BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

224 related articles for article (PubMed ID: 34686351)

  • 21. Defective regulation of autophagy upon leucine deprivation reveals a targetable liability of human melanoma cells in vitro and in vivo.
    Sheen JH; Zoncu R; Kim D; Sabatini DM
    Cancer Cell; 2011 May; 19(5):613-28. PubMed ID: 21575862
    [TBL] [Abstract][Full Text] [Related]  

  • 22. TRPing the homeostatic alarm - Melanoma cells are selectively vulnerable to TRPML1 deletion.
    Jung J; Venkatachalam K
    Cell Calcium; 2019 Dec; 84():102082. PubMed ID: 31634759
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Casticin Induced Apoptosis in A375.S2 Human Melanoma Cells through the Inhibition of NF-[Formula: see text]B and Mitochondria-Dependent Pathways In Vitro and Inhibited Human Melanoma Xenografts in a Mouse Model In Vivo.
    Shiue YW; Lu CC; Hsiao YP; Liao CL; Lin JP; Lai KC; Yu CC; Huang YP; Ho HC; Chung JG
    Am J Chin Med; 2016; 44(3):637-61. PubMed ID: 27109154
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Increases in Intracellular Zinc Enhance Proliferative Signaling as well as Mitochondrial and Endolysosomal Activity in Human Melanocytes.
    Rudolf E; Rudolf K
    Cell Physiol Biochem; 2017; 43(1):1-16. PubMed ID: 28848213
    [TBL] [Abstract][Full Text] [Related]  

  • 25. TRPML1: an ion channel in the lysosome.
    Wang W; Zhang X; Gao Q; Xu H
    Handb Exp Pharmacol; 2014; 222():631-45. PubMed ID: 24756723
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Novel small molecule XPO1/CRM1 inhibitors induce nuclear accumulation of TP53, phosphorylated MAPK and apoptosis in human melanoma cells.
    Yang J; Bill MA; Young GS; La Perle K; Landesman Y; Shacham S; Kauffman M; Senapedis W; Kashyap T; Saint-Martin JR; Kendra K; Lesinski GB
    PLoS One; 2014; 9(7):e102983. PubMed ID: 25057921
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Exploiting Honokiol-induced ER stress CHOP activation inhibits the growth and metastasis of melanoma by suppressing the MITF and β-catenin pathways.
    Chiu CS; Tsai CH; Hsieh MS; Tsai SC; Jan YJ; Lin WY; Lai DW; Wu SM; Hsing HY; Arbiser JL; Sheu ML
    Cancer Lett; 2019 Feb; 442():113-125. PubMed ID: 30391358
    [TBL] [Abstract][Full Text] [Related]  

  • 28. The activation of Mucolipin TRP channel 1 (TRPML1) protects motor neurons from L-BMAA neurotoxicity by promoting autophagic clearance.
    Tedeschi V; Petrozziello T; Sisalli MJ; Boscia F; Canzoniero LMT; Secondo A
    Sci Rep; 2019 Jul; 9(1):10743. PubMed ID: 31341250
    [TBL] [Abstract][Full Text] [Related]  

  • 29. BEL β-Trefoil Reduces the Migration Ability of RUNX2 Expressing Melanoma Cells in Xenotransplanted Zebrafish.
    Valenti MT; Marchetto G; Perduca M; Tiso N; Mottes M; Dalle Carbonare L
    Molecules; 2020 Mar; 25(6):. PubMed ID: 32168858
    [TBL] [Abstract][Full Text] [Related]  

