BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

580 related articles for article (PubMed ID: 34685754)

  • 1. Coactivation of GSK3β and IGF-1 Attenuates Amyotrophic Lateral Sclerosis Nerve Fiber Cytopathies in SOD1 Mutant Patient-Derived Motor Neurons.
    Ting HC; Yang HI; Harn HJ; Chiu IM; Su HL; Li X; Chen MF; Ho TJ; Liu CA; Tsai YJ; Chiou TW; Lin SZ; Chang CY
    Cells; 2021 Oct; 10(10):. PubMed ID: 34685754
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Induced pluripotent stem cell-derived motor neurons from amyotrophic lateral sclerosis (ALS) patients carrying different superoxide dismutase 1 mutations recapitulate pathological features of ALS.
    Liu WC; Liu N; Wang Y; Huang C; Li YF; Wang H; Li XG; Deng M
    Chin Med J (Engl); 2021 Oct; 134(20):2457-2464. PubMed ID: 34669638
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Altered calcium dynamics and glutamate receptor properties in iPSC-derived motor neurons from ALS patients with C9orf72, FUS, SOD1 or TDP43 mutations.
    Bursch F; Kalmbach N; Naujock M; Staege S; Eggenschwiler R; Abo-Rady M; Japtok J; Guo W; Hensel N; Reinhardt P; Boeckers TM; Cantz T; Sterneckert J; Van Den Bosch L; Hermann A; Petri S; Wegner F
    Hum Mol Genet; 2019 Sep; 28(17):2835-2850. PubMed ID: 31108504
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Interfering with lysophosphatidic acid receptor edg2/lpa
    Gento-Caro Á; Vilches-Herrando E; García-Morales V; Portillo F; Rodríguez-Bey G; González-Forero D; Moreno-López B
    Neuropathol Appl Neurobiol; 2021 Dec; 47(7):1004-1018. PubMed ID: 33508894
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mir-17∼92 Confers Motor Neuron Subtype Differential Resistance to ALS-Associated Degeneration.
    Tung YT; Peng KC; Chen YC; Yen YP; Chang M; Thams S; Chen JA
    Cell Stem Cell; 2019 Aug; 25(2):193-209.e7. PubMed ID: 31155482
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Knocking down metabotropic glutamate receptor 1 improves survival and disease progression in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis.
    Milanese M; Giribaldi F; Melone M; Bonifacino T; Musante I; Carminati E; Rossi PI; Vergani L; Voci A; Conti F; Puliti A; Bonanno G
    Neurobiol Dis; 2014 Apr; 64():48-59. PubMed ID: 24361555
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Genetic Correction of SOD1 Mutant iPSCs Reveals ERK and JNK Activated AP1 as a Driver of Neurodegeneration in Amyotrophic Lateral Sclerosis.
    Bhinge A; Namboori SC; Zhang X; VanDongen AMJ; Stanton LW
    Stem Cell Reports; 2017 Apr; 8(4):856-869. PubMed ID: 28366453
    [TBL] [Abstract][Full Text] [Related]  

