307 related articles for article (PubMed ID: 34774801)
1. Phase-separated protein droplets of amyotrophic lateral sclerosis-associated p62/SQSTM1 mutants show reduced inner fluidity.
Faruk MO; Ichimura Y; Kageyama S; Komatsu-Hirota S; El-Gowily AH; Sou YS; Koike M; Noda NN; Komatsu M
J Biol Chem; 2021 Dec; 297(6):101405. PubMed ID: 34774801
[TBL] [Abstract][Full Text] [Related]
2. ALS-FTLD associated mutations of SQSTM1 impact on Keap1-Nrf2 signalling.
Goode A; Rea S; Sultana M; Shaw B; Searle MS; Layfield R
Mol Cell Neurosci; 2016 Oct; 76():52-58. PubMed ID: 27554286
[TBL] [Abstract][Full Text] [Related]
3. ALS-FTLD-linked mutations of SQSTM1/p62 disrupt selective autophagy and NFE2L2/NRF2 anti-oxidative stress pathway.
Deng Z; Lim J; Wang Q; Purtell K; Wu S; Palomo GM; Tan H; Manfredi G; Zhao Y; Peng J; Hu B; Chen S; Yue Z
Autophagy; 2020 May; 16(5):917-931. PubMed ID: 31362587
[TBL] [Abstract][Full Text] [Related]
4. An FTLD-associated SQSTM1 variant impacts Nrf2 and NF-κB signalling and is associated with reduced phosphorylation of p62.
Foster A; Scott D; Layfield R; Rea SL
Mol Cell Neurosci; 2019 Jul; 98():32-45. PubMed ID: 30954537
[TBL] [Abstract][Full Text] [Related]
5. NBR1-mediated p62-liquid droplets enhance the Keap1-Nrf2 system.
Sánchez-Martín P; Sou YS; Kageyama S; Koike M; Waguri S; Komatsu M
EMBO Rep; 2020 Mar; 21(3):e48902. PubMed ID: 31916398
[TBL] [Abstract][Full Text] [Related]
6. Negative Regulation of the Keap1-Nrf2 Pathway by a p62/Sqstm1 Splicing Variant.
Kageyama S; Saito T; Obata M; Koide RH; Ichimura Y; Komatsu M
Mol Cell Biol; 2018 Apr; 38(7):. PubMed ID: 29339380
[TBL] [Abstract][Full Text] [Related]
7. p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription.
Jain A; Lamark T; Sjøttem E; Larsen KB; Awuh JA; Øvervatn A; McMahon M; Hayes JD; Johansen T
J Biol Chem; 2010 Jul; 285(29):22576-91. PubMed ID: 20452972
[TBL] [Abstract][Full Text] [Related]
8. Effect of p62/SQSTM1 polyubiquitination on its autophagic adaptor function and cellular survival under oxidative stress induced by arsenite.
Lee H; Kim MN; Ryu KY
Biochem Biophys Res Commun; 2017 May; 486(3):839-844. PubMed ID: 28359760
[TBL] [Abstract][Full Text] [Related]
9. ALS-associated TBK1 variant p.G175S is defective in phosphorylation of p62 and impacts TBK1-mediated signalling and TDP-43 autophagic degradation.
Foster AD; Downing P; Figredo E; Polain N; Stott A; Layfield R; Rea SL
Mol Cell Neurosci; 2020 Oct; 108():103539. PubMed ID: 32835772
[TBL] [Abstract][Full Text] [Related]
10. P62/SQSTM1 upregulates NQO1 transcription via Nrf2/Keap1a signaling pathway to resist microcystins-induced oxidative stress in freshwater mussel Cristaria plicata.
Wu J; Hou S; Yang L; Wang Y; Wen C; Guo Y; Luo S; Fang H; Jiao H; Xu H; Zhang S
Aquat Toxicol; 2023 Feb; 255():106398. PubMed ID: 36669434
[TBL] [Abstract][Full Text] [Related]
11. p62/SQSTM1 protects against cisplatin-induced oxidative stress in kidneys by mediating the cross talk between autophagy and the Keap1-Nrf2 signalling pathway.
