BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

286 related articles for article (PubMed ID: 34782635)

  • 1. Gene editing with CRISPR-Cas12a guides possessing ribose-modified pseudoknot handles.
    Ageely EA; Chilamkurthy R; Jana S; Abdullahu L; O'Reilly D; Jensik PJ; Damha MJ; Gagnon KT
    Nat Commun; 2021 Nov; 12(1):6591. PubMed ID: 34782635
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A Survey of Genome Editing Activity for 16 Cas12a Orthologs.
    Zetsche B; Abudayyeh OO; Gootenberg JS; Scott DA; Zhang F
    Keio J Med; 2020 Sep; 69(3):59-65. PubMed ID: 31723075
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Editor's cut: DNA cleavage by CRISPR RNA-guided nucleases Cas9 and Cas12a.
    Swartjes T; Staals RHJ; van der Oost J
    Biochem Soc Trans; 2020 Feb; 48(1):207-219. PubMed ID: 31872209
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Multiplexed conditional genome editing with Cas12a in
    Port F; Starostecka M; Boutros M
    Proc Natl Acad Sci U S A; 2020 Sep; 117(37):22890-22899. PubMed ID: 32843348
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mechanics of CRISPR-Cas12a and engineered variants on λ-DNA.
    Paul B; Chaubet L; Verver DE; Montoya G
    Nucleic Acids Res; 2022 May; 50(9):5208-5225. PubMed ID: 34951457
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Expanding the scope of plant genome engineering with Cas12a orthologs and highly multiplexable editing systems.
    Zhang Y; Ren Q; Tang X; Liu S; Malzahn AA; Zhou J; Wang J; Yin D; Pan C; Yuan M; Huang L; Yang H; Zhao Y; Fang Q; Zheng X; Tian L; Cheng Y; Le Y; McCoy B; Franklin L; Selengut JD; Mount SM; Que Q; Zhang Y; Qi Y
    Nat Commun; 2021 Mar; 12(1):1944. PubMed ID: 33782402
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design and Evaluation of Guide RNA Transcripts with a 3'-Terminal HDV Ribozyme to Enhance CRISPR-Based Gene Inactivation.
    Berkhout B; Gao Z; Herrera-Carrillo E
    Methods Mol Biol; 2021; 2167():205-224. PubMed ID: 32712922
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Highly efficient and safe genome editing by CRISPR-Cas12a using CRISPR RNA with a ribosyl-2'-O-methylated uridinylate-rich 3'-overhang in mouse zygotes.
    Ha DI; Lee JM; Lee NE; Kim D; Ko JH; Kim YS
    Exp Mol Med; 2020 Nov; 52(11):1823-1830. PubMed ID: 33162553
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Combined genome editing and transcriptional repression for metabolic pathway engineering in Corynebacterium glutamicum using a catalytically active Cas12a.
    Liu W; Tang D; Wang H; Lian J; Huang L; Xu Z
    Appl Microbiol Biotechnol; 2019 Nov; 103(21-22):8911-8922. PubMed ID: 31583448
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Enhancement of target specificity of CRISPR-Cas12a by using a chimeric DNA-RNA guide.
    Kim H; Lee WJ; Oh Y; Kang SH; Hur JK; Lee H; Song W; Lim KS; Park YH; Song BS; Jin YB; Jun BH; Jung C; Lee DS; Kim SU; Lee SH
    Nucleic Acids Res; 2020 Sep; 48(15):8601-8616. PubMed ID: 32687187
    [TBL] [Abstract][Full Text] [Related]  

  • 11. High-performance CRISPR-Cas12a genome editing for combinatorial genetic screening.
    Gier RA; Budinich KA; Evitt NH; Cao Z; Freilich ES; Chen Q; Qi J; Lan Y; Kohli RM; Shi J
    Nat Commun; 2020 Jul; 11(1):3455. PubMed ID: 32661245
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Gene Manipulation Using Fusion Guide RNAs for Cas9 and Cas12a.
    Shin HR; Kweon J; Kim Y
    Methods Mol Biol; 2021; 2162():185-193. PubMed ID: 32926383
    [TBL] [Abstract][Full Text] [Related]  

  • 13. CRISPR-Cas12a has widespread off-target and dsDNA-nicking effects.
    Murugan K; Seetharam AS; Severin AJ; Sashital DG
    J Biol Chem; 2020 Apr; 295(17):5538-5553. PubMed ID: 32161115
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12a.
    Swarts DC; van der Oost J; Jinek M
    Mol Cell; 2017 Apr; 66(2):221-233.e4. PubMed ID: 28431230
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mechanistic Insights into the cis- and trans-Acting DNase Activities of Cas12a.
    Swarts DC; Jinek M
    Mol Cell; 2019 Feb; 73(3):589-600.e4. PubMed ID: 30639240
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Establishment of a Cleavage-Based Single-Plasmid Dual-Luciferase Surrogate Reporter for the Cleavage Efficiency Evaluation of CRISPR-Cas12a Systems and Its Primary Application.
    Shi Y; Tan Q; Yang C; Li S; Li Y; He B; Xie H; Duan X; Chen L
    CRISPR J; 2024 Jun; 7(3):156-167. PubMed ID: 38922054
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Gene Disruption Using Chemically Modified CRISPR-Cpf1 RNA.
    McMahon MA; Rahdar M
    Methods Mol Biol; 2021; 2162():49-60. PubMed ID: 32926377
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Optimization of AsCas12a for combinatorial genetic screens in human cells.
    DeWeirdt PC; Sanson KR; Sangree AK; Hegde M; Hanna RE; Feeley MN; Griffith AL; Teng T; Borys SM; Strand C; Joung JK; Kleinstiver BP; Pan X; Huang A; Doench JG
    Nat Biotechnol; 2021 Jan; 39(1):94-104. PubMed ID: 32661438
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The bridge helix of Cas12a imparts selectivity in cis-DNA cleavage and regulates trans-DNA cleavage.
    Parameshwaran HP; Babu K; Tran C; Guan K; Allen A; Kathiresan V; Qin PZ; Rajan R
    FEBS Lett; 2021 Apr; 595(7):892-912. PubMed ID: 33523494
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Harnessing noncanonical crRNA for highly efficient genome editing.
    Xun G; Zhu Z; Singh N; Lu J; Jain PK; Zhao H
    Nat Commun; 2024 May; 15(1):3823. PubMed ID: 38714643
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.