracer for PDE10A.
    Celen S; Koole M; Ooms M; De Angelis M; Sannen I; Cornelis J; Alcazar J; Schmidt M; Verbruggen A; Langlois X; Van Laere K; Andrés JI; Bormans G
    Neuroimage; 2013 Nov; 82():13-22. PubMed ID: 23664955
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.