BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

145 related articles for article (PubMed ID: 34778935)

  • 1. Investigating the in vitro steatotic mixture effects of similarly and dissimilarly acting test compounds using an adverse outcome pathway-based approach.
    Alarcan J; de Sousa G; Katsanou ES; Spyropoulou A; Batakis P; Machera K; Rahmani R; Lampen A; Braeuning A; Lichtenstein D
    Arch Toxicol; 2022 Jan; 96(1):211-229. PubMed ID: 34778935
    [TBL] [Abstract][Full Text] [Related]  

  • 2. An adverse outcome pathway-based approach to assess steatotic mixture effects of hepatotoxic pesticides in vitro.
    Lichtenstein D; Luckert C; Alarcan J; de Sousa G; Gioutlakis M; Katsanou ES; Konstantinidou P; Machera K; Milani ES; Peijnenburg A; Rahmani R; Rijkers D; Spyropoulou A; Stamou M; Stoopen G; Sturla SJ; Wollscheid B; Zucchini-Pascal N; Braeuning A; Lampen A
    Food Chem Toxicol; 2020 May; 139():111283. PubMed ID: 32201337
    [TBL] [Abstract][Full Text] [Related]  

  • 3. More than additive effects on liver triglyceride accumulation by combinations of steatotic and non-steatotic pesticides in HepaRG cells.
    Lasch A; Marx-Stoelting P; Braeuning A; Lichtenstein D
    Arch Toxicol; 2021 Apr; 95(4):1397-1411. PubMed ID: 33575850
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Adverse Outcome Pathway-Driven Analysis of Liver Steatosis in Vitro: A Case Study with Cyproconazole.
    Luckert C; Braeuning A; de Sousa G; Durinck S; Katsanou ES; Konstantinidou P; Machera K; Milani ES; Peijnenburg AACM; Rahmani R; Rajkovic A; Rijkers D; Spyropoulou A; Stamou M; Stoopen G; Sturla S; Wollscheid B; Zucchini-Pascal N; Lampen A
    Chem Res Toxicol; 2018 Aug; 31(8):784-798. PubMed ID: 29995386
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pregnane X receptor mediates steatotic effects of propiconazole and tebuconazole in human liver cell lines.
    Knebel C; Buhrke T; Süssmuth R; Lampen A; Marx-Stoelting P; Braeuning A
    Arch Toxicol; 2019 May; 93(5):1311-1322. PubMed ID: 30989312
    [TBL] [Abstract][Full Text] [Related]  

