124 related articles for article (PubMed ID: 34664962)
21. Discovery of novel inhibitors of human phosphoglycerate dehydrogenase by activity-directed combinatorial chemical synthesis strategy.
Zhou X; Tan Y; Gou K; Tao L; Luo Y; Zhou Y; Zuo Z; Sun Q; Luo Y; Zhao Y
Bioorg Chem; 2021 Oct; 115():105159. PubMed ID: 34298241
[TBL] [Abstract][Full Text] [Related]
22. Phosphoglycerate dehydrogenase promotes pancreatic cancer development by interacting with eIF4A1 and eIF4E.
Ma X; Li B; Liu J; Fu Y; Luo Y
J Exp Clin Cancer Res; 2019 Feb; 38(1):66. PubMed ID: 30744688
[TBL] [Abstract][Full Text] [Related]
23. A retrospective overview of PHGDH and its inhibitors for regulating cancer metabolism.
Zhao JY; Feng KR; Wang F; Zhang JW; Cheng JF; Lin GQ; Gao D; Tian P
Eur J Med Chem; 2021 May; 217():113379. PubMed ID: 33756126
[TBL] [Abstract][Full Text] [Related]
24. Low glucose metabolite 3-phosphoglycerate switches PHGDH from serine synthesis to p53 activation to control cell fate.
Wu YQ; Zhang CS; Xiong J; Cai DQ; Wang CZ; Wang Y; Liu YH; Wang Y; Li Y; Wu J; Wu J; Lan B; Wang X; Chen S; Cao X; Wei X; Hu HH; Guo H; Yu Y; Ghafoor A; Xie C; Wu Y; Xu Z; Zhang C; Zhu M; Huang X; Sun X; Lin SY; Piao HL; Zhou J; Lin SC
Cell Res; 2023 Nov; 33(11):835-850. PubMed ID: 37726403
[TBL] [Abstract][Full Text] [Related]
25. The Role of D-3-Phosphoglycerate Dehydrogenase in Cancer.
Zhao X; Fu J; Du J; Xu W
Int J Biol Sci; 2020; 16(9):1495-1506. PubMed ID: 32226297
[TBL] [Abstract][Full Text] [Related]
26. Limited Environmental Serine and Glycine Confer Brain Metastasis Sensitivity to PHGDH Inhibition.
Ngo B; Kim E; Osorio-Vasquez V; Doll S; Bustraan S; Liang RJ; Luengo A; Davidson SM; Ali A; Ferraro GB; Fischer GM; Eskandari R; Kang DS; Ni J; Plasger A; Rajasekhar VK; Kastenhuber ER; Bacha S; Sriram RK; Stein BD; Bakhoum SF; Snuderl M; Cotzia P; Healey JH; Mainolfi N; Suri V; Friedman A; Manfredi M; Sabatini DM; Jones DR; Yu M; Zhao JJ; Jain RK; Keshari KR; Davies MA; Vander Heiden MG; Hernando E; Mann M; Cantley LC; Pacold ME
Cancer Discov; 2020 Sep; 10(9):1352-1373. PubMed ID: 32571778
[TBL] [Abstract][Full Text] [Related]
27. Human phosphoglycerate dehydrogenase produces the oncometabolite D-2-hydroxyglutarate.
Fan J; Teng X; Liu L; Mattaini KR; Looper RE; Vander Heiden MG; Rabinowitz JD
ACS Chem Biol; 2015 Feb; 10(2):510-6. PubMed ID: 25406093
[TBL] [Abstract][Full Text] [Related]
28. Homoharringtonine as a PHGDH inhibitor: Unraveling metabolic dependencies and developing a potent therapeutic strategy for high-risk neuroblastoma.
Hsieh CH; Huang CT; Cheng YS; Hsu CH; Hsu WM; Chung YH; Liu YL; Yang TS; Chien CY; Lee YH; Huang HC; Juan HF
Biomed Pharmacother; 2023 Oct; 166():115429. PubMed ID: 37673018
[TBL] [Abstract][Full Text] [Related]
29. Parkin ubiquitinates phosphoglycerate dehydrogenase to suppress serine synthesis and tumor progression.
Liu J; Zhang C; Wu H; Sun XX; Li Y; Huang S; Yue X; Lu SE; Shen Z; Su X; White E; Haffty BG; Hu W; Feng Z
J Clin Invest; 2020 Jun; 130(6):3253-3269. PubMed ID: 32478681
[TBL] [Abstract][Full Text] [Related]
30. Discovery of Novel Drug-like PHGDH Inhibitors to Disrupt Serine Biosynthesis for Cancer Therapy.
Gao D; Tang S; Cen Y; Yuan L; Lan X; Li QH; Lin GQ; Huang M; Tian P
J Med Chem; 2023 Jan; 66(1):285-305. PubMed ID: 36594670
[TBL] [Abstract][Full Text] [Related]
31. Metabolic shift to serine biosynthesis through 3-PG accumulation and PHGDH induction promotes tumor growth in pancreatic cancer.
