BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

224 related articles for article (PubMed ID: 34749650)

  • 1. Dimethyl itaconate alleviates the pyroptosis of macrophages through oxidative stress.
    Huang SS; Guo DY; Jia BB; Cai GL; Yan J; Lu Y; Yang ZX
    BMC Immunol; 2021 Nov; 22(1):72. PubMed ID: 34749650
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dimethyl itaconate inhibits LPS‑induced microglia inflammation and inflammasome‑mediated pyroptosis via inducing autophagy and regulating the Nrf‑2/HO‑1 signaling pathway.
    Yang S; Zhang X; Zhang H; Lin X; Chen X; Zhang Y; Lin X; Huang L; Zhuge Q
    Mol Med Rep; 2021 Sep; 24(3):. PubMed ID: 34296312
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dimethyl Itaconate Alleviates the Inflammatory Responses of Macrophages in Sepsis.
    Zhang S; Jiao Y; Li C; Liang X; Jia H; Nie Z; Zhang Y
    Inflammation; 2021 Apr; 44(2):549-557. PubMed ID: 33029757
    [TBL] [Abstract][Full Text] [Related]  

  • 4. IRG1/itaconate alleviates acute liver injury in septic mice by suppressing NLRP3 expression and its mediated macrophage pyroptosis via regulation of the Nrf2 pathway.
    Zhou P; Yang L; Li R; Yin Y; Xie G; Liu X; Shi L; Tao K; Zhang P
    Int Immunopharmacol; 2024 Jun; 135():112277. PubMed ID: 38788445
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dimethyl itaconate protects against lippolysacchride-induced mastitis in mice by activating MAPKs and Nrf2 and inhibiting NF-κB signaling pathways.
    Zhao C; Jiang P; He Z; Yuan X; Guo J; Li Y; Hu X; Cao Y; Fu Y; Zhang N
    Microb Pathog; 2019 Aug; 133():103541. PubMed ID: 31100405
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 4-Octyl Itaconate Activates Nrf2 Signaling to Inhibit Pro-Inflammatory Cytokine Production in Peripheral Blood Mononuclear Cells of Systemic Lupus Erythematosus Patients.
    Tang C; Wang X; Xie Y; Cai X; Yu N; Hu Y; Zheng Z
    Cell Physiol Biochem; 2018; 51(2):979-990. PubMed ID: 30466076
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Immune Response Gene-1 [IRG1]/itaconate protect against multi-organ injury via inhibiting gasdermin D-mediated pyroptosis and inflammatory response.
    Yang W; Wang Y; Huang Y; Wang T; Li C; Zhang P; Liu W; Yin Y; Li R; Tao K
    Inflammopharmacology; 2024 Feb; 32(1):419-432. PubMed ID: 37470905
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Maresin 1 protects against lipopolysaccharide/d-galactosamine-induced acute liver injury by inhibiting macrophage pyroptosis and inflammatory response.
    Yang W; Tao K; Zhang P; Chen X; Sun X; Li R
    Biochem Pharmacol; 2022 Jan; 195():114863. PubMed ID: 34861244
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Electrophilic properties of itaconate and derivatives regulate the IκBζ-ATF3 inflammatory axis.
    Bambouskova M; Gorvel L; Lampropoulou V; Sergushichev A; Loginicheva E; Johnson K; Korenfeld D; Mathyer ME; Kim H; Huang LH; Duncan D; Bregman H; Keskin A; Santeford A; Apte RS; Sehgal R; Johnson B; Amarasinghe GK; Soares MP; Satoh T; Akira S; Hai T; de Guzman Strong C; Auclair K; Roddy TP; Biller SA; Jovanovic M; Klechevsky E; Stewart KM; Randolph GJ; Artyomov MN
    Nature; 2018 Apr; 556(7702):501-504. PubMed ID: 29670287
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Itaconate confers tolerance to late NLRP3 inflammasome activation.
    Bambouskova M; Potuckova L; Paulenda T; Kerndl M; Mogilenko DA; Lizotte K; Swain A; Hayes S; Sheldon RD; Kim H; Kapadnis U; Ellis AE; Isaguirre C; Burdess S; Laha A; Amarasinghe GK; Chubukov V; Roddy TP; Diamond MS; Jones RG; Simons DM; Artyomov MN
    Cell Rep; 2021 Mar; 34(10):108756. PubMed ID: 33691097
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The Immunomodulatory Potential of the Metabolite Itaconate.
    Hooftman A; O'Neill LAJ
    Trends Immunol; 2019 Aug; 40(8):687-698. PubMed ID: 31178405
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The anti-inflammatory drug dimethyl itaconate protects against colitis-associated colorectal cancer.
    Wang Q; Li XL; Mei Y; Ye JC; Fan W; Cheng GH; Zeng MS; Feng GK
    J Mol Med (Berl); 2020 Oct; 98(10):1457-1466. PubMed ID: 32840638
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Alliin alleviates LPS-induced pyroptosis via promoting mitophagy in THP-1 macrophages and mice.
    Liu M; Lu J; Yang S; Chen Y; Yu J; Guan S
    Food Chem Toxicol; 2022 Feb; 160():112811. PubMed ID: 34999177
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Investigating the role of itaconate in macrophage activation and oxidative stress injury in sepsis-associated acute kidney injury.
    Yang L; Zhou P; Li R; Yin Y; Xie G; Shi L; Zhang P; Tao K
    Mol Biol Rep; 2024 Apr; 51(1):533. PubMed ID: 38642169
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 6-Gingerol attenuates macrophages pyroptosis via the inhibition of MAPK signaling pathways and predicts a good prognosis in sepsis.
    Zhang FL; Zhou BW; Yan ZZ; Zhao J; Zhao BC; Liu WF; Li C; Liu KX
    Cytokine; 2020 Jan; 125():154854. PubMed ID: 31539844
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dimethyl itaconate protects against fungal keratitis by activating the Nrf2/HO-1 signaling pathway.
    Gu L; Lin J; Wang Q; Li C; Peng X; Fan Y; Lu C; Lin H; Niu Y; Zhu G; Zhao G
    Immunol Cell Biol; 2020 Mar; 98(3):229-241. PubMed ID: 31943336
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hypoxia-reoxygenation induces macrophage polarization and causes the release of exosomal miR-29a to mediate cardiomyocyte pyroptosis.
    Wang Y; Qiu Z; Yuan J; Li C; Zhao R; Liu W; Deng W; Gu N; Zhang W; Hu S; Bai Z; Shi B
    In Vitro Cell Dev Biol Anim; 2021 Jan; 57(1):30-41. PubMed ID: 33420578
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Gallic Acid Alleviates Gouty Arthritis by Inhibiting NLRP3 Inflammasome Activation and Pyroptosis Through Enhancing Nrf2 Signaling.
    Lin Y; Luo T; Weng A; Huang X; Yao Y; Fu Z; Li Y; Liu A; Li X; Chen D; Pan H
    Front Immunol; 2020; 11():580593. PubMed ID: 33365024
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dihydromyricetin inhibits NLRP3 inflammasome-dependent pyroptosis by activating the Nrf2 signaling pathway in vascular endothelial cells.
    Hu Q; Zhang T; Yi L; Zhou X; Mi M
    Biofactors; 2018 Mar; 44(2):123-136. PubMed ID: 29193391
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Electrophilic Nrf2 activators and itaconate inhibit inflammation at low dose and promote IL-1β production and inflammatory apoptosis at high dose.
    Muri J; Wolleb H; Broz P; Carreira EM; Kopf M
    Redox Biol; 2020 Sep; 36():101647. PubMed ID: 32863237
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.