194 related articles for article (PubMed ID: 34734468)
21. ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex.
Lee JH; Paull TT
Science; 2005 Apr; 308(5721):551-4. PubMed ID: 15790808
[TBL] [Abstract][Full Text] [Related]
22. Stable maintenance of the Mre11-Rad50-Nbs1 complex is sufficient to restore the DNA double-strand break response in cells lacking RecQL4 helicase activity.
Kim H; Choi H; Im JS; Park SY; Shin G; Yoo JH; Kim G; Lee JK
J Biol Chem; 2021 Oct; 297(4):101148. PubMed ID: 34473993
[TBL] [Abstract][Full Text] [Related]
23. miR-130a upregulates mTOR pathway by targeting TSC1 and is transactivated by NF-κB in high-grade serous ovarian carcinoma.
Wang Y; Zhang X; Tang W; Lin Z; Xu L; Dong R; Li Y; Li J; Zhang Z; Li X; Zhao L; Wei JJ; Shao C; Kong B; Liu Z
Cell Death Differ; 2017 Dec; 24(12):2089-2100. PubMed ID: 28800130
[TBL] [Abstract][Full Text] [Related]
24. ATM and the Mre11-Rad50-Nbs1 complex respond to nucleoside analogue-induced stalled replication forks and contribute to drug resistance.
Ewald B; Sampath D; Plunkett W
Cancer Res; 2008 Oct; 68(19):7947-55. PubMed ID: 18829552
[TBL] [Abstract][Full Text] [Related]
25. Functional characterization connects individual patient mutations in ataxia telangiectasia mutated (ATM) with dysfunction of specific DNA double-strand break-repair signaling pathways.
Keimling M; Volcic M; Csernok A; Wieland B; Dörk T; Wiesmüller L
FASEB J; 2011 Nov; 25(11):3849-60. PubMed ID: 21778326
[TBL] [Abstract][Full Text] [Related]
26. DNA-dependent protein kinase regulates DNA end resection in concert with Mre11-Rad50-Nbs1 (MRN) and ataxia telangiectasia-mutated (ATM).
Zhou Y; Paull TT
J Biol Chem; 2013 Dec; 288(52):37112-25. PubMed ID: 24220101
[TBL] [Abstract][Full Text] [Related]
27. ATM-mediated DNA double-strand break response facilitated oncolytic Newcastle disease virus replication and promoted syncytium formation in tumor cells.
Ren S; Ur Rehman Z; Gao B; Yang Z; Zhou J; Meng C; Song C; Nair V; Sun Y; Ding C
PLoS Pathog; 2020 Jun; 16(6):e1008514. PubMed ID: 32479542
[TBL] [Abstract][Full Text] [Related]
28. Multiple functions of MRN in end-joining pathways during isotype class switching.
Dinkelmann M; Spehalski E; Stoneham T; Buis J; Wu Y; Sekiguchi JM; Ferguson DO
Nat Struct Mol Biol; 2009 Aug; 16(8):808-13. PubMed ID: 19633670
[TBL] [Abstract][Full Text] [Related]
29. A mutant allele of MRE11 found in mismatch repair-deficient tumor cells suppresses the cellular response to DNA replication fork stress in a dominant negative manner.
Wen Q; Scorah J; Phear G; Rodgers G; Rodgers S; Meuth M
Mol Biol Cell; 2008 Apr; 19(4):1693-705. PubMed ID: 18256278
[TBL] [Abstract][Full Text] [Related]
30. Human RAD50 deficiency: Confirmation of a distinctive phenotype.
Ragamin A; Yigit G; Bousset K; Beleggia F; Verheijen FW; de Wit MY; Strom TM; Dörk T; Wollnik B; Mancini GMS
Am J Med Genet A; 2020 Jun; 182(6):1378-1386. PubMed ID: 32212377
[TBL] [Abstract][Full Text] [Related]
31. Human RAD50 deficiency in a Nijmegen breakage syndrome-like disorder.
Waltes R; Kalb R; Gatei M; Kijas AW; Stumm M; Sobeck A; Wieland B; Varon R; Lerenthal Y; Lavin MF; Schindler D; Dörk T
Am J Hum Genet; 2009 May; 84(5):605-16. PubMed ID: 19409520
[TBL] [Abstract][Full Text] [Related]
32. Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair.
Limbo O; Moiani D; Kertokalio A; Wyman C; Tainer JA; Russell P
Nucleic Acids Res; 2012 Dec; 40(22):11435-49. PubMed ID: 23080121
[TBL] [Abstract][Full Text] [Related]
33. The Rad50S allele promotes ATM-dependent DNA damage responses and suppresses ATM deficiency: implications for the Mre11 complex as a DNA damage sensor.
Morales M; Theunissen JW; Kim CF; Kitagawa R; Kastan MB; Petrini JH
Genes Dev; 2005 Dec; 19(24):3043-54. PubMed ID: 16357220
[TBL] [Abstract][Full Text] [Related]
34. L1CAM regulates DNA damage checkpoint response of glioblastoma stem cells through NBS1.
Cheng L; Wu Q; Huang Z; Guryanova OA; Huang Q; Shou W; Rich JN; Bao S
EMBO J; 2011 Mar; 30(5):800-13. PubMed ID: 21297581
[TBL] [Abstract][Full Text] [Related]
35. MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks.
Helmink BA; Bredemeyer AL; Lee BS; Huang CY; Sharma GG; Walker LM; Bednarski JJ; Lee WL; Pandita TK; Bassing CH; Sleckman BP
J Exp Med; 2009 Mar; 206(3):669-79. PubMed ID: 19221393
[TBL] [Abstract][Full Text] [Related]
36. Rad17 recruits the MRE11-RAD50-NBS1 complex to regulate the cellular response to DNA double-strand breaks.
Wang Q; Goldstein M; Alexander P; Wakeman TP; Sun T; Feng J; Lou Z; Kastan MB; Wang XF
EMBO J; 2014 Apr; 33(8):862-77. PubMed ID: 24534091
[TBL] [Abstract][Full Text] [Related]
37. Mre11-Rad50-Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity.
Jazayeri A; Balestrini A; Garner E; Haber JE; Costanzo V
EMBO J; 2008 Jul; 27(14):1953-62. PubMed ID: 18596698
[TBL] [Abstract][Full Text] [Related]
38. Persistence of unrepaired DNA double strand breaks caused by inhibition of ATM does not lead to radio-sensitisation in the absence of NF-κB activation.
Veuger SJ; Durkacz BW
DNA Repair (Amst); 2011 Feb; 10(2):235-44. PubMed ID: 21144805
[TBL] [Abstract][Full Text] [Related]
39. The Mre11-Rad50-Nbs1 complex acts both upstream and downstream of ataxia telangiectasia mutated and Rad3-related protein (ATR) to regulate the S-phase checkpoint following UV treatment.
Olson E; Nievera CJ; Lee AY; Chen L; Wu X
J Biol Chem; 2007 Aug; 282(31):22939-52. PubMed ID: 17526493
[TBL] [Abstract][Full Text] [Related]
40. Cleavage of the BRCT tandem domains of nibrin by the 657del5 mutation affects the DNA damage response less than the Arg215Trp mutation.
Mendez G; Cilli D; Berardinelli F; Viganotti M; Ascenzi P; Tanzarella C; Antoccia A; di Masi A
IUBMB Life; 2012 Oct; 64(10):853-61. PubMed ID: 22941933
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