Itoyama R; Yasuda-Yoshihara N; Kitamura F; Yasuda T; Bu L; Yonemura A; Uchihara T; Arima K; Hu X; Jun Z; Okamoto Y; Akiyama T; Yamashita K; Nakao Y; Yusa T; Kitano Y; Higashi T; Miyata T; Imai K; Hayashi H; Yamashita YI; Mikawa T; Kondoh H; Baba H; Ishimoto T
Cancer Lett; 2021 Dec; 523():29-42. PubMed ID: 34508795
[TBL] [Abstract][Full Text] [Related]
32. p53 Protein-mediated regulation of phosphoglycerate dehydrogenase (PHGDH) is crucial for the apoptotic response upon serine starvation.
Ou Y; Wang SJ; Jiang L; Zheng B; Gu W
J Biol Chem; 2015 Jan; 290(1):457-66. PubMed ID: 25404730
[TBL] [Abstract][Full Text] [Related]
33. EWS-FLI1-regulated Serine Synthesis and Exogenous Serine are Necessary for Ewing Sarcoma Cellular Proliferation and Tumor Growth.
Issaq SH; Mendoza A; Kidner R; Rosales TI; Duveau DY; Heske CM; Rohde JM; Boxer MB; Thomas CJ; DeBerardinis RJ; Helman LJ
Mol Cancer Ther; 2020 Jul; 19(7):1520-1529. PubMed ID: 32371575
[TBL] [Abstract][Full Text] [Related]
34. Prognostic significance of phosphoglycerate dehydrogenase in breast cancer.
Chandrika M; Chua PJ; Muniasamy U; Huang RYJ; Thike AA; Ng CT; Tan PH; Yip GW; Bay BH
Breast Cancer Res Treat; 2021 Apr; 186(3):655-665. PubMed ID: 33625616
[TBL] [Abstract][Full Text] [Related]
35. Phosphoglycerate dehydrogenase inhibition induces p-mTOR-independent autophagy and promotes multilineage differentiation in embryonal carcinoma stem-like cells.
Sharif T; Martell E; Dai C; Ghassemi-Rad MS; Lee K; Singh SK; Weaver ICG; Gujar S
Cell Death Dis; 2018 Sep; 9(10):990. PubMed ID: 30250195
[TBL] [Abstract][Full Text] [Related]
36. Phosphoglycerate dehydrogenase is dispensable for breast tumor maintenance and growth.
Chen J; Chung F; Yang G; Pu M; Gao H; Jiang W; Yin H; Capka V; Kasibhatla S; Laffitte B; Jaeger S; Pagliarini R; Chen Y; Zhou W
Oncotarget; 2013 Dec; 4(12):2502-11. PubMed ID: 24318446
[TBL] [Abstract][Full Text] [Related]
37. Acetylation Stabilizes Phosphoglycerate Dehydrogenase by Disrupting the Interaction of E3 Ligase RNF5 to Promote Breast Tumorigenesis.
Wang C; Wan X; Yu T; Huang Z; Shen C; Qi Q; Xiang S; Chen X; Arbely E; Ling ZQ; Liu CY; Yu W
Cell Rep; 2020 Aug; 32(6):108021. PubMed ID: 32783943
[TBL] [Abstract][Full Text] [Related]
38. Phosphoglycerate dehydrogenase positively regulates the proliferation of chicken muscle cells.
Wang H; Hu M; Ding Z; Zhou X; Yang S; Shen Z; Yan F; Zhao A
Poult Sci; 2022 May; 101(5):101805. PubMed ID: 35344765
[TBL] [Abstract][Full Text] [Related]
39. Biophysical and biochemical properties of PHGDH revealed by studies on PHGDH inhibitors.
Tan Y; Zhou X; Gong Y; Gou K; Luo Y; Jia D; Dai L; Zhao Y; Sun Q
Cell Mol Life Sci; 2021 Dec; 79(1):27. PubMed ID: 34971423
[TBL] [Abstract][Full Text] [Related]
40. Serine Synthesis via PHGDH Is Essential for Heme Production in Endothelial Cells.
Vandekeere S; Dubois C; Kalucka J; Sullivan MR; García-Caballero M; Goveia J; Chen R; Diehl FF; Bar-Lev L; Souffreau J; Pircher A; Kumar S; Vinckier S; Hirabayashi Y; Furuya S; Schoonjans L; Eelen G; Ghesquière B; Keshet E; Li X; Vander Heiden MG; Dewerchin M; Carmeliet P
Cell Metab; 2018 Oct; 28(4):573-587.e13. PubMed ID: 30017355
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]