BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

138 related articles for article (PubMed ID: 34717963)

  • 1. A novel protoapigenone analog RY10-4 induces apoptosis of breast cancer cells by exacerbating mitochondrial Ca
    Xue P; Chen Q; Ren X; Liu D; Yang X
    Toxicol Appl Pharmacol; 2021 Dec; 433():115776. PubMed ID: 34717963
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A new protoapigenone analog RY10-4 induces apoptosis and suppresses invasion through the PI3K/Akt pathway in human breast cancer.
    Yuan Q; Cai S; Zhang X; Liu Z; Li Z; Luo X; Xiong C; Wang J; Hu J; Ruan J
    Cancer Lett; 2012 Nov; 324(2):210-20. PubMed ID: 22652174
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Combination therapy of RY10-4 with the γ-secretase inhibitor DAPT shows promise in treating HER2-amplified breast cancer.
    Su F; Zhu S; Ruan J; Muftuoglu Y; Zhang L; Yuan Q
    Oncotarget; 2016 Jan; 7(4):4142-54. PubMed ID: 26716652
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A novel protoapigenone analog RY10-4 induces breast cancer MCF-7 cell death through autophagy via the Akt/mTOR pathway.
    Zhang X; Wei H; Liu Z; Yuan Q; Wei A; Shi D; Yang X; Ruan J
    Toxicol Appl Pharmacol; 2013 Jul; 270(2):122-8. PubMed ID: 23624174
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mitochondrial calcium uniporter activity is dispensable for MDA-MB-231 breast carcinoma cell survival.
    Hall DD; Wu Y; Domann FE; Spitz DR; Anderson ME
    PLoS One; 2014; 9(5):e96866. PubMed ID: 24802861
    [TBL] [Abstract][Full Text] [Related]  

  • 6. RY10-4 suppressed metastasis of MDA-MB-231 by stabilizing ECM and E-cadherin.
    Liu Z; Liu Z; Zhang X; Xue P; Zhang H
    Biomed Pharmacother; 2014 May; 68(4):439-45. PubMed ID: 24721328
    [TBL] [Abstract][Full Text] [Related]  

  • 7. RY10-4 Inhibits the Proliferation of Human Hepatocellular Cancer HepG2 Cells by Inducing Apoptosis In Vitro and In Vivo.
    Zhang X; Wang Y; Han S; Xiang H; Peng Y; Wu Y; Pan S; Zhang Y; Ruan J
    PLoS One; 2016; 11(3):e0151679. PubMed ID: 26974964
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Anti-tumor compound RY10-4 suppresses multidrug resistance in MCF-7/ADR cells by inhibiting PI3K/Akt/NF-κB signaling.
    Yang X; Ding Y; Xiao M; Liu X; Ruan J; Xue P
    Chem Biol Interact; 2017 Dec; 278():22-31. PubMed ID: 28987325
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dynamin-related protein 1-mediated mitochondrial fission contributes to IR-783-induced apoptosis in human breast cancer cells.
    Tang Q; Liu W; Zhang Q; Huang J; Hu C; Liu Y; Wang Q; Zhou M; Lai W; Sheng F; Li G; Zhang R
    J Cell Mol Med; 2018 Sep; 22(9):4474-4485. PubMed ID: 29993201
    [TBL] [Abstract][Full Text] [Related]  

  • 10. HINT2 triggers mitochondrial Ca
    Chen L; Sun Q; Zhou D; Song W; Yang Q; Ju B; Zhang L; Xie H; Zhou L; Hu Z; Yao H; Zheng S; Wang W
    Cancer Lett; 2017 Dec; 411():106-116. PubMed ID: 28947137
    [TBL] [Abstract][Full Text] [Related]  

  • 11. MCU-induced mitochondrial calcium uptake promotes mitochondrial biogenesis and colorectal cancer growth.
    Liu Y; Jin M; Wang Y; Zhu J; Tan R; Zhao J; Ji X; Jin C; Jia Y; Ren T; Xing J
    Signal Transduct Target Ther; 2020 May; 5(1):59. PubMed ID: 32371956
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The effect of mitochondrial calcium uniporter and cyclophilin D knockout on resistance of brain mitochondria to Ca
    Hamilton J; Brustovetsky T; Brustovetsky N
    J Biol Chem; 2021; 296():100669. PubMed ID: 33864812
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification and functional validation of FDA-approved positive and negative modulators of the mitochondrial calcium uniporter.
    De Mario A; Tosatto A; Hill JM; Kriston-Vizi J; Ketteler R; Vecellio Reane D; Cortopassi G; Szabadkai G; Rizzuto R; Mammucari C
    Cell Rep; 2021 Jun; 35(12):109275. PubMed ID: 34161774
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Role of mitochondrial calcium uniporter-mediated Ca
    Zhang L; Wang H; Zhou X; Mao L; Ding K; Hu Z
    J Cell Mol Med; 2019 Apr; 23(4):2995-3009. PubMed ID: 30756474
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mitochondrial Ca²⁺ uniporter is critical for store-operated Ca²⁺ entry-dependent breast cancer cell migration.
    Tang S; Wang X; Shen Q; Yang X; Yu C; Cai C; Cai G; Meng X; Zou F
    Biochem Biophys Res Commun; 2015 Feb; 458(1):186-93. PubMed ID: 25640838
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Grifola frondosa polysaccharides induce breast cancer cell apoptosis via the mitochondrial-dependent apoptotic pathway.
    Zhang Y; Sun D; Meng Q; Guo W; Chen Q; Zhang Y
    Int J Mol Med; 2017 Oct; 40(4):1089-1095. PubMed ID: 28765878
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Astragaloside-IV Protects Against Heat-induced Apoptosis by Inhibiting Excessive Activation of Mitochondrial Ca2+ Uniporter.
    Dong Z; Zhang C; Chen Y; Chen Y; Yuan Z; Peng Y; Cao T
    Cell Physiol Biochem; 2017; 42(2):480-494. PubMed ID: 28578342
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A novel compound RY10-4 downregulates P-glycoprotein expression and reverses multidrug-resistant phenotype in human breast cancer MCF-7/ADR cells.
    Xue P; Yang X; Liu Y; Xiong C; Ruan J
    Biomed Pharmacother; 2014 Oct; 68(8):1049-56. PubMed ID: 25455158
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A novel compound RY10-4 induces apoptosis and inhibits invasion via inhibiting STAT3 through ERK-, p38-dependent pathways in human lung adenocarcinoma A549 cells.
    Xue P; Zhao Y; Liu Y; Yuan Q; Xiong C; Ruan J
    Chem Biol Interact; 2014 Feb; 209():25-34. PubMed ID: 24300195
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mitochondrial calcium uniporter silencing potentiates caspase-independent cell death in MDA-MB-231 breast cancer cells.
    Curry MC; Peters AA; Kenny PA; Roberts-Thomson SJ; Monteith GR
    Biochem Biophys Res Commun; 2013 May; 434(3):695-700. PubMed ID: 23602897
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.