267 related articles for article (PubMed ID: 34768811)
1. A Promiscuous Bacterial P450: The Unparalleled Diversity of BM3 in Pharmaceutical Metabolism.
Thistlethwaite S; Jeffreys LN; Girvan HM; McLean KJ; Munro AW
Int J Mol Sci; 2021 Oct; 22(21):. PubMed ID: 34768811
[TBL] [Abstract][Full Text] [Related]
2. Application of engineered cytochrome P450 mutants as biocatalysts for the synthesis of benzylic and aromatic metabolites of fenamic acid NSAIDs.
Venkataraman H; Verkade-Vreeker MC; Capoferri L; Geerke DP; Vermeulen NP; Commandeur JN
Bioorg Med Chem; 2014 Oct; 22(20):5613-20. PubMed ID: 24999003
[TBL] [Abstract][Full Text] [Related]
3. The bacterial P450 BM3: a prototype for a biocatalyst with human P450 activities.
Yun CH; Kim KH; Kim DH; Jung HC; Pan JG
Trends Biotechnol; 2007 Jul; 25(7):289-98. PubMed ID: 17532492
[TBL] [Abstract][Full Text] [Related]
4. Flavocytochrome P450 BM3 mutant W1046A is a NADH-dependent fatty acid hydroxylase: implications for the mechanism of electron transfer in the P450 BM3 dimer.
Girvan HM; Dunford AJ; Neeli R; Ekanem IS; Waltham TN; Joyce MG; Leys D; Curtis RA; Williams P; Fisher K; Voice MW; Munro AW
Arch Biochem Biophys; 2011 Mar; 507(1):75-85. PubMed ID: 20868649
[TBL] [Abstract][Full Text] [Related]
5. Control of the stereo-selectivity of styrene epoxidation by cytochrome P450 BM3 using structure-based mutagenesis.
Huang WC; Cullis PM; Raven EL; Roberts GC
Metallomics; 2011 Apr; 3(4):410-6. PubMed ID: 21240430
[TBL] [Abstract][Full Text] [Related]
6. Oleic acid based experimental evolution of Bacillus megaterium yielding an enhanced P450 BM3 variant.
Vincent T; Gaillet B; Garnier A
BMC Biotechnol; 2022 Jul; 22(1):20. PubMed ID: 35831844
[TBL] [Abstract][Full Text] [Related]
7. Flavocytochrome P450 BM3: an update on structure and mechanism of a biotechnologically important enzyme.
Warman AJ; Roitel O; Neeli R; Girvan HM; Seward HE; Murray SA; McLean KJ; Joyce MG; Toogood H; Holt RA; Leys D; Scrutton NS; Munro AW
Biochem Soc Trans; 2005 Aug; 33(Pt 4):747-53. PubMed ID: 16042591
[TBL] [Abstract][Full Text] [Related]
8. Analysis of the oxidation of short chain alkynes by flavocytochrome P450 BM3.
Waltham TN; Girvan HM; Butler CF; Rigby SR; Dunford AJ; Holt RA; Munro AW
Metallomics; 2011 Apr; 3(4):369-78. PubMed ID: 21431175
[TBL] [Abstract][Full Text] [Related]
9. A novel semi-biosynthetic route for artemisinin production using engineered substrate-promiscuous P450(BM3).
Dietrich JA; Yoshikuni Y; Fisher KJ; Woolard FX; Ockey D; McPhee DJ; Renninger NS; Chang MC; Baker D; Keasling JD
ACS Chem Biol; 2009 Apr; 4(4):261-7. PubMed ID: 19271725
[TBL] [Abstract][Full Text] [Related]
10. Human P450-like oxidation of diverse proton pump inhibitor drugs by 'gatekeeper' mutants of flavocytochrome P450 BM3.
