187 related articles for article (PubMed ID: 34747365)
1. SPINK1 as a plasma marker for tumor hypoxia and a therapeutic target for radiosensitization.
Suwa T; Kobayashi M; Shirai Y; Nam JM; Tabuchi Y; Takeda N; Akamatsu S; Ogawa O; Mizowaki T; Hammond EM; Harada H
JCI Insight; 2021 Nov; 6(21):. PubMed ID: 34747365
[TBL] [Abstract][Full Text] [Related]
2. Serine Protease Inhibitor Kazal Type 1, A Potential Biomarker for the Early Detection, Targeting, and Prediction of Response to Immune Checkpoint Blockade Therapies in Hepatocellular Carcinoma.
Jia J; Ga L; Liu Y; Yang Z; Wang Y; Guo X; Ma R; Liu R; Li T; Tang Z; Wang J
Front Immunol; 2022; 13():923031. PubMed ID: 35924241
[TBL] [Abstract][Full Text] [Related]
3. Targeting SPINK1 in the damaged tumour microenvironment alleviates therapeutic resistance.
Chen F; Long Q; Fu D; Zhu D; Ji Y; Han L; Zhang B; Xu Q; Liu B; Li Y; Wu S; Yang C; Qian M; Xu J; Liu S; Cao L; Chin YE; Lam EW; Coppé JP; Sun Y
Nat Commun; 2018 Oct; 9(1):4315. PubMed ID: 30333494
[TBL] [Abstract][Full Text] [Related]
4. MAPK inhibitors induce serine peptidase inhibitor Kazal type 1 (SPINK1) secretion in BRAF V600E-mutant colorectal adenocarcinoma.
Räsänen K; Dang KX; Mustonen H; Ho TH; Lintula S; Koistinen H; Stenman UH; Haglund C; Stenman J
Mol Oncol; 2018 Feb; 12(2):224-238. PubMed ID: 29193645
[TBL] [Abstract][Full Text] [Related]
5. Serine protease inhibitor Kazal type 1 (SPINK1) promotes proliferation, migration, invasion and radiation resistance in rectal cancer patients receiving concurrent chemoradiotherapy: a potential target for precision medicine.
Chen YT; Tseng TT; Tsai HP; Kuo SH; Huang MY; Wang JY; Chai CY
Hum Cell; 2022 Nov; 35(6):1912-1927. PubMed ID: 36053457
[TBL] [Abstract][Full Text] [Related]
6. Functional Roles of SPINK1 in Cancers.
Lin TC
Int J Mol Sci; 2021 Apr; 22(8):. PubMed ID: 33916984
[TBL] [Abstract][Full Text] [Related]
7. Hepatitis B Virus X Protein-Induced Serine Protease Inhibitor Kazal Type 1 Is Associated with the Progression of HBV-Related Diseases.
Zhu C; Han H; Li J; Xu L; Liu F; Wu K; Liu X
Biomed Res Int; 2019; 2019():9321494. PubMed ID: 31240230
[TBL] [Abstract][Full Text] [Related]
8. Interleukin-6 increases expression of serine protease inhibitor Kazal type 1 through STAT3 in colorectal adenocarcinoma.
Räsänen K; Lehtinen E; Nokelainen K; Kuopio T; Hautala L; Itkonen O; Stenman UH; Koistinen H
Mol Carcinog; 2016 Dec; 55(12):2010-2023. PubMed ID: 26663388
[TBL] [Abstract][Full Text] [Related]
9. Therapeutic targeting of SPINK1-positive prostate cancer.
Ateeq B; Tomlins SA; Laxman B; Asangani IA; Cao Q; Cao X; Li Y; Wang X; Feng FY; Pienta KJ; Varambally S; Chinnaiyan AM
Sci Transl Med; 2011 Mar; 3(72):72ra17. PubMed ID: 21368222
[TBL] [Abstract][Full Text] [Related]
10. Defective binding of SPINK1 variants is an uncommon mechanism for impaired trypsin inhibition in chronic pancreatitis.
