These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

172 related articles for article (PubMed ID: 34783037)

  • 21. Does prenylation predict progression in NAFLD?
    Ghorbani P; Smith TK; Fullerton MD
    J Pathol; 2019 Mar; 247(3):283-286. PubMed ID: 30374976
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Inhibition of farnesyl pyrophosphate (FPP) and/or geranylgeranyl pyrophosphate (GGPP) biosynthesis and its implication in the treatment of cancers.
    Waller DD; Park J; Tsantrizos YS
    Crit Rev Biochem Mol Biol; 2019 Feb; 54(1):41-60. PubMed ID: 30773935
    [TBL] [Abstract][Full Text] [Related]  

  • 23. High-content assay to study protein prenylation.
    Simonen M; Ibig-Rehm Y; Hofmann G; Zimmermann J; Albrecht G; Magnier M; Heidinger V; Gabriel D
    J Biomol Screen; 2008 Jul; 13(6):456-67. PubMed ID: 18509097
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras.
    Luckman SP; Hughes DE; Coxon FP; Graham R; Russell G; Rogers MJ
    J Bone Miner Res; 1998 Apr; 13(4):581-9. PubMed ID: 9556058
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The balance of protein farnesylation and geranylgeranylation during the progression of nonalcoholic fatty liver disease.
    Zhao Y; Wu TY; Zhao MF; Li CJ
    J Biol Chem; 2020 Apr; 295(15):5152-5162. PubMed ID: 32139507
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Isoprenoids, small GTPases and Alzheimer's disease.
    Hooff GP; Wood WG; Müller WE; Eckert GP
    Biochim Biophys Acta; 2010 Aug; 1801(8):896-905. PubMed ID: 20382260
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Deciphering the signaling networks underlying simvastatin-induced apoptosis in human cancer cells: evidence for non-canonical activation of RhoA and Rac1 GTPases.
    Zhu Y; Casey PJ; Kumar AP; Pervaiz S
    Cell Death Dis; 2013 Apr; 4(4):e568. PubMed ID: 23559002
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Murine guanylate-binding protein: incomplete geranylgeranyl isoprenoid modification of an interferon-gamma-inducible guanosine triphosphate-binding protein.
    Stickney JT; Buss JE
    Mol Biol Cell; 2000 Jul; 11(7):2191-200. PubMed ID: 10888661
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Propiconazole-enhanced hepatic cell proliferation is associated with dysregulation of the cholesterol biosynthesis pathway leading to activation of Erk1/2 through Ras farnesylation.
    Murphy LA; Moore T; Nesnow S
    Toxicol Appl Pharmacol; 2012 Apr; 260(2):146-54. PubMed ID: 22361350
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Molecular mechanisms linking geranylgeranyl diphosphate synthase to cell survival and proliferation.
    Agabiti SS; Liang Y; Wiemer AJ
    Mol Membr Biol; 2016 Mar; 33(1-2):1-11. PubMed ID: 27537059
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Alteration of mevalonate pathway related enzyme expressions in pressure overload-induced cardiac hypertrophy and associated heart failure with preserved ejection fraction.
    Chen B; Zhong LY; Yang JX; Pan YY; Chen F; Yang J; Wu T; Hu SJ
    Cell Physiol Biochem; 2013; 32(6):1761-75. PubMed ID: 24356578
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Mevalonate Pathway Blockade, Mitochondrial Dysfunction and Autophagy: A Possible Link.
    Tricarico PM; Crovella S; Celsi F
    Int J Mol Sci; 2015 Jul; 16(7):16067-84. PubMed ID: 26184189
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Simvastatin inhibits T-cell activation by selectively impairing the function of Ras superfamily GTPases.
    Ghittoni R; Patrussi L; Pirozzi K; Pellegrini M; Lazzerini PE; Capecchi PL; Pasini FL; Baldari CT
    FASEB J; 2005 Apr; 19(6):605-7. PubMed ID: 15677697
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Inhibition of farnesyl pyrophosphate synthase attenuates angiotensin II-induced cardiac hypertrophy and fibrosis in vivo.
    Yang J; Zhu HH; Chen GP; Ye Y; Zhao CZ; Mou Y; Hu SJ
    Int J Biochem Cell Biol; 2013 Mar; 45(3):657-66. PubMed ID: 23277274
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Regulation of fatty acid synthesis by farnesyl pyrophosphate.
    Murthy S; Tong H; Hohl RJ
    J Biol Chem; 2005 Dec; 280(51):41793-804. PubMed ID: 16221687
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Targeting the mevalonate pathway for improved anticancer therapy.
    Fritz G
    Curr Cancer Drug Targets; 2009 Aug; 9(5):626-38. PubMed ID: 19508172
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Targeting Small GTPases and Their Prenylation in Diabetes Mellitus.
    Gendaszewska-Darmach E; Garstka MA; Błażewska KM
    J Med Chem; 2021 Jul; 64(14):9677-9710. PubMed ID: 34236862
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Statins inhibit blastocyst formation by preventing geranylgeranylation.
    Alarcon VB; Marikawa Y
    Mol Hum Reprod; 2016 May; 22(5):350-63. PubMed ID: 26908642
    [TBL] [Abstract][Full Text] [Related]  

  • 39. The Ras-related protein Rheb is farnesylated and antagonizes Ras signaling and transformation.
    Clark GJ; Kinch MS; Rogers-Graham K; Sebti SM; Hamilton AD; Der CJ
    J Biol Chem; 1997 Apr; 272(16):10608-15. PubMed ID: 9099708
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Identifying Potential Therapeutics for Osteoporosis by Exploiting the Relationship between Mevalonate Pathway and Bone Metabolism.
    Hasan WNW; Chin KY; Jolly JJ; Ghafar NA; Soelaiman IN
    Endocr Metab Immune Disord Drug Targets; 2018; 18(5):450-457. PubMed ID: 29683099
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.