BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

125 related articles for article (PubMed ID: 34664502)

  • 1. Mechanism-Based Inactivation of
    Mellott DM; Torres D; Krieger IV; Cameron SA; Moghadamchargari Z; Laganowsky A; Sacchettini JC; Meek TD; Harris LD
    J Am Chem Soc; 2021 Oct; 143(42):17666-17676. PubMed ID: 34664502
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Covalent Inactivation of
    Pham TV; Mellott DM; Moghadamchargari Z; Chen K; Krieger I; Laganowsky A; Sacchettini JC; Meek TD
    ACS Chem Biol; 2021 Mar; 16(3):463-470. PubMed ID: 33688722
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mechanism-based inactivator of isocitrate lyases 1 and 2 from
    Pham TV; Murkin AS; Moynihan MM; Harris L; Tyler PC; Shetty N; Sacchettini JC; Huang HL; Meek TD
    Proc Natl Acad Sci U S A; 2017 Jul; 114(29):7617-7622. PubMed ID: 28679637
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Nitro Group as a Masked Electrophile in Covalent Enzyme Inhibition.
    Ray S; Kreitler DF; Gulick AM; Murkin AS
    ACS Chem Biol; 2018 Jun; 13(6):1470-1473. PubMed ID: 29782144
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cysteine is the general base that serves in catalysis by isocitrate lyase and in mechanism-based inhibition by 3-nitropropionate.
    Moynihan MM; Murkin AS
    Biochemistry; 2014 Jan; 53(1):178-87. PubMed ID: 24354272
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure of isocitrate lyase, a persistence factor of Mycobacterium tuberculosis.
    Sharma V; Sharma S; Hoener zu Bentrup K; McKinney JD; Russell DG; Jacobs WR; Sacchettini JC
    Nat Struct Biol; 2000 Aug; 7(8):663-8. PubMed ID: 10932251
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mycobacterium tuberculosis isocitrate lyases 1 and 2 are jointly required for in vivo growth and virulence.
    Muñoz-Elías EJ; McKinney JD
    Nat Med; 2005 Jun; 11(6):638-44. PubMed ID: 15895072
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Solvent isotope-induced equilibrium perturbation for isocitrate lyase.
    Quartararo CE; Hadi T; Cahill SM; Blanchard JS
    Biochemistry; 2013 Dec; 52(51):9286-93. PubMed ID: 24261638
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Heterogeneous multimeric structure of isocitrate lyase in complex with succinate and itaconate provides novel insights into its inhibitory mechanism.
    Kwon S; Chun HL; Ha HJ; Lee SY; Park HH
    PLoS One; 2021; 16(5):e0251067. PubMed ID: 33951112
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Advances in mycobacterial isocitrate lyase targeting and inhibitors.
    Krátký M; Vinšová J
    Curr Med Chem; 2012; 19(36):6126-37. PubMed ID: 23092127
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis of various 3-nitropropionamides as Mycobacterium tuberculosis isocitrate lyase inhibitor.
    Sriram D; Yogeeswari P; Methuku S; Vyas DR; Senthilkumar P; Alvala M; Jeankumar VU
    Bioorg Med Chem Lett; 2011 Sep; 21(18):5149-54. PubMed ID: 21840711
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dual role of isocitrate lyase 1 in the glyoxylate and methylcitrate cycles in Mycobacterium tuberculosis.
    Gould TA; van de Langemheen H; Muñoz-Elías EJ; McKinney JD; Sacchettini JC
    Mol Microbiol; 2006 Aug; 61(4):940-7. PubMed ID: 16879647
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of isocitrate lyase by 3-nitropropionate, a reaction-intermediate analogue.
    Schloss JV; Cleland WW
    Biochemistry; 1982 Aug; 21(18):4420-7. PubMed ID: 7126549
    [No Abstract]   [Full Text] [Related]  

  • 14. Structure-based screening and molecular dynamics simulations offer novel natural compounds as potential inhibitors of Mycobacterium tuberculosis isocitrate lyase.
    Shukla R; Shukla H; Sonkar A; Pandey T; Tripathi T
    J Biomol Struct Dyn; 2018 Jun; 36(8):2045-2057. PubMed ID: 28605994
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Regulation of the
    Ko EM; Kim JY; Lee S; Kim S; Hwang J; Oh JI
    J Bacteriol; 2021 Nov; 203(23):e0040221. PubMed ID: 34516281
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterization of activity and expression of isocitrate lyase in Mycobacterium avium and Mycobacterium tuberculosis.
    Höner Zu Bentrup K; Miczak A; Swenson DL; Russell DG
    J Bacteriol; 1999 Dec; 181(23):7161-7. PubMed ID: 10572116
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of a novel inhibitor of isocitrate lyase as a potent antitubercular agent against both active and non-replicating Mycobacterium tuberculosis.
    Liu Y; Zhou S; Deng Q; Li X; Meng J; Guan Y; Li C; Xiao C
    Tuberculosis (Edinb); 2016 Mar; 97():38-46. PubMed ID: 26980494
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Isocitrate lyase of Mycobacterium tuberculosis is inhibited by quercetin through binding at N-terminus.
    Shukla H; Kumar V; Singh AK; Rastogi S; Khan SR; Siddiqi MI; Krishnan MY; Akhtar MS
    Int J Biol Macromol; 2015; 78():137-41. PubMed ID: 25869309
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure-function insights into elusive Mycobacterium tuberculosis protein Rv1916.
    Antil M; Sharma J; Brissonnet Y; Choudhary M; Gouin S; Gupta V
    Int J Biol Macromol; 2019 Dec; 141():927-936. PubMed ID: 31505209
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Microbiology. A weak link in TB bacterium is found.
    Helmuth L
    Science; 2000 Aug; 289(5482):1123-5. PubMed ID: 10970221
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.