165 related articles for article (PubMed ID: 34719594)
1. Discovery of DS68702229 as a Potent, Orally Available NAMPT (Nicotinamide Phosphoribosyltransferase) Activator.
Akiu M; Tsuji T; Iida K; Sogawa Y; Terayama K; Yokoyama M; Tanaka J; Asano D; Honda T; Sakurai K; Pinkerton AB; Nakamura T
Chem Pharm Bull (Tokyo); 2021; 69(11):1110-1122. PubMed ID: 34719594
[TBL] [Abstract][Full Text] [Related]
2. Discovery of 1-[2-(1-methyl-1H-pyrazol-5-yl)-[1,2,4]triazolo[1,5-a]pyridin-6-yl]-3-(pyridin-4-ylmethyl)urea as a potent NAMPT (nicotinamide phosphoribosyltransferase) activator with attenuated CYP inhibition.
Akiu M; Tsuji T; Sogawa Y; Terayama K; Yokoyama M; Tanaka J; Asano D; Sakurai K; Sergienko E; Sessions EH; Gardell SJ; Pinkerton AB; Nakamura T
Bioorg Med Chem Lett; 2021 Jul; 43():128048. PubMed ID: 33887438
[TBL] [Abstract][Full Text] [Related]
3. Optimization of a urea-containing series of nicotinamide phosphoribosyltransferase (NAMPT) activators.
Pinkerton AB; Sessions EH; Hershberger P; Maloney PR; Peddibhotla S; Hopf M; Sergienko E; Ma CT; Smith LH; Jackson MR; Tanaka J; Tsuji T; Akiu M; Cohen SE; Nakamura T; Gardell SJ
Bioorg Med Chem Lett; 2021 Jun; 41():128007. PubMed ID: 33798699
[TBL] [Abstract][Full Text] [Related]
4. Nicotinamide Phosphoribosyltransferase (Nampt)/Nicotinamide Adenine Dinucleotide (NAD) Axis Suppresses Atrial Fibrillation by Modulating the Calcium Handling Pathway.
Feng D; Xu D; Murakoshi N; Tajiri K; Qin R; Yonebayashi S; Okabe Y; Li S; Yuan Z; Aonuma K; Ieda M
Int J Mol Sci; 2020 Jun; 21(13):. PubMed ID: 32629939
[TBL] [Abstract][Full Text] [Related]
5. Tripeptide IRW Upregulates NAMPT Protein Levels in Cells and Obese C57BL/6J Mice.
Bhullar KS; Son M; Kerek E; Cromwell CR; Wingert BM; Wu K; Jovel J; Camacho CJ; Hubbard BP; Wu J
J Agric Food Chem; 2021 Feb; 69(5):1555-1566. PubMed ID: 33522796
[TBL] [Abstract][Full Text] [Related]
6. Discovery of small-molecule activators of nicotinamide phosphoribosyltransferase (NAMPT) and their preclinical neuroprotective activity.
Yao H; Liu M; Wang L; Zu Y; Wu C; Li C; Zhang R; Lu H; Li F; Xi S; Chen S; Gu X; Liu T; Cai J; Wang S; Yang M; Xing GG; Xiong W; Hua L; Tang Y; Wang G
Cell Res; 2022 Jun; 32(6):570-584. PubMed ID: 35459935
[TBL] [Abstract][Full Text] [Related]
7. Nampt: linking NAD biology, metabolism and cancer.
Garten A; Petzold S; Körner A; Imai S; Kiess W
Trends Endocrinol Metab; 2009 Apr; 20(3):130-8. PubMed ID: 19109034
[TBL] [Abstract][Full Text] [Related]
8. Inhibition of nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enzyme of the nicotinamide adenine dinucleotide (NAD) salvage pathway, to target glioma heterogeneity through mitochondrial oxidative stress.
Sharma P; Xu J; Williams K; Easley M; Elder JB; Lonser R; Lang FF; Lapalombella R; Sampath D; Puduvalli VK
Neuro Oncol; 2022 Feb; 24(2):229-244. PubMed ID: 34260721
[TBL] [Abstract][Full Text] [Related]
9. Synthesis, Optimization, and Structure-Activity Relationships of Nicotinamide Phosphoribosyltransferase (NAMPT) Positive Allosteric Modulators (N-PAMs).
