BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

346 related articles for article (PubMed ID: 34706264)

  • 1. ORF3a of SARS-CoV-2 promotes lysosomal exocytosis-mediated viral egress.
    Chen D; Zheng Q; Sun L; Ji M; Li Y; Deng H; Zhang H
    Dev Cell; 2021 Dec; 56(23):3250-3263.e5. PubMed ID: 34706264
    [TBL] [Abstract][Full Text] [Related]  

  • 2. ORF3a of the COVID-19 virus SARS-CoV-2 blocks HOPS complex-mediated assembly of the SNARE complex required for autolysosome formation.
    Miao G; Zhao H; Li Y; Ji M; Chen Y; Shi Y; Bi Y; Wang P; Zhang H
    Dev Cell; 2021 Feb; 56(4):427-442.e5. PubMed ID: 33422265
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Regulation of autophagy by SARS-CoV-2: The multifunctional contributions of ORF3a.
    Shariq M; Malik AA; Sheikh JA; Hasnain SE; Ehtesham NZ
    J Med Virol; 2023 Jul; 95(7):e28959. PubMed ID: 37485696
    [TBL] [Abstract][Full Text] [Related]  

  • 4. SARS-CoV-2 virulence factor ORF3a blocks lysosome function by modulating TBC1D5-dependent Rab7 GTPase cycle.
    Walia K; Sharma A; Paul S; Chouhan P; Kumar G; Ringe R; Sharma M; Tuli A
    Nat Commun; 2024 Mar; 15(1):2053. PubMed ID: 38448435
    [TBL] [Abstract][Full Text] [Related]  

  • 5. SARS-CoV-2 ORF3a Induces Incomplete Autophagy via the Unfolded Protein Response.
    Su WQ; Yu XJ; Zhou CM
    Viruses; 2021 Dec; 13(12):. PubMed ID: 34960736
    [TBL] [Abstract][Full Text] [Related]  

  • 6. β-Coronaviruses Use Lysosomes for Egress Instead of the Biosynthetic Secretory Pathway.
    Ghosh S; Dellibovi-Ragheb TA; Kerviel A; Pak E; Qiu Q; Fisher M; Takvorian PM; Bleck C; Hsu VW; Fehr AR; Perlman S; Achar SR; Straus MR; Whittaker GR; de Haan CAM; Kehrl J; Altan-Bonnet G; Altan-Bonnet N
    Cell; 2020 Dec; 183(6):1520-1535.e14. PubMed ID: 33157038
    [TBL] [Abstract][Full Text] [Related]  

  • 7. SARS-CoV-2 viroporin encoded by ORF3a triggers the NLRP3 inflammatory pathway.
    Xu H; Akinyemi IA; Chitre SA; Loeb JC; Lednicky JA; McIntosh MT; Bhaduri-McIntosh S
    Virology; 2022 Mar; 568():13-22. PubMed ID: 35066302
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pathogenic perspective of missense mutations of ORF3a protein of SARS-CoV-2.
    Hassan SS; Attrish D; Ghosh S; Choudhury PP; Roy B
    Virus Res; 2021 Jul; 300():198441. PubMed ID: 33940003
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Endoplasmic reticulum-associated SARS-CoV-2 ORF3a elicits heightened cytopathic effects despite robust ER-associated degradation.
    Zhang J; Cruz-Cosme R; Zhang C; Liu D; Tang Q; Zhao RY
    mBio; 2024 Jan; 15(1):e0303023. PubMed ID: 38078754
    [TBL] [Abstract][Full Text] [Related]  

