BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

232 related articles for article (PubMed ID: 34678705)

  • 21. Elucidation of the metabolites of the novel psychoactive substance 4-methyl-N-ethyl-cathinone (4-MEC) in human urine and pooled liver microsomes by GC-MS and LC-HR-MS/MS techniques and of its detectability by GC-MS or LC-MS(n) standard screening approaches.
    Helfer AG; Turcant A; Boels D; Ferec S; Lelièvre B; Welter J; Meyer MR; Maurer HH
    Drug Test Anal; 2015 May; 7(5):368-75. PubMed ID: 24953431
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Acebutolol and alprenolol metabolism predictions: comparative study of electrochemical and cytochrome P450-catalyzed reactions using liquid chromatography coupled to high-resolution mass spectrometry.
    Bussy U; Delaforge M; El-Bekkali C; Ferchaud-Roucher V; Krempf M; Tea I; Galland N; Jacquemin D; Boujtita M
    Anal Bioanal Chem; 2013 Jul; 405(18):6077-85. PubMed ID: 23700103
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Quantitative determination and metabolic profiling of synthetic cathinone eutylone in vitro and in urine samples by liquid chromatography tandem quadrupole time-of-flight mass spectrometry.
    Yeh YL; Wang SM
    Drug Test Anal; 2022 Jul; 14(7):1325-1337. PubMed ID: 35332690
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Phase I metabolic profiling of the synthetic cannabinoids THJ-018 and THJ-2201 in human urine in comparison to human liver microsome and cytochrome P450 isoenzyme incubation.
    Gaunitz F; Thomas A; Fietzke M; Franz F; Auwärter V; Thevis M; Mercer-Chalmers-Bender K
    Int J Legal Med; 2019 Jul; 133(4):1049-1064. PubMed ID: 30564916
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Phenethylamine-derived new psychoactive substances 2C-E-FLY, 2C-EF-FLY, and 2C-T-7-FLY: Investigations on their metabolic fate including isoenzyme activities and their toxicological detectability in urine screenings.
    Wagmann L; Hempel N; Richter LHJ; Brandt SD; Stratford A; Meyer MR
    Drug Test Anal; 2019 Oct; 11(10):1507-1521. PubMed ID: 31299701
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Identification of in vitro and in vivo human metabolites of the new psychoactive substance nitracaine by liquid chromatography coupled to quadrupole time-of-flight mass spectrometry.
    Negreira N; Kinyua J; De Brabanter N; Maudens K; van Nuijs AL
    Anal Bioanal Chem; 2016 Jul; 408(19):5221-9. PubMed ID: 27185541
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Two-injection workflow for a liquid chromatography/LTQ-Orbitrap system to complete in vivo biotransformation characterization: demonstration with buspirone metabolite identification.
    Li AC; Ding J; Jiang X; Denissen J
    Rapid Commun Mass Spectrom; 2009 Sep; 23(18):3003-12. PubMed ID: 19681099
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Suspect and non-target screening workflows to investigate the in vitro and in vivo metabolism of the synthetic cannabinoid 5Cl-THJ-018.
    Vervliet P; Mortelé O; Gys C; Degreef M; Lanckmans K; Maudens K; Covaci A; van Nuijs ALN; Lai FY
    Drug Test Anal; 2019 Mar; 11(3):479-491. PubMed ID: 30242979
    [TBL] [Abstract][Full Text] [Related]  

  • 29. A further insight into the metabolic profile of the nuclear receptor Rev-erb agonist, SR9009.
    Mazzarino M; Rizzato N; Stacchini C; de la Torre X; Botrè F
    Drug Test Anal; 2018 Nov; 10(11-12):1670-1681. PubMed ID: 30395700
    [TBL] [Abstract][Full Text] [Related]  

  • 30. New Psychoactive Substances 3-Methoxyphencyclidine (3-MeO-PCP) and 3-Methoxyrolicyclidine (3-MeO-PCPy): Metabolic Fate Elucidated with Rat Urine and Human Liver Preparations and their Detectability in Urine by GC-MS, "LC-(High Resolution)-MSn" and "LC-(High Resolution)-MS/MS".
    A Michely JA; Manier SK; Caspar AT; Brandt SD; Wallach J; Maurer HH
    Curr Neuropharmacol; 2017; 15(5):692-712. PubMed ID: 27758707
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Liquid chromatography-quadrupole time-of-flight mass spectrometry for screening in vitro drug metabolites in humans: investigation on seven phenethylamine-based designer drugs.
    Lai FY; Erratico C; Kinyua J; Mueller JF; Covaci A; van Nuijs AL
    J Pharm Biomed Anal; 2015 Oct; 114():355-75. PubMed ID: 26112925
    [TBL] [Abstract][Full Text] [Related]  