Szabó A; Toldi V; Gazda LD; Demcsák A; Tőzsér J; Sahin-Tóth M
J Biol Chem; 2021; 296():100343. PubMed ID: 33515547
[TBL] [Abstract][Full Text] [Related]
11. Roles of serine protease inhibitor Kazal type 1 (SPINK1) in pancreatic diseases.
Ohmuraya M; Yamamura K
Exp Anim; 2011; 60(5):433-44. PubMed ID: 22041280
[TBL] [Abstract][Full Text] [Related]
12. Identification and Exploration of Serine Peptidase Inhibitor Kazal Type I (SPINK1) as a Potential Biomarker Correlated with the Progression of Non-Small Cell Lung Cancer.
Li D; Zhang X; Ding Z; Ai R; Shi L; Wang Z; He Q; Dong Y; Zhu Y; Ouyang W; He Y
Cell Biochem Biophys; 2022 Dec; 80(4):807-818. PubMed ID: 36194314
[TBL] [Abstract][Full Text] [Related]
13. Emerging Roles of SPINK1 in Cancer.
Räsänen K; Itkonen O; Koistinen H; Stenman UH
Clin Chem; 2016 Mar; 62(3):449-57. PubMed ID: 26656134
[TBL] [Abstract][Full Text] [Related]
14. Polyoxometalate-Based Radiosensitization Platform for Treating Hypoxic Tumors by Attenuating Radioresistance and Enhancing Radiation Response.
Yong Y; Zhang C; Gu Z; Du J; Guo Z; Dong X; Xie J; Zhang G; Liu X; Zhao Y
ACS Nano; 2017 Jul; 11(7):7164-7176. PubMed ID: 28640996
[TBL] [Abstract][Full Text] [Related]
15. The impact of physiological stress conditions on protein structure and trypsin inhibition of serine protease inhibitor Kazal type 1 (SPINK1) and its N34S variant.
Buchholz I; Nagel F; Klein A; Wagh PR; Mahajan UM; Greinacher A; Lerch MM; Mayerle J; Delcea M
Biochim Biophys Acta Proteins Proteom; 2020 Jan; 1868(1):140281. PubMed ID: 31525466
[TBL] [Abstract][Full Text] [Related]
16. SPINK1-induced tumor plasticity provides a therapeutic window for chemotherapy in hepatocellular carcinoma.
Man KF; Zhou L; Yu H; Lam KH; Cheng W; Yu J; Lee TK; Yun JP; Guan XY; Liu M; Ma S
Nat Commun; 2023 Nov; 14(1):7863. PubMed ID: 38030644
[TBL] [Abstract][Full Text] [Related]
17. Serine peptidase inhibitor Kazal type 1 (SPINK1) as novel downstream effector of the cadherin-17/β-catenin axis in hepatocellular carcinoma.
Shek FH; Luo R; Lam BYH; Sung WK; Lam TW; Luk JM; Leung MS; Chan KT; Wang HK; Chan CM; Poon RT; Lee NP
Cell Oncol (Dordr); 2017 Oct; 40(5):443-456. PubMed ID: 28631187
[TBL] [Abstract][Full Text] [Related]
18. Small interfering RNA targeting HIF-1α reduces hypoxia-dependent transcription and radiosensitizes hypoxic HT 1080 human fibrosarcoma cells in vitro.
Staab A; Fleischer M; Loeffler J; Said HM; Katzer A; Plathow C; Einsele H; Flentje M; Vordermark D
Strahlenther Onkol; 2011 Apr; 187(4):252-9. PubMed ID: 21437769
[TBL] [Abstract][Full Text] [Related]
19. Effect of low dose of berberine on the radioresistance of cervical cancer cells via a PI3K/HIF-1 pathway under nutrient-deprived conditions.
Zeng X; Wan L; Wang Y; Xue J; Yang H; Zhu Y
Int J Radiat Biol; 2020 Aug; 96(8):1060-1067. PubMed ID: 32412317
[No Abstract] [Full Text] [Related]
20. miR-421 up-regulation by the oleanolic acid derivative K73-03 regulates epigenetically SPINK1 transcription in pancreatic cancer cells leading to metabolic changes and enhanced apoptosis.
Shopit A; Li X; Tang Z; Awsh M; Shobet L; Niu M; Wang H; Mousa H; Alshwmi M; Tesfaldet T; Gamallat Y; Li H; Chu P; Ahmad N; Jamalat Y; Ai J; Qaed E; Almoiliqy M; Wang S; Tang Z
Pharmacol Res; 2020 Nov; 161():105130. PubMed ID: 32818653
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]