BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

207 related articles for article (PubMed ID: 34771714)

  • 1. H3.3K27M Mutation Controls Cell Growth and Resistance to Therapies in Pediatric Glioma Cell Lines.
    Rakotomalala A; Bailleul Q; Savary C; Arcicasa M; Hamadou M; Huchedé P; Hochart A; Restouin A; Castellano R; Collette Y; Dieny E; Vincent A; Angrand PO; Le Bourhis X; Leblond P; Furlan A; Castets M; Pasquier E; Meignan S
    Cancers (Basel); 2021 Nov; 13(21):. PubMed ID: 34771714
    [TBL] [Abstract][Full Text] [Related]  

  • 2. H3F3A K27M Mutations Drives a Repressive Transcriptome by Modulating Chromatin Accessibility, Independent of H3K27me3 in Diffuse Midline Glioma.
    Bhattarai S; Hakkim FL; Day CA; Grigore F; Langfald A; Entin I; Hinchcliffe EH; Robinson JP
    bioRxiv; 2024 May; ():. PubMed ID: 38798502
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A novel mouse model of diffuse midline glioma initiated in neonatal oligodendrocyte progenitor cells highlights cell-of-origin dependent effects of H3K27M.
    Tomita Y; Shimazu Y; Somasundaram A; Tanaka Y; Takata N; Ishi Y; Gadd S; Hashizume R; Angione A; Pinero G; Hambardzumyan D; Brat DJ; Hoeman CM; Becher OJ
    Glia; 2022 Sep; 70(9):1681-1698. PubMed ID: 35524725
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression.
    Chan KM; Fang D; Gan H; Hashizume R; Yu C; Schroeder M; Gupta N; Mueller S; James CD; Jenkins R; Sarkaria J; Zhang Z
    Genes Dev; 2013 May; 27(9):985-90. PubMed ID: 23603901
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Epigenome Programming by H3.3K27M Mutation Creates a Dependence of Pediatric Glioma on SMARCA4.
    Mo Y; Duan S; Zhang X; Hua X; Zhou H; Wei HJ; Watanabe J; McQuillan N; Su Z; Gu W; Wu CC; Vakoc CR; Hashizume R; Chang K; Zhang Z
    Cancer Discov; 2022 Dec; 12(12):2906-2929. PubMed ID: 36305747
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Histone H3.3K27M Mobilizes Multiple Cancer/Testis (CT) Antigens in Pediatric Glioma.
    Deng H; Zeng J; Zhang T; Gong L; Zhang H; Cheung E; Jones C; Li G
    Mol Cancer Res; 2018 Apr; 16(4):623-633. PubMed ID: 29453317
    [TBL] [Abstract][Full Text] [Related]  

