BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

302 related articles for article (PubMed ID: 34737701)

  • 1. Therapeutic Potential of SphK1 Inhibitors Based on Abnormal Expression of SphK1 in Inflammatory Immune Related-Diseases.
    Bu Y; Wu H; Deng R; Wang Y
    Front Pharmacol; 2021; 12():733387. PubMed ID: 34737701
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ginsenoside compound K inhibits angiogenesis via regulation of sphingosine kinase-1 in human umbilical vein endothelial cells.
    Shin KO; Seo CH; Cho HH; Oh S; Hong SP; Yoo HS; Hong JT; Oh KW; Lee YM
    Arch Pharm Res; 2014; 37(9):1183-92. PubMed ID: 24687256
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sphingosine kinase 1/sphingosine 1-phosphate/sphingosine 1-phosphate receptor 1 pathway: A novel target of geniposide to inhibit angiogenesis.
    Sun M; Deng R; Wang Y; Wu H; Zhang Z; Bu Y; Zhang H
    Life Sci; 2020 Sep; 256():117988. PubMed ID: 32569777
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Reduced sphingosine kinase-1 and enhanced sphingosine 1-phosphate lyase expression demonstrate deregulated sphingosine 1-phosphate signaling in Alzheimer's disease.
    Ceccom J; Loukh N; Lauwers-Cances V; Touriol C; Nicaise Y; Gentil C; Uro-Coste E; Pitson S; Maurage CA; Duyckaerts C; Cuvillier O; Delisle MB
    Acta Neuropathol Commun; 2014 Jan; 2():12. PubMed ID: 24468113
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Sphingosine kinase type 1 inhibition reveals rapid turnover of circulating sphingosine 1-phosphate.
    Kharel Y; Mathews TP; Gellett AM; Tomsig JL; Kennedy PC; Moyer ML; Macdonald TL; Lynch KR
    Biochem J; 2011 Dec; 440(3):345-53. PubMed ID: 21848514
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The sphingosine kinase 1/sphingosine-1-phosphate pathway in pulmonary arterial hypertension.
    Chen J; Tang H; Sysol JR; Moreno-Vinasco L; Shioura KM; Chen T; Gorshkova I; Wang L; Huang LS; Usatyuk PV; Sammani S; Zhou G; Raj JU; Garcia JG; Berdyshev E; Yuan JX; Natarajan V; Machado RF
    Am J Respir Crit Care Med; 2014 Nov; 190(9):1032-43. PubMed ID: 25180446
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hispidulin suppresses tumor growth and metastasis in renal cell carcinoma by modulating ceramide-sphingosine 1-phosphate rheostat.
    Gao MQ; Gao H; Han M; Liu KL; Peng JJ; Han YT
    Am J Cancer Res; 2017; 7(7):1501-1514. PubMed ID: 28744400
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Sphingosine kinase-1 mediates TNF-alpha-induced MCP-1 gene expression in endothelial cells: upregulation by oscillatory flow.
    Chen XL; Grey JY; Thomas S; Qiu FH; Medford RM; Wasserman MA; Kunsch C
    Am J Physiol Heart Circ Physiol; 2004 Oct; 287(4):H1452-8. PubMed ID: 15191888
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Factor-Xa-induced mitogenesis and migration require sphingosine kinase activity and S1P formation in human vascular smooth muscle cells.
    Böhm A; Flößer A; Ermler S; Fender AC; Lüth A; Kleuser B; Schrör K; Rauch BH
    Cardiovasc Res; 2013 Aug; 99(3):505-13. PubMed ID: 23658376
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Sphingosine kinase 1 in viral infections.
    Carr JM; Mahalingam S; Bonder CS; Pitson SM
    Rev Med Virol; 2013 Mar; 23(2):73-84. PubMed ID: 22639116
    [TBL] [Abstract][Full Text] [Related]  

  • 11. AP-1 regulates sphingosine kinase 1 expression in a positive feedback manner in glomerular mesangial cells exposed to high glucose.
    Huang K; Huang J; Chen C; Hao J; Wang S; Huang J; Liu P; Huang H
    Cell Signal; 2014 Mar; 26(3):629-38. PubMed ID: 24342046
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Sphingosine kinase 1/sphingosine-1-phosphate regulates the expression of interleukin-17A in activated microglia in cerebral ischemia/reperfusion.
    Lv M; Zhang D; Dai D; Zhang W; Zhang L
    Inflamm Res; 2016 Jul; 65(7):551-62. PubMed ID: 27002656
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Neuroprotective role of sphingolipid rheostat in excitotoxic retinal ganglion cell death.
    Nakamura N; Honjo M; Yamagishi R; Kurano M; Yatomi Y; Watanabe S; Aihara M
    Exp Eye Res; 2021 Jul; 208():108623. PubMed ID: 34022173
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Geniposide downregulates the VEGF/SphK1/S1P pathway and alleviates angiogenesis in rheumatoid arthritis in vivo and in vitro.
    Wang Y; Wu H; Deng R; Dai XJ; Bu YH; Sun MH; Zhang H; Wang MD; Wang RH
    Phytother Res; 2021 Aug; 35(8):4347-4362. PubMed ID: 34152633
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Sphingosine kinase and sphingosine-1-phosphate receptor signaling pathway in inflammatory gastrointestinal disease and cancers: A novel therapeutic target.
    Sukocheva OA; Furuya H; Ng ML; Friedemann M; Menschikowski M; Tarasov VV; Chubarev VN; Klochkov SG; Neganova ME; Mangoni AA; Aliev G; Bishayee A
    Pharmacol Ther; 2020 Mar; 207():107464. PubMed ID: 31863815
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Sphingosine kinase 1 (SPHK1) is induced by transforming growth factor-beta and mediates TIMP-1 up-regulation.
    Yamanaka M; Shegogue D; Pei H; Bu S; Bielawska A; Bielawski J; Pettus B; Hannun YA; Obeid L; Trojanowska M
    J Biol Chem; 2004 Dec; 279(52):53994-4001. PubMed ID: 15485866
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sphingolipids as mediators of inflammation and novel therapeutic target in inflammatory bowel disease.
    Sukocheva OA; Lukina E; McGowan E; Bishayee A
    Adv Protein Chem Struct Biol; 2020; 120():123-158. PubMed ID: 32085881
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Modulation of cellular S1P levels with a novel, potent and specific inhibitor of sphingosine kinase-1.
    Schnute ME; McReynolds MD; Kasten T; Yates M; Jerome G; Rains JW; Hall T; Chrencik J; Kraus M; Cronin CN; Saabye M; Highkin MK; Broadus R; Ogawa S; Cukyne K; Zawadzke LE; Peterkin V; Iyanar K; Scholten JA; Wendling J; Fujiwara H; Nemirovskiy O; Wittwer AJ; Nagiec MM
    Biochem J; 2012 May; 444(1):79-88. PubMed ID: 22397330
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sphingosine kinase 1 and sphingosine 1-phosphate receptor 3 are functionally upregulated on astrocytes under pro-inflammatory conditions.
    Fischer I; Alliod C; Martinier N; Newcombe J; Brana C; Pouly S
    PLoS One; 2011; 6(8):e23905. PubMed ID: 21887342
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Activation-Induced Cell Death of Dendritic Cells Is Dependent on Sphingosine Kinase 1.
    Schwiebs A; Friesen O; Katzy E; Ferreirós N; Pfeilschifter JM; Radeke HH
    Front Pharmacol; 2016; 7():94. PubMed ID: 27148053
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.