BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

227 related articles for article (PubMed ID: 34720529)

  • 1. Transcription factors specificity protein and nuclear receptor 4A1 in pancreatic cancer.
    Safe S; Shrestha R; Mohankumar K; Howard M; Hedrick E; Abdelrahim M
    World J Gastroenterol; 2021 Oct; 27(38):6387-6398. PubMed ID: 34720529
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Specificity Proteins (Sp) and Cancer.
    Safe S
    Int J Mol Sci; 2023 Mar; 24(6):. PubMed ID: 36982239
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Specificity protein (Sp) transcription factors Sp1, Sp3 and Sp4 are non-oncogene addiction genes in cancer cells.
    Hedrick E; Cheng Y; Jin UH; Kim K; Safe S
    Oncotarget; 2016 Apr; 7(16):22245-56. PubMed ID: 26967243
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mechanism of metformin-dependent inhibition of mammalian target of rapamycin (mTOR) and Ras activity in pancreatic cancer: role of specificity protein (Sp) transcription factors.
    Nair V; Sreevalsan S; Basha R; Abdelrahim M; Abudayyeh A; Rodrigues Hoffman A; Safe S
    J Biol Chem; 2014 Oct; 289(40):27692-701. PubMed ID: 25143389
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The nuclear orphan receptor NR4A1 regulates β1-integrin expression in pancreatic and colon cancer cells and can be targeted by NR4A1 antagonists.
    Hedrick E; Lee SO; Safe S
    Mol Carcinog; 2017 Sep; 56(9):2066-2075. PubMed ID: 28418095
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Metformin inhibits pancreatic cancer cell and tumor growth and downregulates Sp transcription factors.
    Nair V; Pathi S; Jutooru I; Sreevalsan S; Basha R; Abdelrahim M; Samudio I; Safe S
    Carcinogenesis; 2013 Dec; 34(12):2870-9. PubMed ID: 23803693
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Penfluridol Represses Integrin Expression in Breast Cancer through Induction of Reactive Oxygen Species and Downregulation of Sp Transcription Factors.
    Hedrick E; Li X; Safe S
    Mol Cancer Ther; 2017 Jan; 16(1):205-216. PubMed ID: 27811009
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Curcumin and synthetic analogs induce reactive oxygen species and decreases specificity protein (Sp) transcription factors by targeting microRNAs.
    Gandhy SU; Kim K; Larsen L; Rosengren RJ; Safe S
    BMC Cancer; 2012 Nov; 12():564. PubMed ID: 23194063
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of NFkappaB and pancreatic cancer cell and tumor growth by curcumin is dependent on specificity protein down-regulation.
    Jutooru I; Chadalapaka G; Lei P; Safe S
    J Biol Chem; 2010 Aug; 285(33):25332-44. PubMed ID: 20538607
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Specificity Protein Transcription Factors and Cancer: Opportunities for Drug Development.
    Safe S; Abbruzzese J; Abdelrahim M; Hedrick E
    Cancer Prev Res (Phila); 2018 Jul; 11(7):371-382. PubMed ID: 29545399
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Benzyl Isothiocyanate (BITC) Induces Reactive Oxygen Species-dependent Repression of STAT3 Protein by Down-regulation of Specificity Proteins in Pancreatic Cancer.
    Kasiappan R; Jutooru I; Karki K; Hedrick E; Safe S
    J Biol Chem; 2016 Dec; 291(53):27122-27133. PubMed ID: 27875298
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Broussochalcone A Is a Novel Inhibitor of the Orphan Nuclear Receptor NR4A1 and Induces Apoptosis in Pancreatic Cancer Cells.
    Lee HS; Kim SH; Kim BM; Safe S; Lee SO
    Molecules; 2021 Apr; 26(8):. PubMed ID: 33923503
    [TBL] [Abstract][Full Text] [Related]  

  • 13. MicroRNA-Specificity Protein (Sp) Transcription Factor Interactions and Significance in Carcinogenesis.
    Safe S
    Curr Pharmacol Rep; 2015 Apr; 1(2):73-78. PubMed ID: 26457240
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of rhabdomyosarcoma cell and tumor growth by targeting specificity protein (Sp) transcription factors.
    Chadalapaka G; Jutooru I; Sreevalsan S; Pathi S; Kim K; Chen C; Crose L; Linardic C; Safe S
    Int J Cancer; 2013 Feb; 132(4):795-806. PubMed ID: 22815231
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Induction of the transcriptional repressor ZBTB4 in prostate cancer cells by drug-induced targeting of microRNA-17-92/106b-25 clusters.
    Kim K; Chadalapaka G; Pathi SS; Jin UH; Lee JS; Park YY; Cho SG; Chintharlapalli S; Safe S
    Mol Cancer Ther; 2012 Sep; 11(9):1852-62. PubMed ID: 22752225
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Plant Alkaloid Tetrandrine Is a Nuclear Receptor 4A1 Antagonist and Inhibits Panc-1 Cell Growth In Vitro and In Vivo.
    Lee HS; Kim DH; Lee IS; Park JH; Martin G; Safe S; Kim KJ; Kim JH; Jang BI; Lee SO
    Int J Mol Sci; 2022 May; 23(9):. PubMed ID: 35563670
    [TBL] [Abstract][Full Text] [Related]  

  • 17. NR4A1, 2, 3--an orphan nuclear hormone receptor family involved in cell apoptosis and carcinogenesis.
    Li QX; Ke N; Sundaram R; Wong-Staal F
    Histol Histopathol; 2006 May; 21(5):533-40. PubMed ID: 16493583
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Specificity protein (Sp) transcription factors and metformin regulate expression of the long non-coding RNA HULC.
    Gandhy SU; Imanirad P; Jin UH; Nair V; Hedrick E; Cheng Y; Corton JC; Kim K; Safe S
    Oncotarget; 2015 Sep; 6(28):26359-72. PubMed ID: 26317792
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Piperlongumine is a ligand for the orphan nuclear receptor 4A1 (NR4A1).
    Zhang L; Martin G; Mohankumar K; Wright GA; Mariyam F; Safe S
    Front Pharmacol; 2023; 14():1223153. PubMed ID: 37808182
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The orphan nuclear receptor NR4A1 (Nur77) regulates oxidative and endoplasmic reticulum stress in pancreatic cancer cells.
    Lee SO; Jin UH; Kang JH; Kim SB; Guthrie AS; Sreevalsan S; Lee JS; Safe S
    Mol Cancer Res; 2014 Apr; 12(4):527-538. PubMed ID: 24515801
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.