182 related articles for article (PubMed ID: 34718441)
1. Tocilizumab suppresses the pro-carcinogenic effects of breast cancer-associated fibroblasts through inhibition of the STAT3/AUF1 pathway.
Al-Jomah N; Al-Mohanna FH; Aboussekhra A
Carcinogenesis; 2021 Dec; 42(12):1439-1448. PubMed ID: 34718441
[TBL] [Abstract][Full Text] [Related]
2. Decorin (DCN) Downregulation Activates Breast Stromal Fibroblasts and Promotes Their Pro-Carcinogenic Effects through the IL-6/STAT3/AUF1 Signaling.
Aljagthmi WA; Alasmari MA; Daghestani MH; Al-Kharashi LA; Al-Mohanna FH; Aboussekhra A
Cells; 2024 Apr; 13(8):. PubMed ID: 38667295
[TBL] [Abstract][Full Text] [Related]
3. Cucurbitacin I (JSI-124)-dependent inhibition of STAT3 permanently suppresses the pro-carcinogenic effects of active breast cancer-associated fibroblasts.
Al-Harbi B; Aboussekhra A
Mol Carcinog; 2021 Apr; 60(4):242-251. PubMed ID: 33621387
[TBL] [Abstract][Full Text] [Related]
4. The cytokine IL-6 reactivates breast stromal fibroblasts through transcription factor STAT3-dependent up-regulation of the RNA-binding protein AUF1.
Hendrayani SF; Al-Khalaf HH; Aboussekhra A
J Biol Chem; 2014 Nov; 289(45):30962-76. PubMed ID: 25231991
[TBL] [Abstract][Full Text] [Related]
5. Tocilizumab potentiates cisplatin cytotoxicity and targets cancer stem cells in triple-negative breast cancer.
Alraouji NN; Al-Mohanna FH; Ghebeh H; Arafah M; Almeer R; Al-Tweigeri T; Aboussekhra A
Mol Carcinog; 2020 Sep; 59(9):1041-1051. PubMed ID: 32537818
[TBL] [Abstract][Full Text] [Related]
6. The inflammatory/cancer-related IL-6/STAT3/NF-κB positive feedback loop includes AUF1 and maintains the active state of breast myofibroblasts.
Hendrayani SF; Al-Harbi B; Al-Ansari MM; Silva G; Aboussekhra A
Oncotarget; 2016 Jul; 7(27):41974-41985. PubMed ID: 27248826
[TBL] [Abstract][Full Text] [Related]
7. Cancer-associated fibroblasts induce epithelial-mesenchymal transition of bladder cancer cells through paracrine IL-6 signalling.
Goulet CR; Champagne A; Bernard G; Vandal D; Chabaud S; Pouliot F; Bolduc S
BMC Cancer; 2019 Feb; 19(1):137. PubMed ID: 30744595
[TBL] [Abstract][Full Text] [Related]
8. Eugenol modulates genomic methylation and inactivates breast cancer-associated fibroblasts through E2F1-dependent downregulation of DNMT1/DNMT3A.
Al-Kharashi LA; Bakheet T; AlHarbi WA; Al-Moghrabi N; Aboussekhra A
Mol Carcinog; 2021 Nov; 60(11):784-795. PubMed ID: 34473867
[TBL] [Abstract][Full Text] [Related]
9. Epiregulin reprograms cancer-associated fibroblasts and facilitates oral squamous cell carcinoma invasion via JAK2-STAT3 pathway.
Wang Y; Jing Y; Ding L; Zhang X; Song Y; Chen S; Zhao X; Huang X; Pu Y; Wang Z; Ni Y; Hu Q
J Exp Clin Cancer Res; 2019 Jun; 38(1):274. PubMed ID: 31234944
[TBL] [Abstract][Full Text] [Related]
10. Dual STAT‑3 and IL‑6R inhibition with stattic and tocilizumab decreases migration, invasion and proliferation of prostate cancer cells by targeting the IL‑6/IL‑6R/STAT‑3 axis.
Méndez-Clemente A; Bravo-Cuellar A; González-Ochoa S; Santiago-Mercado M; Palafox-Mariscal L; Jave-Suárez L; Solorzano-Ibarra F; Villaseñor-García M; Ortiz-Lazareno P; Hernández-Flores G
Oncol Rep; 2022 Aug; 48(2):. PubMed ID: 35703345
[TBL] [Abstract][Full Text] [Related]
11. Anti-metastatic potential of somatostatin analog SOM230: Indirect pharmacological targeting of pancreatic cancer-associated fibroblasts.