Liao W; Wang Z; Fu Z; Ma H; Jiang M; Xu A; Zhang W
Free Radic Res; 2019 Jul; 53(7):800-814. PubMed ID: 31223046
[TBL] [Abstract][Full Text] [Related]
12. Defective recognition of LC3B by mutant SQSTM1/p62 implicates impairment of autophagy as a pathogenic mechanism in ALS-FTLD.
Goode A; Butler K; Long J; Cavey J; Scott D; Shaw B; Sollenberger J; Gell C; Johansen T; Oldham NJ; Searle MS; Layfield R
Autophagy; 2016 Jul; 12(7):1094-104. PubMed ID: 27158844
[TBL] [Abstract][Full Text] [Related]
13. Functional links between SQSTM1 and ALS2 in the pathogenesis of ALS: cumulative impact on the protection against mutant SOD1-mediated motor dysfunction in mice.
Hadano S; Mitsui S; Pan L; Otomo A; Kubo M; Sato K; Ono S; Onodera W; Abe K; Chen X; Koike M; Uchiyama Y; Aoki M; Warabi E; Yamamoto M; Ishii T; Yanagawa T; Shang HF; Yoshii F
Hum Mol Genet; 2016 Aug; 25(15):3321-3340. PubMed ID: 27439389
[TBL] [Abstract][Full Text] [Related]
14. Retinoic acid worsens ATG10-dependent autophagy impairment in TBK1-mutant hiPSC-derived motoneurons through SQSTM1/p62 accumulation.
Catanese A; Olde Heuvel F; Mulaw M; Demestre M; Higelin J; Barbi G; Freischmidt A; Weishaupt JH; Ludolph AC; Roselli F; Boeckers TM
Autophagy; 2019 Oct; 15(10):1719-1737. PubMed ID: 30939964
[TBL] [Abstract][Full Text] [Related]
15. p62/SQSTM1-droplet serves as a platform for autophagosome formation and anti-oxidative stress response.
Kageyama S; Gudmundsson SR; Sou YS; Ichimura Y; Tamura N; Kazuno S; Ueno T; Miura Y; Noshiro D; Abe M; Mizushima T; Miura N; Okuda S; Motohashi H; Lee JA; Sakimura K; Ohe T; Noda NN; Waguri S; Eskelinen EL; Komatsu M
Nat Commun; 2021 Jan; 12(1):16. PubMed ID: 33397898
[TBL] [Abstract][Full Text] [Related]
16. SPOP mutations promote p62/SQSTM1-dependent autophagy and Nrf2 activation in prostate cancer.
Shi Q; Jin X; Zhang P; Li Q; Lv Z; Ding Y; He H; Wang Y; He Y; Zhao X; Zhao SM; Li Y; Gao K; Wang C
Cell Death Differ; 2022 Jun; 29(6):1228-1239. PubMed ID: 34987184
[TBL] [Abstract][Full Text] [Related]
17. p62-Dependent Phase Separation of Patient-Derived KEAP1 Mutations and NRF2.
Cloer EW; Siesser PF; Cousins EM; Goldfarb D; Mowrey DD; Harrison JS; Weir SJ; Dokholyan NV; Major MB
Mol Cell Biol; 2018 Nov; 38(22):. PubMed ID: 30126895
[TBL] [Abstract][Full Text] [Related]
18. MOAP-1-mediated dissociation of p62/SQSTM1 bodies releases Keap1 and suppresses Nrf2 signaling.
Tan CT; Chang HC; Zhou Q; Yu C; Fu NY; Sabapathy K; Yu VC
EMBO Rep; 2021 Jan; 22(1):e50854. PubMed ID: 33393215
[TBL] [Abstract][Full Text] [Related]
19. TAK1 Regulates the Nrf2 Antioxidant System Through Modulating p62/SQSTM1.
Hashimoto K; Simmons AN; Kajino-Sakamoto R; Tsuji Y; Ninomiya-Tsuji J
Antioxid Redox Signal; 2016 Dec; 25(17):953-964. PubMed ID: 27245349
[TBL] [Abstract][Full Text] [Related]
20. Neuropathy-causing mutations in HSPB1 impair autophagy by disturbing the formation of SQSTM1/p62 bodies.
Haidar M; Asselbergh B; Adriaenssens E; De Winter V; Timmermans JP; Auer-Grumbach M; Juneja M; Timmerman V
Autophagy; 2019 Jun; 15(6):1051-1068. PubMed ID: 30669930
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