  • 10. SARS-CoV-2 ORF3a expression in brain disrupts the autophagy-lysosomal pathway, impairs sphingolipid homeostasis, and drives neuropathogenesis.
    Zhu H; Byrnes C; Lee YT; Tuymetova G; Duffy HBD; Bakir JY; Pettit SN; Angina J; Springer DA; Allende ML; Kono M; Proia RL
    FASEB J; 2023 May; 37(5):e22919. PubMed ID: 37071464
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The role of lysosomes as intermediates in betacoronavirus PHEV egress from nerve cells.
    Wang Z; He W; Li C; Chen Y; Li Z; Jiao Y; Zhang J; Shi J; Wang G; Guan J; Zhao K; Song D; Gao F; Lan Y
    J Virol; 2023 Dec; 97(12):e0133823. PubMed ID: 38009916
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Manipulation of autophagy by SARS-CoV-2 proteins.
    Koepke L; Hirschenberger M; Hayn M; Kirchhoff F; Sparrer KM
    Autophagy; 2021 Sep; 17(9):2659-2661. PubMed ID: 34281462
    [TBL] [Abstract][Full Text] [Related]  

  • 13. SARS-CoV-2 ORF3a induces RETREG1/FAM134B-dependent reticulophagy and triggers sequential ER stress and inflammatory responses during SARS-CoV-2 infection.
    Zhang X; Yang Z; Pan T; Long X; Sun Q; Wang PH; Li X; Kuang E
    Autophagy; 2022 Nov; 18(11):2576-2592. PubMed ID: 35239449
    [TBL] [Abstract][Full Text] [Related]  

  • 14. SARS-CoV-2 ORF3a inhibits cGAS-STING-mediated autophagy flux and antiviral function.
    Su J; Shen S; Hu Y; Chen S; Cheng L; Cai Y; Wei W; Wang Y; Rui Y; Yu XF
    J Med Virol; 2023 Jan; 95(1):e28175. PubMed ID: 36163413
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Glycyrrhizin prevents SARS-CoV-2 S1 and Orf3a induced high mobility group box 1 (HMGB1) release and inhibits viral replication.
    Gowda P; Patrick S; Joshi SD; Kumawat RK; Sen E
    Cytokine; 2021 Jun; 142():155496. PubMed ID: 33773396
    [TBL] [Abstract][Full Text] [Related]  

  • 16. HIF-1α promotes SARS-CoV-2 infection and aggravates inflammatory responses to COVID-19.
    Tian M; Liu W; Li X; Zhao P; Shereen MA; Zhu C; Huang S; Liu S; Yu X; Yue M; Pan P; Wang W; Li Y; Chen X; Wu K; Luo Z; Zhang Q; Wu J
    Signal Transduct Target Ther; 2021 Aug; 6(1):308. PubMed ID: 34408131
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Monoclonal Human Antibodies That Recognise the Exposed N and C Terminal Regions of the Often-Overlooked SARS-CoV-2 ORF3a Transmembrane Protein.
    Tan TH; Patton E; Munro CA; Corzo-Leon DE; Porter AJ; Palliyil S
    Viruses; 2021 Nov; 13(11):. PubMed ID: 34835009
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Lysosomal trafficking mediated by Arl8b and BORC promotes invasion of cancer cells that survive radiation.
    Wu PH; Onodera Y; Giaccia AJ; Le QT; Shimizu S; Shirato H; Nam JM
    Commun Biol; 2020 Oct; 3(1):620. PubMed ID: 33110168
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The importance of accessory protein variants in the pathogenicity of SARS-CoV-2.
    Hassan SS; Choudhury PP; Dayhoff GW; Aljabali AAA; Uhal BD; Lundstrom K; Rezaei N; Pizzol D; Adadi P; Lal A; Soares A; Mohamed Abd El-Aziz T; Brufsky AM; Azad GK; Sherchan SP; Baetas-da-Cruz W; Takayama K; Serrano-Aroca Ã; Chauhan G; Palu G; Mishra YK; Barh D; Santana Silva RJ; Andrade BS; Azevedo V; Góes-Neto A; Bazan NG; Redwan EM; Tambuwala M; Uversky VN
    Arch Biochem Biophys; 2022 Mar; 717():109124. PubMed ID: 35085577
    [TBL] [Abstract][Full Text] [Related]  

  • 20. SARS-CoV-2 ORF3a-Mediated NF-κB Activation Is Not Dependent on TRAF-Binding Sequence.
    Busscher BM; Befekadu HB; Liu Z; Xiao TS
    Viruses; 2023 Nov; 15(11):. PubMed ID: 38005906
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.