Moatassim-Billah S; Duluc C; Samain R; Jean C; Perraud A; Decaup E; Cassant-Sourdy S; Bakri Y; Selves J; Schmid H; Martineau Y; Mathonnet M; Pyronnet S; Bousquet C
Oncotarget; 2016 Jul; 7(27):41584-41598. PubMed ID: 27177087
[TBL] [Abstract][Full Text] [Related]
12. IL-6/STAT3 axis initiated CAFs via up-regulating TIMP-1 which was attenuated by acetylation of STAT3 induced by PCAF in HCC microenvironment.
Zheng X; Xu M; Yao B; Wang C; Jia Y; Liu Q
Cell Signal; 2016 Sep; 28(9):1314-1324. PubMed ID: 27297362
[TBL] [Abstract][Full Text] [Related]
13. Tumor suppressor HIC1 is synergistically compromised by cancer-associated fibroblasts and tumor cells through the IL-6/pSTAT3 axis in breast cancer.
Sun X; Qu Q; Lao Y; Zhang M; Yin X; Zhu H; Wang Y; Yang J; Yi J; Hao M
BMC Cancer; 2019 Dec; 19(1):1180. PubMed ID: 31795965
[TBL] [Abstract][Full Text] [Related]
14. The IL1β-IL1R signaling is involved in the stimulatory effects triggered by hypoxia in breast cancer cells and cancer-associated fibroblasts (CAFs).
Lappano R; Talia M; Cirillo F; Rigiracciolo DC; Scordamaglia D; Guzzi R; Miglietta AM; De Francesco EM; Belfiore A; Sims AH; Maggiolini M
J Exp Clin Cancer Res; 2020 Aug; 39(1):153. PubMed ID: 32778144
[TBL] [Abstract][Full Text] [Related]
15. Osteoprotegerin (OPG) Upregulation Activates Breast Stromal Fibroblasts and Enhances Their Pro-Carcinogenic Effects through the STAT3/IL-6 Signaling.
Al-Nasrallah HK; Al-Ansari MM; Aboussekhra A
Cells; 2022 Oct; 11(21):. PubMed ID: 36359766
[TBL] [Abstract][Full Text] [Related]
16. TGF-β pathway activation by idiopathic pulmonary fibrosis (IPF) fibroblast derived soluble factors is mediated by IL-6 trans-signaling.
Epstein Shochet G; Brook E; Bardenstein-Wald B; Shitrit D
Respir Res; 2020 Feb; 21(1):56. PubMed ID: 32070329
[TBL] [Abstract][Full Text] [Related]
17. p16(INK4A) represses the paracrine tumor-promoting effects of breast stromal fibroblasts.
Al-Ansari MM; Hendrayani SF; Shehata AI; Aboussekhra A
Oncogene; 2013 May; 32(18):2356-64. PubMed ID: 22751126
[TBL] [Abstract][Full Text] [Related]
18. Metformin suppresses HIF-1α expression in cancer-associated fibroblasts to prevent tumor-stromal cross talk in breast cancer.
Shao S; Zhao L; An G; Zhang L; Jing X; Luo M; Li W; Meng D; Ning Q; Zhao X; Lei J
FASEB J; 2020 Aug; 34(8):10860-10870. PubMed ID: 32592239
[TBL] [Abstract][Full Text] [Related]
19. IL-6 Mediates Cross-Talk between Tumor Cells and Activated Fibroblasts in the Tumor Microenvironment.
Karakasheva TA; Lin EW; Tang Q; Qiao E; Waldron TJ; Soni M; Klein-Szanto AJ; Sahu V; Basu D; Ohashi S; Baba K; Giaccone ZT; Walker SR; Frank DA; Wileyto EP; Long Q; Dunagin MC; Raj A; Diehl JA; Wong KK; Bass AJ; Rustgi AK
Cancer Res; 2018 Sep; 78(17):4957-4970. PubMed ID: 29976575
[TBL] [Abstract][Full Text] [Related]
20. Cancer-associated fibroblasts induce an aggressive phenotypic shift in non-malignant breast epithelial cells via interleukin-8 and S100A8.
Lim H; Koh M; Jin H; Bae M; Lee SY; Kim KM; Jung J; Kim HJ; Park SY; Kim HS; Moon WK; Hwang S; Cho NH; Moon A
J Cell Physiol; 2021 Oct; 236(10):7014-7032. PubMed ID: 33748944
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]