BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

219 related articles for article (PubMed ID: 34757789)

  • 1. Frizzled BRET sensors based on bioorthogonal labeling of unnatural amino acids reveal WNT-induced dynamics of the cysteine-rich domain.
    Kowalski-Jahn M; Schihada H; Turku A; Huber T; Sakmar TP; Schulte G
    Sci Adv; 2021 Nov; 7(46):eabj7917. PubMed ID: 34757789
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Conformational GPCR BRET Sensors Based on Bioorthogonal Labeling of Noncanonical Amino Acids.
    Kowalski-Jahn M; Schihada H; Schulte G
    Methods Mol Biol; 2023; 2676():201-213. PubMed ID: 37277635
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Deconvolution of WNT-induced Frizzled conformational dynamics with fluorescent biosensors.
    Schihada H; Kowalski-Jahn M; Turku A; Schulte G
    Biosens Bioelectron; 2021 Apr; 177():112948. PubMed ID: 33486136
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Wnt5a promotes Frizzled-4 signalosome assembly by stabilizing cysteine-rich domain dimerization.
    DeBruine ZJ; Ke J; Harikumar KG; Gu X; Borowsky P; Williams BO; Xu W; Miller LJ; Xu HE; Melcher K
    Genes Dev; 2017 May; 31(9):916-926. PubMed ID: 28546512
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Quantitative Profiling of WNT-3A Binding to All Human Frizzled Paralogues in HEK293 Cells by NanoBiT/BRET Assessments.
    Kozielewicz P; Shekhani R; Moser S; Bowin CF; Wesslowski J; Davidson G; Schulte G
    ACS Pharmacol Transl Sci; 2021 Jun; 4(3):1235-1245. PubMed ID: 34151213
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Unsaturated fatty acyl recognition by Frizzled receptors mediates dimerization upon Wnt ligand binding.
    Nile AH; Mukund S; Stanger K; Wang W; Hannoush RN
    Proc Natl Acad Sci U S A; 2017 Apr; 114(16):4147-4152. PubMed ID: 28377511
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Functional dissection of the N-terminal extracellular domains of Frizzled 6 reveals their roles for receptor localization and Dishevelled recruitment.
    Valnohova J; Kowalski-Jahn M; Sunahara RK; Schulte G
    J Biol Chem; 2018 Nov; 293(46):17875-17887. PubMed ID: 30237173
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The evolutionary analysis reveals domain fusion of proteins with Frizzled-like CRD domain.
    Yan J; Jia H; Ma Z; Ye H; Zhou M; Su L; Liu J; Guo AY
    Gene; 2014 Jan; 533(1):229-39. PubMed ID: 24135643
    [TBL] [Abstract][Full Text] [Related]  

  • 9. WNT stimulation induces dynamic conformational changes in the Frizzled-Dishevelled interaction.
    Bowin CF; Kozielewicz P; Grätz L; Kowalski-Jahn M; Schihada H; Schulte G
    Sci Signal; 2023 Apr; 16(779):eabo4974. PubMed ID: 37014927
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Systematic mapping of WNT-FZD protein interactions reveals functional selectivity by distinct WNT-FZD pairs.
    Dijksterhuis JP; Baljinnyam B; Stanger K; Sercan HO; Ji Y; Andres O; Rubin JS; Hannoush RN; Schulte G
    J Biol Chem; 2015 Mar; 290(11):6789-98. PubMed ID: 25605717
    [TBL] [Abstract][Full Text] [Related]  

  • 11. eGFP-tagged Wnt-3a enables functional analysis of Wnt trafficking and signaling and kinetic assessment of Wnt binding to full-length Frizzled.
    Wesslowski J; Kozielewicz P; Wang X; Cui H; Schihada H; Kranz D; Karuna M P; Levkin P; Gross JC; Boutros M; Schulte G; Davidson G
    J Biol Chem; 2020 Jun; 295(26):8759-8774. PubMed ID: 32381507
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Secreted Frizzled-related protein potentiation versus inhibition of Wnt3a/β-catenin signaling.
    Xavier CP; Melikova M; Chuman Y; Üren A; Baljinnyam B; Rubin JS
    Cell Signal; 2014 Jan; 26(1):94-101. PubMed ID: 24080158
    [TBL] [Abstract][Full Text] [Related]  

  • 13. WNT-3A-induced β-catenin signaling does not require signaling through heterotrimeric G proteins.
    Bowin CF; Inoue A; Schulte G
    J Biol Chem; 2019 Aug; 294(31):11677-11684. PubMed ID: 31235524
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Wnt Binding Affinity Prediction for Putative Frizzled-Type Cysteine-Rich Domains.
    Agostino M; Pohl SÖ
    Int J Mol Sci; 2019 Aug; 20(17):. PubMed ID: 31454915
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Biophysical and functional characterization of Norrin signaling through Frizzled4.
    Bang I; Kim HR; Beaven AH; Kim J; Ko SB; Lee GR; Kan W; Lee H; Im W; Seok C; Chung KY; Choi HJ
    Proc Natl Acad Sci U S A; 2018 Aug; 115(35):8787-8792. PubMed ID: 30104375
    [TBL] [Abstract][Full Text] [Related]  

  • 16. WNT/Frizzled signalling: receptor-ligand selectivity with focus on FZD-G protein signalling and its physiological relevance: IUPHAR Review 3.
    Dijksterhuis JP; Petersen J; Schulte G
    Br J Pharmacol; 2014 Mar; 171(5):1195-209. PubMed ID: 24032637
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Frizzleds and WNT/β-catenin signaling--The black box of ligand-receptor selectivity, complex stoichiometry and activation kinetics.
    Schulte G
    Eur J Pharmacol; 2015 Sep; 763(Pt B):191-5. PubMed ID: 26003275
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Employing Genetically Encoded, Biophysical Sensors to Understand WNT/Frizzled Interaction and Receptor Complex Activation.
    Kozielewicz P; Schihada H; Schulte G
    Handb Exp Pharmacol; 2021; 269():101-115. PubMed ID: 34463848
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Frizzleds act as dynamic pharmacological entities.
    Schulte G; Scharf MM; Bous J; Voss JH; Grätz L; Kozielewicz P
    Trends Pharmacol Sci; 2024 May; 45(5):419-429. PubMed ID: 38594145
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Prediction of structure of human WNT-CRD (FZD) complex for computational drug repurposing.
    Ain QU; Seemab U; Rashid S; Nawaz MS; Kamal MA
    PLoS One; 2013; 8(1):e54630. PubMed ID: 23372744
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.