These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
334 related articles for article (PubMed ID: 34674843)
1. It's time to deconstruct treatment-failure: A randomized controlled trial of nonoperative management of uncomplicated pediatric appendicitis with antibiotics alone. Perez Otero S; Metzger JW; Choi BH; Ramaraj A; Tashiro J; Kuenzler KA; Ginsburg HB; Tomita SS; Fisher JC J Pediatr Surg; 2022 Jan; 57(1):56-62. PubMed ID: 34674843 [TBL] [Abstract][Full Text] [Related]
2. Association of Nonoperative Management Using Antibiotic Therapy vs Laparoscopic Appendectomy With Treatment Success and Disability Days in Children With Uncomplicated Appendicitis. Minneci PC; Hade EM; Lawrence AE; Sebastião YV; Saito JM; Mak GZ; Fox C; Hirschl RB; Gadepalli S; Helmrath MA; Kohler JE; Leys CM; Sato TT; Lal DR; Landman MP; Kabre R; Fallat ME; Cooper JN; Deans KJ; JAMA; 2020 Aug; 324(6):581-593. PubMed ID: 32730561 [TBL] [Abstract][Full Text] [Related]
3. Effectiveness of Patient Choice in Nonoperative vs Surgical Management of Pediatric Uncomplicated Acute Appendicitis. Minneci PC; Mahida JB; Lodwick DL; Sulkowski JP; Nacion KM; Cooper JN; Ambeba EJ; Moss RL; Deans KJ JAMA Surg; 2016 May; 151(5):408-15. PubMed ID: 26676711 [TBL] [Abstract][Full Text] [Related]
4. Comparison of Antibiotic Therapy and Appendectomy for Acute Uncomplicated Appendicitis in Children: A Meta-analysis. Huang L; Yin Y; Yang L; Wang C; Li Y; Zhou Z JAMA Pediatr; 2017 May; 171(5):426-434. PubMed ID: 28346589 [TBL] [Abstract][Full Text] [Related]
5. Antibiotic Therapy vs Appendectomy for Treatment of Uncomplicated Acute Appendicitis: The APPAC Randomized Clinical Trial. Salminen P; Paajanen H; Rautio T; Nordström P; Aarnio M; Rantanen T; Tuominen R; Hurme S; Virtanen J; Mecklin JP; Sand J; Jartti A; Rinta-Kiikka I; Grönroos JM JAMA; 2015 Jun; 313(23):2340-8. PubMed ID: 26080338 [TBL] [Abstract][Full Text] [Related]
6. Five-Year Follow-up of Antibiotic Therapy for Uncomplicated Acute Appendicitis in the APPAC Randomized Clinical Trial. Salminen P; Tuominen R; Paajanen H; Rautio T; Nordström P; Aarnio M; Rantanen T; Hurme S; Mecklin JP; Sand J; Virtanen J; Jartti A; Grönroos JM JAMA; 2018 Sep; 320(12):1259-1265. PubMed ID: 30264120 [TBL] [Abstract][Full Text] [Related]
7. Effect of Oral Moxifloxacin vs Intravenous Ertapenem Plus Oral Levofloxacin for Treatment of Uncomplicated Acute Appendicitis: The APPAC II Randomized Clinical Trial. Sippola S; Haijanen J; Grönroos J; Rautio T; Nordström P; Rantanen T; Pinta T; Ilves I; Mattila A; Rintala J; Löyttyniemi E; Hurme S; Tammilehto V; Marttila H; Meriläinen S; Laukkarinen J; Sävelä EL; Savolainen H; Sippola T; Aarnio M; Paajanen H; Salminen P JAMA; 2021 Jan; 325(4):353-362. PubMed ID: 33427870 [TBL] [Abstract][Full Text] [Related]
8. Nonoperative treatment with antibiotics versus surgery for acute nonperforated appendicitis in children: a pilot randomized controlled trial. Svensson JF; Patkova B; Almström M; Naji H; Hall NJ; Eaton S; Pierro A; Wester T Ann Surg; 2015 Jan; 261(1):67-71. PubMed ID: 25072441 [TBL] [Abstract][Full Text] [Related]
9. Nonoperative vs Operative Management of Uncomplicated Acute Appendicitis: A Systematic Review and Meta-analysis. de Almeida Leite RM; Seo DJ; Gomez-Eslava B; Hossain S; Lesegretain A; de Souza AV; Bay CP; Zilberstein B; Marchi E; Machado RB; Barchi LC; Ricciardi R JAMA Surg; 2022 Sep; 157(9):828-834. PubMed ID: 35895073 [TBL] [Abstract][Full Text] [Related]
10. Antibiotic Treatment and Appendectomy for Uncomplicated Acute Appendicitis in Adults and Children: A Systematic Review and Meta-analysis. Podda M; Gerardi C; Cillara N; Fearnhead N; Gomes CA; Birindelli A; Mulliri A; Davies RJ; Di Saverio S Ann Surg; 2019 Dec; 270(6):1028-1040. PubMed ID: 30720508 [TBL] [Abstract][Full Text] [Related]
