BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

238 related articles for article (PubMed ID: 34715055)

  • 1. Reprogramming CBX8-PRC1 function with a positive allosteric modulator.
    Suh JL; Bsteh D; Hart B; Si Y; Weaver TM; Pribitzer C; Lau R; Soni S; Ogana H; Rectenwald JM; Norris JL; Cholensky SH; Sagum C; Umana JD; Li D; Hardy B; Bedford MT; Mumenthaler SM; Lenz HJ; Kim YM; Wang GG; Pearce KH; James LI; Kireev DB; Musselman CA; Frye SV; Bell O
    Cell Chem Biol; 2022 Apr; 29(4):555-571.e11. PubMed ID: 34715055
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery and Characterization of a Cellular Potent Positive Allosteric Modulator of the Polycomb Repressive Complex 1 Chromodomain, CBX7.
    Lamb KN; Bsteh D; Dishman SN; Moussa HF; Fan H; Stuckey JI; Norris JL; Cholensky SH; Li D; Wang J; Sagum C; Stanton BZ; Bedford MT; Pearce KH; Kenakin TP; Kireev DB; Wang GG; James LI; Bell O; Frye SV
    Cell Chem Biol; 2019 Oct; 26(10):1365-1379.e22. PubMed ID: 31422906
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Optimization of Ligands Using Focused DNA-Encoded Libraries To Develop a Selective, Cell-Permeable CBX8 Chromodomain Inhibitor.
    Wang S; Denton KE; Hobbs KF; Weaver T; McFarlane JMB; Connelly KE; Gignac MC; Milosevich N; Hof F; Paci I; Musselman CA; Dykhuizen EC; Krusemark CJ
    ACS Chem Biol; 2020 Jan; 15(1):112-131. PubMed ID: 31755685
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Principles of assembly and regulation of condensates of Polycomb repressive complex 1 through phase separation.
    Brown K; Chew PY; Ingersoll S; Espinosa JR; Aguirre A; Espinoza A; Wen J; Astatike K; Kutateladze TG; Collepardo-Guevara R; Ren X
    Cell Rep; 2023 Oct; 42(10):113136. PubMed ID: 37756159
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A Cbx8-containing polycomb complex facilitates the transition to gene activation during ES cell differentiation.
    Creppe C; Palau A; Malinverni R; Valero V; Buschbeck M
    PLoS Genet; 2014 Dec; 10(12):e1004851. PubMed ID: 25500566
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Nuclear condensates of the Polycomb protein chromobox 2 (CBX2) assemble through phase separation.
    Tatavosian R; Kent S; Brown K; Yao T; Duc HN; Huynh TN; Zhen CY; Ma B; Wang H; Ren X
    J Biol Chem; 2019 Feb; 294(5):1451-1463. PubMed ID: 30514760
    [TBL] [Abstract][Full Text] [Related]  

  • 7. CBX8 promotes lung adenocarcinoma growth and metastasis through transcriptional repression of CDKN2C and SCEL.
    Chen H; Su Y; Yang L; Xi L; Li X; Lan B; Liu M; Xuan C
    J Cell Physiol; 2023 Nov; 238(11):2710-2723. PubMed ID: 37733753
    [TBL] [Abstract][Full Text] [Related]  

  • 8. CBX8 interacts with chromatin PTEN and is involved in regulating mitotic progression.
    Choi BH; Colon TM; Lee E; Kou Z; Dai W
    Cell Prolif; 2021 Nov; 54(11):e13110. PubMed ID: 34592789
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Engagement of DNA and H3K27me3 by the CBX8 chromodomain drives chromatin association.
    Connelly KE; Weaver TM; Alpsoy A; Gu BX; Musselman CA; Dykhuizen EC
    Nucleic Acids Res; 2019 Mar; 47(5):2289-2305. PubMed ID: 30597065
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A Potent, Selective CBX2 Chromodomain Ligand and Its Cellular Activity During Prostate Cancer Neuroendocrine Differentiation.
    Wang S; Alpsoy A; Sood S; Ordonez-Rubiano SC; Dhiman A; Sun Y; Jiao G; Krusemark CJ; Dykhuizen EC
    Chembiochem; 2021 Jul; 22(13):2335-2344. PubMed ID: 33950564
    [TBL] [Abstract][Full Text] [Related]  

  • 11. PRC2.1- and PRC2.2-specific accessory proteins drive recruitment of different forms of canonical PRC1.
    Glancy E; Wang C; Tuck E; Healy E; Amato S; Neikes HK; Mariani A; Mucha M; Vermeulen M; Pasini D; Bracken AP
    Mol Cell; 2023 May; 83(9):1393-1411.e7. PubMed ID: 37030288
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Biological functions of chromobox (CBX) proteins in stem cell self-renewal, lineage-commitment, cancer and development.
    van Wijnen AJ; Bagheri L; Badreldin AA; Larson AN; Dudakovic A; Thaler R; Paradise CR; Wu Z
    Bone; 2021 Feb; 143():115659. PubMed ID: 32979540
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Polycomb Cbx family members mediate the balance between haematopoietic stem cell self-renewal and differentiation.
    Klauke K; Radulović V; Broekhuis M; Weersing E; Zwart E; Olthof S; Ritsema M; Bruggeman S; Wu X; Helin K; Bystrykh L; de Haan G
    Nat Cell Biol; 2013 Apr; 15(4):353-62. PubMed ID: 23502315
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Live-cell single-molecule tracking reveals co-recognition of H3K27me3 and DNA targets polycomb Cbx7-PRC1 to chromatin.
    Zhen CY; Tatavosian R; Huynh TN; Duc HN; Das R; Kokotovic M; Grimm JB; Lavis LD; Lee J; Mejia FJ; Li Y; Yao T; Ren X
    Elife; 2016 Oct; 5():. PubMed ID: 27723458
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Interaction proteomics analysis of polycomb proteins defines distinct PRC1 complexes in mammalian cells.
    Vandamme J; Völkel P; Rosnoblet C; Le Faou P; Angrand PO
    Mol Cell Proteomics; 2011 Apr; 10(4):M110.002642. PubMed ID: 21282530
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PRC1 complex diversity: where is it taking us?
    Gil J; O'Loghlen A
    Trends Cell Biol; 2014 Nov; 24(11):632-41. PubMed ID: 25065329
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PR-DUB preserves Polycomb repression by preventing excessive accumulation of H2Aub1, an antagonist of chromatin compaction.
    Bonnet J; Boichenko I; Kalb R; Le Jeune M; Maltseva S; Pieropan M; Finkl K; Fierz B; Müller J
    Genes Dev; 2022 Oct; 36(19-20):1046-1061. PubMed ID: 36357125
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Polycomb-dependent histone H2A ubiquitination links developmental disorders with cancer.
    Tamburri S; Conway E; Pasini D
    Trends Genet; 2022 Apr; 38(4):333-352. PubMed ID: 34426021
    [TBL] [Abstract][Full Text] [Related]  

  • 19. CBX8, a component of the Polycomb PRC1 complex, modulates DOT1L-mediated gene expression through AF9/MLLT3.
    Malik B; Hemenway CS
    FEBS Lett; 2013 Sep; 587(18):3038-44. PubMed ID: 23891621
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Different polycomb group CBX family proteins associate with distinct regions of chromatin using nonhomologous protein sequences.
    Vincenz C; Kerppola TK
    Proc Natl Acad Sci U S A; 2008 Oct; 105(43):16572-7. PubMed ID: 18927235
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.