  • 7. H2A.Z histone variants facilitate HDACi-dependent removal of H3.3K27M mutant protein in pediatric high-grade glioma cells.
    Leszczynska KB; Freitas-Huhtamäki A; Jayaprakash C; Dzwigonska M; Vitorino FNL; Horth C; Wojnicki K; Gielniewski B; Szadkowska P; Kaza B; Nazarian J; Ciolkowski MK; Trubicka J; Grajkowska W; Garcia BA; Majewski J; Kaminska B; Mieczkowski J
    Cell Rep; 2024 Feb; 43(2):113707. PubMed ID: 38306270
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Antisense oligonucleotide therapy for H3.3K27M diffuse midline glioma.
    Zhang Q; Yang L; Liu YH; Wilkinson JE; Krainer AR
    Sci Transl Med; 2023 Apr; 15(691):eadd8280. PubMed ID: 37043556
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Histone deposition pathways determine the chromatin landscapes of H3.1 and H3.3 K27M oncohistones.
    Sarthy JF; Meers MP; Janssens DH; Henikoff JG; Feldman H; Paddison PJ; Lockwood CM; Vitanza NA; Olson JM; Ahmad K; Henikoff S
    Elife; 2020 Sep; 9():. PubMed ID: 32902381
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Detection of histone H3 K27M mutation and post-translational modifications in pediatric diffuse midline glioma via tissue immunohistochemistry informs diagnosis and clinical outcomes.
    Huang T; Garcia R; Qi J; Lulla R; Horbinski C; Behdad A; Wadhwani N; Shilatifard A; James C; Saratsis AM
    Oncotarget; 2018 Dec; 9(98):37112-37124. PubMed ID: 30647848
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Standardization of the liquid biopsy for pediatric diffuse midline glioma using ddPCR.
    Li D; Bonner ER; Wierzbicki K; Panditharatna E; Huang T; Lulla R; Mueller S; Koschmann C; Nazarian J; Saratsis AM
    Sci Rep; 2021 Mar; 11(1):5098. PubMed ID: 33658570
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Histone H3.3 K27M chromatin functions implicate a network of neurodevelopmental factors including ASCL1 and NEUROD1 in DIPG.
    Lewis NA; Klein RH; Kelly C; Yee J; Knoepfler PS
    Epigenetics Chromatin; 2022 May; 15(1):18. PubMed ID: 35590427
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Epigenetic activation of a RAS/MYC axis in H3.3K27M-driven cancer.
    Pajovic S; Siddaway R; Bridge T; Sheth J; Rakopoulos P; Kim B; Ryall S; Agnihotri S; Phillips L; Yu M; Li C; Milos S; Patel P; Srikanthan D; Huang A; Hawkins C
    Nat Commun; 2020 Dec; 11(1):6216. PubMed ID: 33277484
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Histone H3.3K27M Represses
    Cordero FJ; Huang Z; Grenier C; He X; Hu G; McLendon RE; Murphy SK; Hashizume R; Becher OJ
    Mol Cancer Res; 2017 Sep; 15(9):1243-1254. PubMed ID: 28522693
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A lesson learned from the H3.3K27M mutation found in pediatric glioma: a new approach to the study of the function of histone modifications in vivo?
    Chan KM; Han J; Fang D; Gan H; Zhang Z
    Cell Cycle; 2013 Aug; 12(16):2546-52. PubMed ID: 23907119
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cooperativity between H3.3K27M and PDGFRA poses multiple therapeutic vulnerabilities in human iPSC-derived diffuse midline glioma avatars.
    Skinner KR; Koga T; Miki S; Gruener RF; Grigore FN; Torii EH; Seelig DM; Suzuki Y; Kawauchi D; Lin B; Malicki DM; Chen CC; Benveniste EN; Patel RP; McFarland BC; Huang RS; Jones C; Mackay A; Miller CR; Furnari FB
    bioRxiv; 2023 Feb; ():. PubMed ID: 36865329
    [TBL] [Abstract][Full Text] [Related]  

  • 17. H3F3A K27M Mutation Promotes the Infiltrative Growth of High-Grade Glioma in Adults by Activating β-Catenin/USP1 Signaling.
    Sun Z; Zhu Y; Feng X; Liu X; Zhou K; Wang Q; Zhang H; Shi H
    Cancers (Basel); 2022 Oct; 14(19):. PubMed ID: 36230759
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Endogenous H3.3K27M derived peptide restricted to HLA-A∗02:01 is insufficient for immune-targeting in diffuse midline glioma.
    Wang SS; Pandey K; Watson KA; Abbott RC; Mifsud NA; Gracey FM; Ramarathinam SH; Cross RS; Purcell AW; Jenkins MR
    Mol Ther Oncolytics; 2023 Sep; 30():167-180. PubMed ID: 37674626
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Histone H3K27M Mutation in Brain Tumors.
    El-Hashash AHK
    Adv Exp Med Biol; 2021; 1283():43-52. PubMed ID: 33155136
    [TBL] [Abstract][Full Text] [Related]  

  • 20. INTERCEPT H3: a multicenter phase I peptide vaccine trial for the treatment of H3-mutated diffuse midline gliomas.
    Grassl N; Sahm K; Süße H; Poschke I; Bunse L; Bunse T; Boschert T; Mildenberger I; Rupp AK; Ewinger MP; Lanz LM; Denk M; Tabatabai G; Ronellenfitsch MW; Herrlinger U; Glas M; Krex D; Vajkoczy P; Wick A; Harting I; Sahm F; von Deimling A; Bendszus M; Wick W; Platten M
    Neurol Res Pract; 2023 Oct; 5(1):55. PubMed ID: 37853454
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.