  • 30. The role of BPTF in melanoma progression and in response to BRAF-targeted therapy.
    Dar AA; Nosrati M; Bezrookove V; de Semir D; Majid S; Thummala S; Sun V; Tong S; Leong SP; Minor D; Billings PR; Soroceanu L; Debs R; Miller JR; Sagebiel RW; Kashani-Sabet M
    J Natl Cancer Inst; 2015 Feb; 107(5):. PubMed ID: 25713167
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Up-regulation of lysosomal TRPML1 channels is essential for lysosomal adaptation to nutrient starvation.
    Wang W; Gao Q; Yang M; Zhang X; Yu L; Lawas M; Li X; Bryant-Genevier M; Southall NT; Marugan J; Ferrer M; Xu H
    Proc Natl Acad Sci U S A; 2015 Mar; 112(11):E1373-81. PubMed ID: 25733853
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Mutational activation of BRAF confers sensitivity to transforming growth factor beta inhibitors in human cancer cells.
    Spender LC; Ferguson GJ; Liu S; Cui C; Girotti MR; Sibbet G; Higgs EB; Shuttleworth MK; Hamilton T; Lorigan P; Weller M; Vincent DF; Sansom OJ; Frame M; Dijke PT; Marais R; Inman GJ
    Oncotarget; 2016 Dec; 7(50):81995-82012. PubMed ID: 27835901
    [TBL] [Abstract][Full Text] [Related]  

  • 33. LAMTOR1 inhibition of TRPML1-dependent lysosomal calcium release regulates dendritic lysosome trafficking and hippocampal neuronal function.
    Sun J; Liu Y; Hao X; Lin W; Su W; Chiang E; Baudry M; Bi X
    EMBO J; 2022 Mar; 41(5):e108119. PubMed ID: 35099830
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Gene expression analyses of primary melanomas reveal CTHRC1 as an important player in melanoma progression.
    Eriksson J; Le Joncour V; Nummela P; Jahkola T; Virolainen S; Laakkonen P; Saksela O; Hölttä E
    Oncotarget; 2016 Mar; 7(12):15065-92. PubMed ID: 26918341
    [TBL] [Abstract][Full Text] [Related]  

  • 35. BET inhibitor suppresses melanoma progression
    Deng G; Zeng F; Su J; Zhao S; Hu R; Zhu W; Hu S; Chen X; Yin M
    Theranostics; 2020; 10(25):11428-11443. PubMed ID: 33052224
    [No Abstract]   [Full Text] [Related]  

  • 36. The redox antimalarial dihydroartemisinin targets human metastatic melanoma cells but not primary melanocytes with induction of NOXA-dependent apoptosis.
    Cabello CM; Lamore SD; Bair WB; Qiao S; Azimian S; Lesson JL; Wondrak GT
    Invest New Drugs; 2012 Aug; 30(4):1289-301. PubMed ID: 21547369
    [TBL] [Abstract][Full Text] [Related]  

  • 37. miR-216b enhances the efficacy of vemurafenib by targeting Beclin-1, UVRAG and ATG5 in melanoma.
    Luo M; Wu L; Zhang K; Wang H; Wu S; O'Connell D; Gao T; Zhong H; Yang Y
    Cell Signal; 2018 Jan; 42():30-43. PubMed ID: 28982601
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Chaetocin induces apoptosis in human melanoma cells through the generation of reactive oxygen species and the intrinsic mitochondrial pathway, and exerts its anti-tumor activity in vivo.
    Han X; Han Y; Zheng Y; Sun Q; Ma T; Zhang J; Xu L
    PLoS One; 2017; 12(4):e0175950. PubMed ID: 28419143
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Zinc-dependent lysosomal enlargement in TRPML1-deficient cells involves MTF-1 transcription factor and ZnT4 (Slc30a4) transporter.
    Kukic I; Lee JK; Coblentz J; Kelleher SL; Kiselyov K
    Biochem J; 2013 Apr; 451(2):155-63. PubMed ID: 23368743
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Design and synthesis of pyrrolobenzodiazepine-gallic hybrid agents as p53-dependent and -independent apoptogenic signaling in melanoma cells.
    Chou YW; Senadi GC; Chen CY; Kuo KK; Lin YT; Wang JJ; Lee JH; Wang YC; Hu WP
    Eur J Med Chem; 2016 Feb; 109():59-74. PubMed ID: 26756315
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.