160 related articles for article (PubMed ID: 34710812)
1. Computational algorithmic and molecular dynamics study of functional and structural impacts of non-synonymous single nucleotide polymorphisms in human DHFR gene.
Alam MS; Saleh MA; Mozibullah M; Riham AT; Solayman M; Gan SH
Comput Biol Chem; 2021 Dec; 95():107587. PubMed ID: 34710812
[TBL] [Abstract][Full Text] [Related]
2. Computational identification and analysis of deleterious non-synonymous single nucleotide polymorphisms (nsSNPs) in the human
Kumar R; Jayaraman M; Ramadas K; Chandrasekaran A
J Biomol Struct Dyn; 2024; 42(3):1518-1532. PubMed ID: 37173831
[TBL] [Abstract][Full Text] [Related]
3. Computational SNP Analysis and Molecular Simulation Revealed the Most Deleterious Missense Variants in the NBD1 Domain of Human ABCA1 Transporter.
Dash R; Ali MC; Rana ML; Munni YA; Barua L; Jahan I; Haque MF; Hannan MA; Moon IS
Int J Mol Sci; 2020 Oct; 21(20):. PubMed ID: 33066695
[TBL] [Abstract][Full Text] [Related]
4. Assessment of structurally and functionally high-risk nsSNPs impacts on human bone morphogenetic protein receptor type IA (BMPR1A) by computational approach.
Islam MJ; Parves MR; Mahmud S; Tithi FA; Reza MA
Comput Biol Chem; 2019 Jun; 80():31-45. PubMed ID: 30884445
[TBL] [Abstract][Full Text] [Related]
5. Extrapolating the effect of deleterious nsSNPs in the binding adaptability of flavopiridol with CDK7 protein: a molecular dynamics approach.
George Priya Doss C; Nagasundaram N; Chakraborty C; Chen L; Zhu H
Hum Genomics; 2013 Apr; 7(1):10. PubMed ID: 23561625
[TBL] [Abstract][Full Text] [Related]
6. Increased substrate affinity in the Escherichia coli L28R dihydrofolate reductase mutant causes trimethoprim resistance.
Abdizadeh H; Tamer YT; Acar O; Toprak E; Atilgan AR; Atilgan C
Phys Chem Chem Phys; 2017 May; 19(18):11416-11428. PubMed ID: 28422217
[TBL] [Abstract][Full Text] [Related]
7. Identification and structural characterization of deleterious non-synonymous single nucleotide polymorphisms in the human SKP2 gene.
Hosen SMZ; Dash R; Junaid M; Mitra S; Absar N
Comput Biol Chem; 2019 Apr; 79():127-136. PubMed ID: 30802828
[TBL] [Abstract][Full Text] [Related]
8. Comprehensive Characterization of the Coding and Non-Coding Single Nucleotide Polymorphisms in the Tumor Protein p63 (TP63) Gene Using In Silico Tools.
Akter S; Hossain S; Ali MA; Hosen MI; Shekhar HU
Biomolecules; 2021 Nov; 11(11):. PubMed ID: 34827731
[TBL] [Abstract][Full Text] [Related]
9. In Silico Study Identified Methotrexate Analog as Potential Inhibitor of Drug Resistant Human Dihydrofolate Reductase for Cancer Therapeutics.
Rana RM; Rampogu S; Abid NB; Zeb A; Parate S; Lee G; Yoon S; Kim Y; Kim D; Lee KW
Molecules; 2020 Jul; 25(15):. PubMed ID: 32752079
[TBL] [Abstract][Full Text] [Related]
10. Identification of the most damaging nsSNPs in the human CFL1 gene and their functional and structural impacts on cofilin-1 protein.
Halder SK; Rafi MO; Shahriar EB; Albogami S; El-Shehawi AM; Daullah SMMU; Himel MK; Emran TB
Gene; 2022 Apr; 819():146206. PubMed ID: 35092861
[TBL] [Abstract][Full Text] [Related]
11. First three-dimensional structure of Toxoplasma gondii thymidylate synthase-dihydrofolate reductase: insights for catalysis, interdomain interactions, and substrate channeling.
Sharma H; Landau MJ; Vargo MA; Spasov KA; Anderson KS
Biochemistry; 2013 Oct; 52(41):7305-7317. PubMed ID: 24053355
[TBL] [Abstract][Full Text] [Related]
12. Structural investigation of deleterious non-synonymous SNPs of EGFR gene.
Raghav D; Sharma V; Agarwal SM
Interdiscip Sci; 2013 Mar; 5(1):60-8. PubMed ID: 23605641
[TBL] [Abstract][Full Text] [Related]
13. In silico analyses of Wnt1 nsSNPs reveal structurally destabilizing variants, altered interactions with Frizzled receptors and its deregulation in tumorigenesis.
Mondal A; Paul D; Dastidar SG; Saha T; Goswami AM
Sci Rep; 2022 Sep; 12(1):14934. PubMed ID: 36056132
[TBL] [Abstract][Full Text] [Related]
14. Human dihydrofolate reductase and thymidylate synthase form a complex in vitro and co-localize in normal and cancer cells.
Antosiewicz A; Jarmuła A; Przybylska D; Mosieniak G; Szczepanowska J; Kowalkowska A; Rode W; Cieśla J
J Biomol Struct Dyn; 2017 May; 35(7):1474-1490. PubMed ID: 27187663
[TBL] [Abstract][Full Text] [Related]
15. Computational analysis for the determination of deleterious nsSNPs in human MTHFR gene.
Desai M; Chauhan JB
Comput Biol Chem; 2018 Jun; 74():20-30. PubMed ID: 29524840
[TBL] [Abstract][Full Text] [Related]
16. Computational identification of pathogenic associated nsSNPs and its structural impact in UROD gene: a molecular dynamics approach.
Doss CG; Magesh R
Cell Biochem Biophys; 2014 Nov; 70(2):735-46. PubMed ID: 24777812
[TBL] [Abstract][Full Text] [Related]
17. Predicting the functional and structural consequences of nsSNPs in human methionine synthase gene using computational tools.
Desai M; Chauhan JB
Syst Biol Reprod Med; 2019 Aug; 65(4):288-300. PubMed ID: 30676783
[TBL] [Abstract][Full Text] [Related]
18. Identification of Selective Inhibitors of
Sharma VK; Bharatam PV
J Comput Biol; 2021 Jan; 28(1):43-59. PubMed ID: 32207987
[TBL] [Abstract][Full Text] [Related]
19. Multiple origins of resistance-conferring mutations in Plasmodium vivax dihydrofolate reductase.
Hawkins VN; Auliff A; Prajapati SK; Rungsihirunrat K; Hapuarachchi HC; Maestre A; O'Neil MT; Cheng Q; Joshi H; Na-Bangchang K; Sibley CH
Malar J; 2008 Apr; 7():72. PubMed ID: 18442404
[TBL] [Abstract][Full Text] [Related]
20. The Transgenic Zebrafish Display Fluorescence Reflecting the Expressional Dynamics of Dihydrofolate Reductase.
Chang WN; Chi WY; Kao TT; Tsai JN; Liu W; Liang SS; Chiu CC; Chen BH; Fu TF
Zebrafish; 2017 Jun; 14(3):223-235. PubMed ID: 28350247
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