11. Antibiotics-First Versus Surgery for Appendicitis: A US Pilot Randomized Controlled Trial Allowing Outpatient Antibiotic Management. Talan DA; Saltzman DJ; Mower WR; Krishnadasan A; Jude CM; Amii R; DeUgarte DA; Wu JX; Pathmarajah K; Morim A; Moran GJ; Ann Emerg Med; 2017 Jul; 70(1):1-11.e9. PubMed ID: 27974169 [TBL] [Abstract][Full Text] [Related]
12. Three-Year Outcomes of Oral Antibiotics vs Intravenous and Oral Antibiotics for Uncomplicated Acute Appendicitis: A Secondary Analysis of the APPAC II Randomized Clinical Trial. Selänne L; Haijanen J; Sippola S; Hurme S; Rautio T; Nordström P; Rantanen T; Pinta T; Ilves I; Mattila A; Rintala J; Marttila H; Meriläinen S; Laukkarinen J; Sävelä EL; Paajanen H; Grönroos J; Salminen P JAMA Surg; 2024 Jul; 159(7):727-735. PubMed ID: 38630471 [TBL] [Abstract][Full Text] [Related]
13. Antibiotics-first strategy for uncomplicated acute appendicitis in adults is associated with increased rates of peritonitis at surgery. A systematic review with meta-analysis of randomized controlled trials comparing appendectomy and non-operative management with antibiotics. Podda M; Cillara N; Di Saverio S; Lai A; Feroci F; Luridiana G; Agresta F; Vettoretto N; Surgeon; 2017 Oct; 15(5):303-314. PubMed ID: 28284517 [TBL] [Abstract][Full Text] [Related]
14. Quality of Life and Patient Satisfaction at 7-Year Follow-up of Antibiotic Therapy vs Appendectomy for Uncomplicated Acute Appendicitis: A Secondary Analysis of a Randomized Clinical Trial. Sippola S; Haijanen J; Viinikainen L; Grönroos J; Paajanen H; Rautio T; Nordström P; Aarnio M; Rantanen T; Hurme S; Mecklin JP; Sand J; Jartti A; Salminen P JAMA Surg; 2020 Apr; 155(4):283-289. PubMed ID: 32074268 [TBL] [Abstract][Full Text] [Related]
15. Systematic review of nonoperative versus operative treatment of uncomplicated appendicitis. Gorter RR; The SML; Gorter-Stam MAW; Eker HH; Bakx R; van der Lee JH; Heij HA J Pediatr Surg; 2017 Aug; 52(8):1219-1227. PubMed ID: 28449821 [TBL] [Abstract][Full Text] [Related]
16. Cost analysis of antibiotic therapy versus appendectomy for treatment of uncomplicated acute appendicitis: 5-year results of the APPAC randomized clinical trial. Haijanen J; Sippola S; Tuominen R; Grönroos J; Paajanen H; Rautio T; Nordström P; Aarnio M; Rantanen T; Hurme S; Salminen P PLoS One; 2019; 14(7):e0220202. PubMed ID: 31344073 [TBL] [Abstract][Full Text] [Related]
17. Never put equipoise in appendix! Final results of ASAA (antibiotics vs. surgery for uncomplicated acute appendicitis in adults) randomized controlled trial. Ceresoli M; Pisano M; Allievi N; Poiasina E; Coccolini F; Montori G; Fugazzola P; Ansaloni L Updates Surg; 2019 Jun; 71(2):381-387. PubMed ID: 30560527 [TBL] [Abstract][Full Text] [Related]
18. A randomized, controlled multicenter feasibility pilot trial on imaging confirmed uncomplicated acute appendicitis: Appendectomy vs. symptomatic treatment in pediatric patients (the APPSYPP) trial study protocol. Puputti J; Suominen JS; Luoto T; Hiltunen P; Ripatti L; Nikoskelainen M; Nuutinen S; Sinikumpu JJ; Tahkola E; Porela-Tiihonen S; Hurme S; Salminen P; Pakarinen MP Contemp Clin Trials; 2022 Dec; 123():106970. PubMed ID: 36280033 [TBL] [Abstract][Full Text] [Related]
19. Feasibility of a nonoperative management strategy for uncomplicated acute appendicitis in children. Minneci PC; Sulkowski JP; Nacion KM; Mahida JB; Cooper JN; Moss RL; Deans KJ J Am Coll Surg; 2014 Aug; 219(2):272-9. PubMed ID: 24951281 [TBL] [Abstract][Full Text] [Related]