  • 32. First metabolic profile of PV8, a novel synthetic cathinone, in human hepatocytes and urine by high-resolution mass spectrometry.
    Swortwood MJ; Ellefsen KN; Wohlfarth A; Diao X; Concheiro-Guisan M; Kronstrand R; Huestis MA
    Anal Bioanal Chem; 2016 Jul; 408(18):4845-56. PubMed ID: 27185540
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Toxicokinetics of new psychoactive substances: plasma protein binding, metabolic stability, and human phase I metabolism of the synthetic cannabinoid WIN 55,212-2 studied using in vitro tools and LC-HR-MS/MS.
    Mardal M; Gracia-Lor E; Leibnitz S; Castiglioni S; Meyer MR
    Drug Test Anal; 2016 Oct; 8(10):1039-1048. PubMed ID: 26810883
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Characterization and in vitro phase I microsomal metabolism of designer benzodiazepines: An update comprising flunitrazolam, norflurazepam, and 4'-chlorodiazepam (Ro5-4864).
    Moosmann B; Bisel P; Westphal F; Wilde M; Kempf J; Angerer V; Auwärter V
    Drug Test Anal; 2019 Mar; 11(3):541-549. PubMed ID: 30578721
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Lefetamine-derived designer drugs N-ethyl-1,2-diphenylethylamine (NEDPA) and N-iso-propyl-1,2-diphenylethylamine (NPDPA): metabolism and detectability in rat urine using GC-MS, LC-MSn and LC-HR-MS/MS.
    Wink CS; Meyer GM; Wissenbach DK; Jacobsen-Bauer A; Meyer MR; Maurer HH
    Drug Test Anal; 2014 Oct; 6(10):1038-48. PubMed ID: 24591097
    [TBL] [Abstract][Full Text] [Related]  

  • 36. In vitro metabolism of BIIB021, an inhibitor of heat shock protein 90, in liver microsomes and hepatocytes of rats, dogs, and humans and recombinant human cytochrome P450 isoforms.
    Xu L; Woodward C; Khan S; Prakash C
    Drug Metab Dispos; 2012 Apr; 40(4):680-93. PubMed ID: 22217465
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Identification of phase I and II metabolites of the new designer drug α-pyrrolidinohexiophenone (α-PHP) in human urine by liquid chromatography quadrupole time-of-flight mass spectrometry (LC-QTOF-MS).
    Paul M; Bleicher S; Guber S; Ippisch J; Polettini A; Schultis W
    J Mass Spectrom; 2015 Nov; 50(11):1305-17. PubMed ID: 26505776
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Untargeted metabolomics by high resolution mass spectrometry coupled to normal and reversed phase liquid chromatography as a tool to study the in vitro biotransformation of new psychoactive substances.
    Manier SK; Keller A; Schäper J; Meyer MR
    Sci Rep; 2019 Feb; 9(1):2741. PubMed ID: 30808896
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Comparative metabolism of four limonoids in human liver microsomes using ultra-high-performance liquid chromatography coupled with high-resolution LTQ-Orbitrap mass spectrometry.
    Ren W; Xin SK; Han LY; Zuo R; Li Y; Gong MX; Wei XL; Zhou YY; He J; Wang HJ; Si N; Zhao HY; Yang J; Bian BL
    Rapid Commun Mass Spectrom; 2015 Nov; 29(21):2045-56. PubMed ID: 26443405
    [TBL] [Abstract][Full Text] [Related]  

  • 40. High-resolution mass spectrometric metabolite profiling of a novel synthetic designer drug, N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indole-3-carboxamide (STS-135), using cryopreserved human hepatocytes and assessment of metabolic stability with human liver microsomes.
    Gandhi AS; Wohlfarth A; Zhu M; Pang S; Castaneto M; Scheidweiler KB; Huestis MA
    Drug Test Anal; 2015 Mar; 7(3):187-98. PubMed ID: 24827428
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.