Shen Z; Ratia K; Krider I; Ackerman-Berrier M; Penton C; Musku SR; Gordon-Blake JM; Laham MS; Christie N; Ma N; Fu J; Xiong R; Courey JM; Velma GR; Thatcher GRJ
J Med Chem; 2023 Dec; 66(24):16704-16727. PubMed ID: 38096366
[TBL] [Abstract][Full Text] [Related]
10. Boosting NAD
Gardell SJ; Hopf M; Khan A; Dispagna M; Hampton Sessions E; Falter R; Kapoor N; Brooks J; Culver J; Petucci C; Ma CT; Cohen SE; Tanaka J; Burgos ES; Hirschi JS; Smith SR; Sergienko E; Pinkerton AB
Nat Commun; 2019 Jul; 10(1):3241. PubMed ID: 31324777
[TBL] [Abstract][Full Text] [Related]
11. Depletion of NAD pool contributes to impairment of endothelial progenitor cell mobilization in diabetes.
Wang P; Yang X; Zhang Z; Song J; Guan YF; Zou DJ; Miao CY
Metabolism; 2016 Jun; 65(6):852-62. PubMed ID: 27173464
[TBL] [Abstract][Full Text] [Related]
12. NAMPT-mediated NAD
Nielsen KN; Peics J; Ma T; Karavaeva I; Dall M; Chubanava S; Basse AL; Dmytriyeva O; Treebak JT; Gerhart-Hines Z
Mol Metab; 2018 May; 11():178-188. PubMed ID: 29551635
[TBL] [Abstract][Full Text] [Related]
13. Nicotinamide phosphoribosyltransferase (Nampt) in carcinogenesis: new clinical opportunities.
Chen H; Wang S; Zhang H; Nice EC; Huang C
Expert Rev Anticancer Ther; 2016 Aug; 16(8):827-38. PubMed ID: 27186719
[TBL] [Abstract][Full Text] [Related]
14. Identification of small-molecule urea derivatives as novel NAMPT inhibitors via pharmacophore-based virtual screening.
Ozgencil F; Eren G; Ozkan Y; Guntekin-Ergun S; Cetin-Atalay R
Bioorg Med Chem; 2020 Jan; 28(1):115217. PubMed ID: 31818629
[TBL] [Abstract][Full Text] [Related]
15. A nicotinamide phosphoribosyltransferase-GAPDH interaction sustains the stress-induced NMN/NAD
Grolla AA; Miggiano R; Di Marino D; Bianchi M; Gori A; Orsomando G; Gaudino F; Galli U; Del Grosso E; Mazzola F; Angeletti C; Guarneri M; Torretta S; Calabrò M; Boumya S; Fan X; Colombo G; Travelli C; Rocchio F; Aronica E; Wohlschlegel JA; Deaglio S; Rizzi M; Genazzani AA; Garavaglia S
J Biol Chem; 2020 Mar; 295(11):3635-3651. PubMed ID: 31988240
[TBL] [Abstract][Full Text] [Related]
16. Nampt and its potential role in inflammation and type 2 diabetes.
Garten A; Petzold S; Schuster S; Körner A; Kratzsch J; Kiess W
Handb Exp Pharmacol; 2011; (203):147-64. PubMed ID: 21484571
[TBL] [Abstract][Full Text] [Related]
17. Both gain and loss of Nampt function promote pressure overload-induced heart failure.
Byun J; Oka SI; Imai N; Huang CY; Ralda G; Zhai P; Ikeda Y; Ikeda S; Sadoshima J
Am J Physiol Heart Circ Physiol; 2019 Oct; 317(4):H711-H725. PubMed ID: 31347918
[TBL] [Abstract][Full Text] [Related]
18. Regenerative Neurogenesis After Ischemic Stroke Promoted by Nicotinamide Phosphoribosyltransferase-Nicotinamide Adenine Dinucleotide Cascade.
Zhao Y; Guan YF; Zhou XM; Li GQ; Li ZY; Zhou CC; Wang P; Miao CY
Stroke; 2015 Jul; 46(7):1966-74. PubMed ID: 26060246
[TBL] [Abstract][Full Text] [Related]
19. Nicotinamide Phosphoribosyltransferase as a Key Molecule of the Aging/Senescence Process.
Khaidizar FD; Bessho Y; Nakahata Y
Int J Mol Sci; 2021 Apr; 22(7):. PubMed ID: 33918226
[TBL] [Abstract][Full Text] [Related]
20. SIRT1 selectively exerts the metabolic protective effects of hepatocyte nicotinamide phosphoribosyltransferase.
Higgins CB; Mayer AL; Zhang Y; Franczyk M; Ballentine S; Yoshino J; DeBosch BJ
Nat Commun; 2022 Feb; 13(1):1074. PubMed ID: 35228549
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]