296 related articles for article (PubMed ID: 34732726)
1. Gain-of-function cardiomyopathic mutations in RBM20 rewire splicing regulation and re-distribute ribonucleoprotein granules within processing bodies.
Fenix AM; Miyaoka Y; Bertero A; Blue SM; Spindler MJ; Tan KKB; Perez-Bermejo JA; Chan AH; Mayerl SJ; Nguyen TD; Russell CR; Lizarraga PP; Truong A; So PL; Kulkarni A; Chetal K; Sathe S; Sniadecki NJ; Yeo GW; Murry CE; Conklin BR; Salomonis N
Nat Commun; 2021 Nov; 12(1):6324. PubMed ID: 34732726
[TBL] [Abstract][Full Text] [Related]
2. Severe DCM phenotype of patient harboring RBM20 mutation S635A can be modeled by patient-specific induced pluripotent stem cell-derived cardiomyocytes.
Streckfuss-Bömeke K; Tiburcy M; Fomin A; Luo X; Li W; Fischer C; Özcelik C; Perrot A; Sossalla S; Haas J; Vidal RO; Rebs S; Khadjeh S; Meder B; Bonn S; Linke WA; Zimmermann WH; Hasenfuss G; Guan K
J Mol Cell Cardiol; 2017 Dec; 113():9-21. PubMed ID: 28941705
[TBL] [Abstract][Full Text] [Related]
3. Modeling structural and functional deficiencies of RBM20 familial dilated cardiomyopathy using human induced pluripotent stem cells.
Wyles SP; Li X; Hrstka SC; Reyes S; Oommen S; Beraldi R; Edwards J; Terzic A; Olson TM; Nelson TJ
Hum Mol Genet; 2016 Jan; 25(2):254-65. PubMed ID: 26604136
[TBL] [Abstract][Full Text] [Related]
4. Precise genomic editing of pathogenic mutations in
Nishiyama T; Zhang Y; Cui M; Li H; Sanchez-Ortiz E; McAnally JR; Tan W; Kim J; Chen K; Xu L; Bassel-Duby R; Olson EN
Sci Transl Med; 2022 Nov; 14(672):eade1633. PubMed ID: 36417486
[TBL] [Abstract][Full Text] [Related]
5. A missense mutation in the RSRSP stretch of Rbm20 causes dilated cardiomyopathy and atrial fibrillation in mice.
Ihara K; Sasano T; Hiraoka Y; Togo-Ohno M; Soejima Y; Sawabe M; Tsuchiya M; Ogawa H; Furukawa T; Kuroyanagi H
Sci Rep; 2020 Oct; 10(1):17894. PubMed ID: 33110103
[TBL] [Abstract][Full Text] [Related]
6. The Combined Human Genotype of Truncating
Gaertner A; Bloebaum J; Brodehl A; Klauke B; Sielemann K; Kassner A; Fox H; Morshuis M; Tiesmeier J; Schulz U; Knoell R; Gummert J; Milting H
Genes (Basel); 2021 Jun; 12(6):. PubMed ID: 34201072
[TBL] [Abstract][Full Text] [Related]
7. Generation of an RBM20-mutation-associated left-ventricular non-compaction cardiomyopathy iPSC line (UMGi255-A) into a DCM genetic background to investigate monogenetic cardiomyopathies.
Eberl H; Rebs S; Hoppe S; Sedaghat-Hamedani F; Kayvanpour E; Meder B; Streckfuss-Bömeke K
Stem Cell Res; 2024 Feb; 74():103290. PubMed ID: 38141360
[TBL] [Abstract][Full Text] [Related]
8. iPSC Modeling of RBM20-Deficient DCM Identifies Upregulation of RBM20 as a Therapeutic Strategy.
Briganti F; Sun H; Wei W; Wu J; Zhu C; Liss M; Karakikes I; Rego S; Cipriano A; Snyder M; Meder B; Xu Z; Millat G; Gotthardt M; Mercola M; Steinmetz LM
Cell Rep; 2020 Sep; 32(10):108117. PubMed ID: 32905764
[TBL] [Abstract][Full Text] [Related]
9. Disruption of the nuclear localization signal in RBM20 is causative in dilated cardiomyopathy.
Zhang Y; Gregorich ZR; Wang Y; Braz CU; Zhang J; Liu Y; Liu P; Shen J; Aori N; Hacker TA; Granzier H; Guo W
JCI Insight; 2023 Jul; 8(13):. PubMed ID: 37219949
[TBL] [Abstract][Full Text] [Related]
10. A mutation in the glutamate-rich region of RNA-binding motif protein 20 causes dilated cardiomyopathy through missplicing of titin and impaired Frank-Starling mechanism.
