BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

187 related articles for article (PubMed ID: 34740687)

  • 1. A review on the emerging roles of pyruvate kinase M2 in anti-leukemia therapy.
    Yang GJ; Wu J; Leung CH; Ma DL; Chen J
    Int J Biol Macromol; 2021 Dec; 193(Pt B):1499-1506. PubMed ID: 34740687
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Apigenin Restrains Colon Cancer Cell Proliferation via Targeted Blocking of Pyruvate Kinase M2-Dependent Glycolysis.
    Shan S; Shi J; Yang P; Jia B; Wu H; Zhang X; Li Z
    J Agric Food Chem; 2017 Sep; 65(37):8136-8144. PubMed ID: 28829588
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pyruvate kinase M2: multiple faces for conferring benefits on cancer cells.
    Tamada M; Suematsu M; Saya H
    Clin Cancer Res; 2012 Oct; 18(20):5554-61. PubMed ID: 23071357
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Resveratrol inhibits cancer cell metabolism by down regulating pyruvate kinase M2 via inhibition of mammalian target of rapamycin.
    Iqbal MA; Bamezai RN
    PLoS One; 2012; 7(5):e36764. PubMed ID: 22574221
    [TBL] [Abstract][Full Text] [Related]  

  • 5. N6-isopentenyladenosine inhibits aerobic glycolysis in glioblastoma cells by targeting PKM2 expression and activity.
    Pagano C; Coppola L; Navarra G; Avilia G; Savarese B; Torelli G; Bruzzaniti S; Piemonte E; Galgani M; Laezza C; Bifulco M
    FEBS Open Bio; 2024 May; 14(5):843-854. PubMed ID: 38514913
    [TBL] [Abstract][Full Text] [Related]  

  • 6. SUMOylation disassembles the tetrameric pyruvate kinase M2 to block myeloid differentiation of leukemia cells.
    Xia L; Jiang Y; Zhang XH; Wang XR; Wei R; Qin K; Lu Y
    Cell Death Dis; 2021 Jan; 12(1):101. PubMed ID: 33473116
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A short review on cross-link between pyruvate kinase (PKM2) and Glioblastoma Multiforme.
    Verma H; Cholia RP; Kaur S; Dhiman M; Mantha AK
    Metab Brain Dis; 2021 Jun; 36(5):751-765. PubMed ID: 33651273
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of Natural Compounds as Inhibitors of Pyruvate Kinase M2 for Cancer Treatment.
    Sarfraz I; Rasul A; Jabeen F; Sultana T; Adem Ş
    Molecules; 2022 Oct; 27(20):. PubMed ID: 36296707
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth.
    Sun Q; Chen X; Ma J; Peng H; Wang F; Zha X; Wang Y; Jing Y; Yang H; Chen R; Chang L; Zhang Y; Goto J; Onda H; Chen T; Wang MR; Lu Y; You H; Kwiatkowski D; Zhang H
    Proc Natl Acad Sci U S A; 2011 Mar; 108(10):4129-34. PubMed ID: 21325052
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Aurora A-mediated pyruvate kinase M2 phosphorylation promotes biosynthesis with glycolytic metabolites and tumor cell cycle progression.
    Jiang Y; Wang T; Sheng D; Han C; Xu T; Zhang P; You W; Fan W; Zhang Z; Jin T; Duan X; Yuan X; Liu X; Zhang K; Ruan K; Shi J; Guo J; Cheng A; Yang Z
    J Biol Chem; 2022 Nov; 298(11):102561. PubMed ID: 36198360
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Beta-elemene inhibits breast cancer metastasis through blocking pyruvate kinase M2 dimerization and nuclear translocation.
    Pan Y; Wang W; Huang S; Ni W; Wei Z; Cao Y; Yu S; Jia Q; Wu Y; Chai C; Zheng Q; Zhang L; Wang A; Sun Z; Huang S; Wang S; Chen W; Lu Y
    J Cell Mol Med; 2019 Oct; 23(10):6846-6858. PubMed ID: 31343107
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cancer metabolism control by natural products: Pyruvate kinase M2 targeting therapeutics.
    El-Far AH; Al Jaouni SK; Li X; Fu J
    Phytother Res; 2022 Aug; 36(8):3181-3201. PubMed ID: 35794729
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pyruvate kinase: Function, regulation and role in cancer.
    Israelsen WJ; Vander Heiden MG
    Semin Cell Dev Biol; 2015 Jul; 43():43-51. PubMed ID: 26277545
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Discovery and structure-guided fragment-linking of 4-(2,3-dichlorobenzoyl)-1-methyl-pyrrole-2-carboxamide as a pyruvate kinase M2 activator.
    Matsui Y; Yasumatsu I; Asahi T; Kitamura T; Kanai K; Ubukata O; Hayasaka H; Takaishi S; Hanzawa H; Katakura S
    Bioorg Med Chem; 2017 Jul; 25(13):3540-3546. PubMed ID: 28511909
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pyruvate kinase M2 contributes to cell growth in gastric cancer via aerobic glycolysis.
    Li H; Xu H; Xing R; Pan Y; Li W; Cui J; Lu Y
    Pathol Res Pract; 2019 Jun; 215(6):152409. PubMed ID: 31000383
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Evaluation of Glycolytic Response to Multiple Classes of Anti-glioblastoma Drugs by Noninvasive Measurement of Pyruvate Kinase M2 Using [
    Beinat C; Patel CB; Xie Y; Gambhir SS
    Mol Imaging Biol; 2020 Feb; 22(1):124-133. PubMed ID: 30989436
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Lapachol inhibits glycolysis in cancer cells by targeting pyruvate kinase M2.
    Shankar Babu M; Mahanta S; Lakhter AJ; Hato T; Paul S; Naidu SR
    PLoS One; 2018; 13(2):e0191419. PubMed ID: 29394289
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Shikonin and its analogs inhibit cancer cell glycolysis by targeting tumor pyruvate kinase-M2.
    Chen J; Xie J; Jiang Z; Wang B; Wang Y; Hu X
    Oncogene; 2011 Oct; 30(42):4297-306. PubMed ID: 21516121
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Evidence That Does Not Support Pyruvate Kinase M2 (PKM2)-catalyzed Reaction as a Rate-limiting Step in Cancer Cell Glycolysis.
    Xie J; Dai C; Hu X
    J Biol Chem; 2016 Apr; 291(17):8987-99. PubMed ID: 26917721
    [TBL] [Abstract][Full Text] [Related]  

  • 20. p,p'-Dichlorodiphenyltrichloroethane promotes aerobic glycolysis via reactive oxygen species-mediated extracellular signal-regulated kinase/M2 isoform of pyruvate kinase (PKM2) signaling in colorectal cancer cells.
    Song L; Dong N; Li Z
    Environ Toxicol; 2020 Mar; 35(3):333-345. PubMed ID: 31724279
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.