  • 6. An eight-compound mixture but not corresponding concentrations of individual chemicals induces triglyceride accumulation in human liver cells.
    Lichtenstein D; Lasch A; Alarcan J; Mentz A; Kalinowski J; Schmidt FF; Pötz O; Marx-Stoelting P; Braeuning A
    Toxicology; 2021 Jul; 459():152857. PubMed ID: 34273450
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Advantageous use of HepaRG cells for the screening and mechanistic study of drug-induced steatosis.
    Tolosa L; Gómez-Lechón MJ; Jiménez N; Hervás D; Jover R; Donato MT
    Toxicol Appl Pharmacol; 2016 Jul; 302():1-9. PubMed ID: 27089845
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Integrate mechanistic evidence from new approach methodologies (NAMs) into a read-across assessment to characterise trends in shared mode of action.
    Escher SE; Aguayo-Orozco A; Benfenati E; Bitsch A; Braunbeck T; Brotzmann K; Bois F; van der Burg B; Castel J; Exner T; Gadaleta D; Gardner I; Goldmann D; Hatley O; Golbamaki N; Graepel R; Jennings P; Limonciel A; Long A; Maclennan R; Mombelli E; Norinder U; Jain S; Capinha LS; Taboureau OT; Tolosa L; Vrijenhoek NG; van Vugt-Lussenburg BMA; Walker P; van de Water B; Wehr M; White A; Zdrazil B; Fisher C
    Toxicol In Vitro; 2022 Mar; 79():105269. PubMed ID: 34757180
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of exendin-4-induced steatosis by protein kinase A in cultured HepG2 human hepatoma cells.
    Chen-Liaw AY; Hammel G; Gomez G
    In Vitro Cell Dev Biol Anim; 2017 Sep; 53(8):721-727. PubMed ID: 28707223
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Combinations of LXR and RXR agonists induce triglyceride accumulation in human HepaRG cells in a synergistic manner.
    Lasch A; Alarcan J; Lampen A; Braeuning A; Lichtenstein D
    Arch Toxicol; 2020 Apr; 94(4):1303-1320. PubMed ID: 32123961
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Editor's Highlight: Mechanistic Toxicity Tests Based on an Adverse Outcome Pathway Network for Hepatic Steatosis.
    Angrish MM; McQueen CA; Cohen-Hubal E; Bruno M; Ge Y; Chorley BN
    Toxicol Sci; 2017 Sep; 159(1):159-169. PubMed ID: 28903485
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Regulation of Drug Metabolism by the Interplay of Inflammatory Signaling, Steatosis, and Xeno-Sensing Receptors in HepaRG Cells.
    Tanner N; Kubik L; Luckert C; Thomas M; Hofmann U; Zanger UM; Böhmert L; Lampen A; Braeuning A
    Drug Metab Dispos; 2018 Apr; 46(4):326-335. PubMed ID: 29330220
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Adverse outcome pathway-based analysis of liver steatosis in vitro using human liver cell lines.
    Karaca M; Fritsche K; Lichtenstein D; Vural Ö; Kreuzer K; Alarcan J; Braeuning A; Marx-Stoelting P; Tralau T
    STAR Protoc; 2023 Sep; 4(3):102500. PubMed ID: 37616165
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Transcript and protein marker patterns for the identification of steatotic compounds in human HepaRG cells.
    Lichtenstein D; Mentz A; Schmidt FF; Luckert C; Buhrke T; Marx-Stoelting P; Kalinowski J; Albaum SP; Joos TO; Poetz O; Braeuning A
    Food Chem Toxicol; 2020 Nov; 145():111690. PubMed ID: 32810590
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Estimation of toxicity of chemical mixtures through modeling of chemical interactions.
    Mumtaz MM; De Rosa CT; Groten J; Feron VJ; Hansen H; Durkin PR
    Environ Health Perspect; 1998 Dec; 106 Suppl 6(Suppl 6):1353-60. PubMed ID: 9860892
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Peroxisome proliferator-activated receptor α activation induces hepatic steatosis, suggesting an adverse effect.
    Yan F; Wang Q; Xu C; Cao M; Zhou X; Wang T; Yu C; Jing F; Chen W; Gao L; Zhao J
    PLoS One; 2014; 9(6):e99245. PubMed ID: 24926685
    [TBL] [Abstract][Full Text] [Related]  

  • 17. An adverse outcome pathway based in vitro characterization of novel flame retardants-induced hepatic steatosis.
    Negi CK; Bajard L; Kohoutek J; Blaha L
    Environ Pollut; 2021 Nov; 289():117855. PubMed ID: 34340181
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Selecting mixtures on the basis of dietary exposure and hazard data: application to pesticide exposure in the European population in relation to steatosis.
    Crépet A; Vanacker M; Sprong C; de Boer W; Blaznik U; Kennedy M; Anagnostopoulos C; Christodoulou DL; Ruprich J; Rehurkova I; Domingo JL; Hamborg Jensen B; Metruccio F; Moretto A; Jacxsens L; Spanoghe P; Senaeve D; van der Voet H; van Klaveren J
    Int J Hyg Environ Health; 2019 Mar; 222(2):291-306. PubMed ID: 30579770
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Induction of vesicular steatosis by amiodarone and tetracycline is associated with up-regulation of lipogenic genes in HepaRG cells.
    Anthérieu S; Rogue A; Fromenty B; Guillouzo A; Robin MA
    Hepatology; 2011 Jun; 53(6):1895-905. PubMed ID: 21391224
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A human hepatocellular in vitro model to investigate steatosis.
    Gómez-Lechón MJ; Donato MT; Martínez-Romero A; Jiménez N; Castell JV; O'Connor JE
    Chem Biol Interact; 2007 Jan; 165(2):106-16. PubMed ID: 17188672
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.