BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

126 related articles for article (PubMed ID: 34710668)

  • 1. Growing the molecular architecture of imidazole-like ligands in HO-1 complexes.
    Floresta G; Fallica AN; Salerno L; Sorrenti V; Pittalà V; Rescifina A
    Bioorg Chem; 2021 Dec; 117():105428. PubMed ID: 34710668
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Development of new HO-1 inhibitors by a thorough scaffold-hopping analysis.
    Floresta G; Pittalà V; Sorrenti V; Romeo G; Salerno L; Rescifina A
    Bioorg Chem; 2018 Dec; 81():334-339. PubMed ID: 30189413
    [TBL] [Abstract][Full Text] [Related]  

  • 3. From Far West to East: Joining the Molecular Architecture of Imidazole-like Ligands in HO-1 Complexes.
    Floresta G; Fallica AN; Patamia V; Sorrenti V; Greish K; Rescifina A; Pittalà V
    Pharmaceuticals (Basel); 2021 Dec; 14(12):. PubMed ID: 34959690
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Heme oxygenase inhibition by 2-oxy-substituted 1-(1H-imidazol-1-yl)-4-phenylbutanes: effect of halogen substitution in the phenyl ring.
    Roman G; Riley JG; Vlahakis JZ; Kinobe RT; Brien JF; Nakatsu K; Szarek WA
    Bioorg Med Chem; 2007 May; 15(9):3225-34. PubMed ID: 17339115
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Novel imidazole derivatives as heme oxygenase-1 (HO-1) and heme oxygenase-2 (HO-2) inhibitors and their cytotoxic activity in human-derived cancer cell lines.
    Salerno L; Pittalà V; Romeo G; Modica MN; Marrazzo A; Siracusa MA; Sorrenti V; Di Giacomo C; Vanella L; Parayath NN; Greish K
    Eur J Med Chem; 2015; 96():162-72. PubMed ID: 25874340
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Differential inhibition of rat and mouse microsome heme oxygenase by derivatives of imidazole and benzimidazole.
    Hum M; McLaughlin BE; Kong X; Vlahakis JZ; Vukomanovic D; Szarek WA; Nakatsu K
    Can J Physiol Pharmacol; 2017 Dec; 95(12):1454-1461. PubMed ID: 28793202
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of a potent heme oxygenase-2 (HO-2) inhibitor by targeting the secondary hydrophobic pocket of the HO-2 western region.
    Floresta G; Fallica AN; Romeo G; Sorrenti V; Salerno L; Rescifina A; Pittalà V
    Bioorg Chem; 2020 Nov; 104():104310. PubMed ID: 33010625
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Evaluation of novel aryloxyalkyl derivatives of imidazole and 1,2,4-triazole as heme oxygenase-1 (HO-1) inhibitors and their antitumor properties.
    Salerno L; Pittalà V; Romeo G; Modica MN; Siracusa MA; Di Giacomo C; Acquaviva R; Barbagallo I; Tibullo D; Sorrenti V
    Bioorg Med Chem; 2013 Sep; 21(17):5145-53. PubMed ID: 23867390
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and evaluation of imidazole-dioxolane compounds as selective heme oxygenase inhibitors: effect of substituents at the 4-position of the dioxolane ring.
    Vlahakis JZ; Hum M; Rahman MN; Jia Z; Nakatsu K; Szarek WA
    Bioorg Med Chem; 2009 Mar; 17(6):2461-75. PubMed ID: 19268600
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Fourfold Filtered Statistical/Computational Approach for the Identification of Imidazole Compounds as HO-1 Inhibitors from Natural Products.
    Floresta G; Amata E; Gentile D; Romeo G; Marrazzo A; Pittalà V; Salerno L; Rescifina A
    Mar Drugs; 2019 Feb; 17(2):. PubMed ID: 30759842
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Imidazole-dioxolane compounds as isozyme-selective heme oxygenase inhibitors.
    Vlahakis JZ; Kinobe RT; Bowers RJ; Brien JF; Nakatsu K; Szarek WA
    J Med Chem; 2006 Jul; 49(14):4437-41. PubMed ID: 16821802
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effectiveness of novel imidazole-dioxolane heme oxygenase inhibitors in renal proximal tubule epithelial cells.
    Kinobe RT; Ji Y; Vlahakis JZ; Motterlini R; Brien JF; Szarek WA; Nakatsu K
    J Pharmacol Exp Ther; 2007 Dec; 323(3):763-70. PubMed ID: 17761847
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Recombinant truncated and microsomal heme oxygenase-1 and -2: differential sensitivity to inhibitors.
    Vukomanovic D; McLaughlin B; Rahman MN; Vlahakis JZ; Roman G; Dercho RA; Kinobe RT; Hum M; Brien JF; Jia Z; Szarek WA; Nakatsu K
    Can J Physiol Pharmacol; 2010 Apr; 88(4):480-6. PubMed ID: 20555417
    [TBL] [Abstract][Full Text] [Related]  

  • 14. How does binding of imidazole-based inhibitors to heme oxygenase-1 influence their conformation? Insights combining crystal structures and molecular modelling.
    Carletta A; Tilborg A; Moineaux L; de Ruyck J; Basile L; Salerno L; Romeo G; Wouters J; Guccione S
    Acta Crystallogr B Struct Sci Cryst Eng Mater; 2015 Aug; 71(Pt 4):447-54. PubMed ID: 26208625
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors.
    Intagliata S; Salerno L; Ciaffaglione V; Leonardi C; Fallica AN; Carota G; Amata E; Marrazzo A; Pittalà V; Romeo G
    Eur J Med Chem; 2019 Dec; 183():111703. PubMed ID: 31550661
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Immune Modulation by Inhibitors of the HO System.
    Fernández-Fierro A; Funes SC; Rios M; Covián C; González J; Kalergis AM
    Int J Mol Sci; 2020 Dec; 22(1):. PubMed ID: 33396647
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent
    Fallica AN; Sorrenti V; D'Amico AG; Salerno L; Romeo G; Intagliata S; Consoli V; Floresta G; Rescifina A; D'Agata V; Vanella L; Pittalà V
    J Med Chem; 2021 Sep; 64(18):13373-13393. PubMed ID: 34472337
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Selective inhibition of heme oxygenase-2 activity by analogs of 1-(4-chlorobenzyl)-2-(pyrrolidin-1-ylmethyl)-1H-benzimidazole (clemizole): Exploration of the effects of substituents at the N-1 position.
    Vlahakis JZ; Vukomanovic D; Nakatsu K; Szarek WA
    Bioorg Med Chem; 2013 Nov; 21(21):6788-95. PubMed ID: 24021581
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and evaluation of azalanstat analogues as heme oxygenase inhibitors.
    Vlahakis JZ; Kinobe RT; Bowers RJ; Brien JF; Nakatsu K; Szarek WA
    Bioorg Med Chem Lett; 2005 Mar; 15(5):1457-61. PubMed ID: 15713406
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Heme Oxygenase Database (HemeOxDB) and QSAR Analysis of Isoform 1 Inhibitors.
    Amata E; Marrazzo A; Dichiara M; Modica MN; Salerno L; Prezzavento O; Nastasi G; Rescifina A; Romeo G; Pittalà V
    ChemMedChem; 2017 Nov; 12(22):1873-1881. PubMed ID: 28708269
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.