Butler CF; Peet C; McLean KJ; Baynham MT; Blankley RT; Fisher K; Rigby SE; Leys D; Voice MW; Munro AW
Biochem J; 2014 Jun; 460(2):247-59. PubMed ID: 24588219
[TBL] [Abstract][Full Text] [Related]
11. Key mutations alter the cytochrome P450 BM3 conformational landscape and remove inherent substrate bias.
Butler CF; Peet C; Mason AE; Voice MW; Leys D; Munro AW
J Biol Chem; 2013 Aug; 288(35):25387-25399. PubMed ID: 23828198
[TBL] [Abstract][Full Text] [Related]
12. Optimization of the bacterial cytochrome P450 BM3 system for the production of human drug metabolites.
Di Nardo G; Gilardi G
Int J Mol Sci; 2012 Nov; 13(12):15901-24. PubMed ID: 23443101
[TBL] [Abstract][Full Text] [Related]
13. Expression, purification, and characterization of Bacillus subtilis cytochromes P450 CYP102A2 and CYP102A3: flavocytochrome homologues of P450 BM3 from Bacillus megaterium.
Gustafsson MC; Roitel O; Marshall KR; Noble MA; Chapman SK; Pessegueiro A; Fulco AJ; Cheesman MR; von Wachenfeldt C; Munro AW
Biochemistry; 2004 May; 43(18):5474-87. PubMed ID: 15122913
[TBL] [Abstract][Full Text] [Related]
14. Glutamate-haem ester bond formation is disfavoured in flavocytochrome P450 BM3: characterization of glutamate substitution mutants at the haem site of P450 BM3.
Girvan HM; Levy CW; Williams P; Fisher K; Cheesman MR; Rigby SE; Leys D; Munro AW
Biochem J; 2010 Apr; 427(3):455-66. PubMed ID: 20180779
[TBL] [Abstract][Full Text] [Related]
15. The role of cytochrome P450 BM3 phenylalanine-87 and threonine-268 in binding organic hydroperoxides.
Roberts AG; Katayama J; Kaspera R; Ledwitch KV; Le Trong I; Stenkamp RE; Thompson JA; Totah RA
Biochim Biophys Acta; 2016 Apr; 1860(4):669-77. PubMed ID: 26723172
[TBL] [Abstract][Full Text] [Related]
16. Engineering bacterial cytochrome P450 (P450) BM3 into a prototype with human P450 enzyme activity using indigo formation.
Park SH; Kim DH; Kim D; Kim DH; Jung HC; Pan JG; Ahn T; Kim D; Yun CH
Drug Metab Dispos; 2010 May; 38(5):732-9. PubMed ID: 20100815
[TBL] [Abstract][Full Text] [Related]
17. Analysis of the interactions of cytochrome b5 with flavocytochrome P450 BM3 and its domains.
Noble MA; Girvan HM; Smith SJ; Smith WE; Murataliev M; Guzov VM; Feyereisen R; Munro AW
Drug Metab Rev; 2007; 39(2-3):599-617. PubMed ID: 17786641
[TBL] [Abstract][Full Text] [Related]
18. Highly regioselective hydroxylation of polydatin, a resveratrol glucoside, for one-step synthesis of astringin, a piceatannol glucoside, by P450 BM3.
Le TK; Jang HH; Nguyen HT; Doan TT; Lee GY; Park KD; Ahn T; Joung YH; Kang HS; Yun CH
Enzyme Microb Technol; 2017 Feb; 97():34-42. PubMed ID: 28010771
[TBL] [Abstract][Full Text] [Related]
19. Genetic fusion of P450 BM3 and formate dehydrogenase towards self-sufficient biocatalysts with enhanced activity.
Kokorin A; Parshin PD; Bakkes PJ; Pometun AA; Tishkov VI; Urlacher VB
Sci Rep; 2021 Nov; 11(1):21706. PubMed ID: 34737365
[TBL] [Abstract][Full Text] [Related]
20. Generation of human metabolites of 7-ethoxycoumarin by bacterial cytochrome P450 BM3.
Kim DH; Kim KH; Kim DH; Liu KH; Jung HC; Pan JG; Yun CH
Drug Metab Dispos; 2008 Nov; 36(11):2166-70. PubMed ID: 18669587
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