Beqqali A; Bollen IA; Rasmussen TB; van den Hoogenhof MM; van Deutekom HW; Schafer S; Haas J; Meder B; Sørensen KE; van Oort RJ; Mogensen J; Hubner N; Creemers EE; van der Velden J; Pinto YM
Cardiovasc Res; 2016 Oct; 112(1):452-63. PubMed ID: 27496873
[TBL] [Abstract][Full Text] [Related]
11. RBM20 Mutations Induce an Arrhythmogenic Dilated Cardiomyopathy Related to Disturbed Calcium Handling.
van den Hoogenhof MMG; Beqqali A; Amin AS; van der Made I; Aufiero S; Khan MAF; Schumacher CA; Jansweijer JA; van Spaendonck-Zwarts KY; Remme CA; Backs J; Verkerk AO; Baartscheer A; Pinto YM; Creemers EE
Circulation; 2018 Sep; 138(13):1330-1342. PubMed ID: 29650543
[TBL] [Abstract][Full Text] [Related]
12. The Acetylation of Lysine-376 of G3BP1 Regulates RNA Binding and Stress Granule Dynamics.
Gal J; Chen J; Na DY; Tichacek L; Barnett KR; Zhu H
Mol Cell Biol; 2019 Nov; 39(22):. PubMed ID: 31481451
[TBL] [Abstract][Full Text] [Related]
13. RNA-binding protein RBM20 represses splicing to orchestrate cardiac pre-mRNA processing.
Maatz H; Jens M; Liss M; Schafer S; Heinig M; Kirchner M; Adami E; Rintisch C; Dauksaite V; Radke MH; Selbach M; Barton PJ; Cook SA; Rajewsky N; Gotthardt M; Landthaler M; Hubner N
J Clin Invest; 2014 Aug; 124(8):3419-30. PubMed ID: 24960161
[TBL] [Abstract][Full Text] [Related]
14. Rbm20-deficient cardiogenesis reveals early disruption of RNA processing and sarcomere remodeling establishing a developmental etiology for dilated cardiomyopathy.
Beraldi R; Li X; Martinez Fernandez A; Reyes S; Secreto F; Terzic A; Olson TM; Nelson TJ
Hum Mol Genet; 2014 Jul; 23(14):3779-91. PubMed ID: 24584570
[TBL] [Abstract][Full Text] [Related]
15. Dysregulated ribonucleoprotein granules promote cardiomyopathy in RBM20 gene-edited pigs.
Schneider JW; Oommen S; Qureshi MY; Goetsch SC; Pease DR; Sundsbak RS; Guo W; Sun M; Sun H; Kuroyanagi H; Webster DA; Coutts AW; Holst KA; Edwards BS; Newville N; Hathcock MA; Melkamu T; Briganti F; Wei W; Romanelli MG; Fahrenkrug SC; Frantz DE; Olson TM; Steinmetz LM; Carlson DF; Nelson TJ;
Nat Med; 2020 Nov; 26(11):1788-1800. PubMed ID: 33188278
[TBL] [Abstract][Full Text] [Related]
16. Genetic variation in the alternative splicing regulator RBM20 is associated with dilated cardiomyopathy.
Refaat MM; Lubitz SA; Makino S; Islam Z; Frangiskakis JM; Mehdi H; Gutmann R; Zhang ML; Bloom HL; MacRae CA; Dudley SC; Shalaby AA; Weiss R; McNamara DM; London B; Ellinor PT
Heart Rhythm; 2012 Mar; 9(3):390-6. PubMed ID: 22004663
[TBL] [Abstract][Full Text] [Related]
17. Cardiomyopathy-associated mutations in the RS domain affect nuclear localization of RBM20.
Gaertner A; Klauke B; Felski E; Kassner A; Brodehl A; Gerdes D; Stanasiuk C; Ebbinghaus H; Schulz U; Dubowy KO; Tiesmeier J; Laser KT; Bante H; Bergau L; Sommer P; Fox H; Morshuis M; Gummert J; Milting H
Hum Mutat; 2020 Nov; 41(11):1931-1943. PubMed ID: 32840935
[TBL] [Abstract][Full Text] [Related]
18. Phosphorylation of the RSRSP stretch is critical for splicing regulation by RNA-Binding Motif Protein 20 (RBM20) through nuclear localization.
Murayama R; Kimura-Asami M; Togo-Ohno M; Yamasaki-Kato Y; Naruse TK; Yamamoto T; Hayashi T; Ai T; Spoonamore KG; Kovacs RJ; Vatta M; Iizuka M; Saito M; Wani S; Hiraoka Y; Kimura A; Kuroyanagi H
Sci Rep; 2018 Jun; 8(1):8970. PubMed ID: 29895960
[TBL] [Abstract][Full Text] [Related]
19. Mechanisms of RBM20 Cardiomyopathy: Insights From Model Systems.
Gregorich ZR; Zhang Y; Kamp TJ; Granzier HL; Guo W
Circ Genom Precis Med; 2024 Feb; 17(1):e004355. PubMed ID: 38288598
[TBL] [Abstract][Full Text] [Related]
20. Mutations in ribonucleic acid binding protein gene cause familial dilated cardiomyopathy.
Brauch KM; Karst ML; Herron KJ; de Andrade M; Pellikka PA; Rodeheffer RJ; Michels VV; Olson TM
J Am Coll Cardiol; 2009 Sep; 54(10):930-41. PubMed ID: 19712804
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]