BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

168 related articles for article (PubMed ID: 34768779)

  • 1. Structural Analysis and Spatiotemporal Expression of
    Vauti F; Vögele V; Deppe I; Hahnenstein ST; Köster RW
    Int J Mol Sci; 2021 Oct; 22(21):. PubMed ID: 34768779
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization of the zebrafish atxn1/axh gene family.
    Carlson KM; Melcher L; Lai S; Zoghbi HY; Clark HB; Orr HT
    J Neurogenet; 2009; 23(3):313-23. PubMed ID: 19085187
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Partial loss of ataxin-1 function contributes to transcriptional dysregulation in spinocerebellar ataxia type 1 pathogenesis.
    Crespo-Barreto J; Fryer JD; Shaw CA; Orr HT; Zoghbi HY
    PLoS Genet; 2010 Jul; 6(7):e1001021. PubMed ID: 20628574
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Duplication of Atxn1l suppresses SCA1 neuropathology by decreasing incorporation of polyglutamine-expanded ataxin-1 into native complexes.
    Bowman AB; Lam YC; Jafar-Nejad P; Chen HK; Richman R; Samaco RC; Fryer JD; Kahle JJ; Orr HT; Zoghbi HY
    Nat Genet; 2007 Mar; 39(3):373-9. PubMed ID: 17322884
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Genetic Modeling of the Neurodegenerative Disease Spinocerebellar Ataxia Type 1 in Zebrafish.
    Elsaey MA; Namikawa K; Köster RW
    Int J Mol Sci; 2021 Jul; 22(14):. PubMed ID: 34298970
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ATXN1-CIC Complex Is the Primary Driver of Cerebellar Pathology in Spinocerebellar Ataxia Type 1 through a Gain-of-Function Mechanism.
    Rousseaux MWC; Tschumperlin T; Lu HC; Lackey EP; Bondar VV; Wan YW; Tan Q; Adamski CJ; Friedrich J; Twaroski K; Chen W; Tolar J; Henzler C; Sharma A; Bajić A; Lin T; Duvick L; Liu Z; Sillitoe RV; Zoghbi HY; Orr HT
    Neuron; 2018 Mar; 97(6):1235-1243.e5. PubMed ID: 29526553
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ataxin-1 regulates the cerebellar bioenergetics proteome through the GSK3β-mTOR pathway which is altered in Spinocerebellar ataxia type 1 (SCA1).
    Sánchez I; Balagué E; Matilla-Dueñas A
    Hum Mol Genet; 2016 Sep; 25(18):4021-4040. PubMed ID: 27466200
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cerebellar contribution to the cognitive alterations in SCA1: evidence from mouse models.
    Asher M; Rosa JG; Rainwater O; Duvick L; Bennyworth M; Lai RY; ; Kuo SH; Cvetanovic M
    Hum Mol Genet; 2020 Jan; 29(1):117-131. PubMed ID: 31696233
    [TBL] [Abstract][Full Text] [Related]  

  • 9. ATXN1 protein family and CIC regulate extracellular matrix remodeling and lung alveolarization.
    Lee Y; Fryer JD; Kang H; Crespo-Barreto J; Bowman AB; Gao Y; Kahle JJ; Hong JS; Kheradmand F; Orr HT; Finegold MJ; Zoghbi HY
    Dev Cell; 2011 Oct; 21(4):746-57. PubMed ID: 22014525
    [TBL] [Abstract][Full Text] [Related]  

  • 10. An out-of-frame overlapping reading frame in the ataxin-1 coding sequence encodes a novel ataxin-1 interacting protein.
    Bergeron D; Lapointe C; Bissonnette C; Tremblay G; Motard J; Roucou X
    J Biol Chem; 2013 Jul; 288(30):21824-35. PubMed ID: 23760502
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cerebellar Transcriptome Profiles of ATXN1 Transgenic Mice Reveal SCA1 Disease Progression and Protection Pathways.
    Ingram M; Wozniak EAL; Duvick L; Yang R; Bergmann P; Carson R; O'Callaghan B; Zoghbi HY; Henzler C; Orr HT
    Neuron; 2016 Mar; 89(6):1194-1207. PubMed ID: 26948890
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Functional implications of paralog genes in polyglutamine spinocerebellar ataxias.
    Felício D; du Mérac TR; Amorim A; Martins S
    Hum Genet; 2023 Dec; 142(12):1651-1676. PubMed ID: 37845370
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Decreasing mutant ATXN1 nuclear localization improves a spectrum of SCA1-like phenotypes and brain region transcriptomic profiles.
    Handler HP; Duvick L; Mitchell JS; Cvetanovic M; Reighard M; Soles A; Mather KB; Rainwater O; Serres S; Nichols-Meade T; Coffin SL; You Y; Ruis BL; O'Callaghan B; Henzler C; Zoghbi HY; Orr HT
    Neuron; 2023 Feb; 111(4):493-507.e6. PubMed ID: 36577403
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sphingolipid metabolism governs Purkinje cell patterned degeneration in
    Blot FGC; Krijnen WHJJ; Den Hoedt S; Osório C; White JJ; Mulder MT; Schonewille M
    Proc Natl Acad Sci U S A; 2021 Sep; 118(36):. PubMed ID: 34479994
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Purkinje cell ataxin-1 modulates climbing fiber synaptic input in developing and adult mouse cerebellum.
    Ebner BA; Ingram MA; Barnes JA; Duvick LA; Frisch JL; Clark HB; Zoghbi HY; Ebner TJ; Orr HT
    J Neurosci; 2013 Mar; 33(13):5806-20. PubMed ID: 23536093
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 5'UTR-mediated regulation of Ataxin-1 expression.
    Manek R; Nelson T; Tseng E; Rodriguez-Lebron E
    Neurobiol Dis; 2020 Feb; 134():104564. PubMed ID: 31381977
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Beyond the glutamine expansion: influence of posttranslational modifications of ataxin-1 in the pathogenesis of spinocerebellar ataxia type 1.
    Ju H; Kokubu H; Lim J
    Mol Neurobiol; 2014 Dec; 50(3):866-874. PubMed ID: 24752589
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A novel function of Ataxin-1 in the modulation of PP2A activity is dysregulated in the spinocerebellar ataxia type 1.
    Sánchez I; Piñol P; Corral-Juan M; Pandolfo M; Matilla-Dueñas A
    Hum Mol Genet; 2013 Sep; 22(17):3425-37. PubMed ID: 23630944
    [TBL] [Abstract][Full Text] [Related]  

  • 19. BIIB021, a synthetic Hsp90 inhibitor, induces mutant ataxin-1 degradation through the activation of heat shock factor 1.
    Ding Y; Adachi H; Katsuno M; Sahashi K; Kondo N; Iida M; Tohnai G; Nakatsuji H; Sobue G
    Neuroscience; 2016 Jul; 327():20-31. PubMed ID: 27058144
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Therapeutic Strategies for Spinocerebellar Ataxia Type 1.
    Kerkhof LMC; van de Warrenburg BPC; van Roon-Mom WMC; Buijsen RAM
    Biomolecules; 2023 May; 13(5):. PubMed ID: 37238658
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.