  • 8. In-vivo effects of knocking-down metabotropic glutamate receptor 5 in the SOD1
    Bonifacino T; Cattaneo L; Gallia E; Puliti A; Melone M; Provenzano F; Bossi S; Musante I; Usai C; Conti F; Bonanno G; Milanese M
    Neuropharmacology; 2017 Sep; 123():433-445. PubMed ID: 28645622
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Modulation of the IGF1R-MTOR pathway attenuates motor neuron toxicity of human ALS SOD1
    Granatiero V; Sayles NM; Savino AM; Konrad C; Kharas MG; Kawamata H; Manfredi G
    Autophagy; 2021 Dec; 17(12):4029-4042. PubMed ID: 33749521
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mechanistic Insights of Astrocyte-Mediated Hyperactive Autophagy and Loss of Motor Neuron Function in SOD1
    Rajpurohit CS; Kumar V; Cheffer A; Oliveira D; Ulrich H; Okamoto OK; Zatz M; Ansari UA; Khanna VK; Pant AB
    Mol Neurobiol; 2020 Oct; 57(10):4117-4133. PubMed ID: 32676988
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeting low levels of MIF expression as a potential therapeutic strategy for ALS.
    Alfahel L; Gschwendtberger T; Kozareva V; Dumas L; Gibbs R; Kertser A; Baruch K; Zaccai S; Kahn J; Thau-Habermann N; Eggenschwiler R; Sterneckert J; Hermann A; Sundararaman N; Vaibhav V; Van Eyk JE; Rafuse VF; Fraenkel E; Cantz T; Petri S; Israelson A
    Cell Rep Med; 2024 May; 5(5):101546. PubMed ID: 38703766
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pathological Modification of TDP-43 in Amyotrophic Lateral Sclerosis with SOD1 Mutations.
    Jeon GS; Shim YM; Lee DY; Kim JS; Kang M; Ahn SH; Shin JY; Geum D; Hong YH; Sung JJ
    Mol Neurobiol; 2019 Mar; 56(3):2007-2021. PubMed ID: 29982983
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeting autotaxin impacts disease advance in the SOD1-G93A mouse model of amyotrophic lateral sclerosis.
    Gento-Caro Á; Vilches-Herrando E; Portillo F; González-Forero D; Moreno-López B
    Brain Pathol; 2022 May; 32(3):e13022. PubMed ID: 34585475
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Early deficits in GABA inhibition parallels an increase in L-type Ca
    Venugopal S; Ghulam-Jhelani Z; Ahn IS; Yang X; Wiedau M; Simmons D; Chandler SH
    Neurobiol Dis; 2023 Feb; 177():105992. PubMed ID: 36623607
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Modeling ALS with iPSCs reveals that mutant SOD1 misregulates neurofilament balance in motor neurons.
    Chen H; Qian K; Du Z; Cao J; Petersen A; Liu H; Blackbourn LW; Huang CL; Errigo A; Yin Y; Lu J; Ayala M; Zhang SC
    Cell Stem Cell; 2014 Jun; 14(6):796-809. PubMed ID: 24704493
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Alteration of Mitochondrial Integrity as Upstream Event in the Pathophysiology of SOD1-ALS.
    Günther R; Pal A; Williams C; Zimyanin VL; Liehr M; von Neubeck C; Krause M; Parab MG; Petri S; Kalmbach N; Marklund SL; Sterneckert J; Munch Andersen P; Wegner F; Gilthorpe JD; Hermann A
    Cells; 2022 Apr; 11(7):. PubMed ID: 35406813
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Vascular endothelial growth factor prevents G93A-SOD1-induced motor neuron degeneration.
    Lunn JS; Sakowski SA; Kim B; Rosenberg AA; Feldman EL
    Dev Neurobiol; 2009 Nov; 69(13):871-84. PubMed ID: 19672955
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Transgenic mice with human mutant genes causing Parkinson's disease and amyotrophic lateral sclerosis provide common insight into mechanisms of motor neuron selective vulnerability to degeneration.
    Martin LJ
    Rev Neurosci; 2007; 18(2):115-36. PubMed ID: 17593875
    [TBL] [Abstract][Full Text] [Related]  

  • 19. MAP4K4 Activation Mediates Motor Neuron Degeneration in Amyotrophic Lateral Sclerosis.
    Wu C; Watts ME; Rubin LL
    Cell Rep; 2019 Jan; 26(5):1143-1156.e5. PubMed ID: 30699345
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Autologous treatment for ALS with implication for broad neuroprotection.
    Kim D; Kim S; Sung A; Patel N; Wong N; Conboy MJ; Conboy IM
    Transl Neurodegener; 2022 Mar; 11(1):16. PubMed ID: 35272709
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 29.