BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

323 related articles for article (PubMed ID: 34789849)

  • 1. Schizophrenia is defined by cell-specific neuropathology and multiple neurodevelopmental mechanisms in patient-derived cerebral organoids.
    Notaras M; Lodhi A; Dündar F; Collier P; Sayles NM; Tilgner H; Greening D; Colak D
    Mol Psychiatry; 2022 Mar; 27(3):1416-1434. PubMed ID: 34789849
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The proteomic architecture of schizophrenia iPSC-derived cerebral organoids reveals alterations in GWAS and neuronal development factors.
    Notaras M; Lodhi A; Fang H; Greening D; Colak D
    Transl Psychiatry; 2021 Oct; 11(1):541. PubMed ID: 34667143
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Schizophrenia endothelial cells exhibit higher permeability and altered angiogenesis patterns in patient-derived organoids.
    Stankovic I; Notaras M; Wolujewicz P; Lu T; Lis R; Ross ME; Colak D
    Transl Psychiatry; 2024 Jan; 14(1):53. PubMed ID: 38263175
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A Robust Pipeline for the Multi-Stage Accelerated Differentiation of Functional 3D Cortical Organoids from Human Pluripotent Stem Cells.
    Whye D; Wood D; Saber WA; Norabuena EM; Makhortova NR; Sahin M; Buttermore ED
    Curr Protoc; 2023 Jan; 3(1):e641. PubMed ID: 36633423
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Transcription factor POU3F2 regulates TRIM8 expression contributing to cellular functions implicated in schizophrenia.
    Ding C; Zhang C; Kopp R; Kuney L; Meng Q; Wang L; Xia Y; Jiang Y; Dai R; Min S; Yao WD; Wong ML; Ruan H; Liu C; Chen C
    Mol Psychiatry; 2021 Jul; 26(7):3444-3460. PubMed ID: 32929213
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Comparative Transcriptomic Analysis of Cerebral Organoids and Cortical Neuron Cultures Derived from Human Induced Pluripotent Stem Cells.
    Kathuria A; Lopez-Lengowski K; Watmuff B; Karmacharya R
    Stem Cells Dev; 2020 Nov; 29(21):1370-1381. PubMed ID: 32862797
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Transcriptomic Landscape and Functional Characterization of Induced Pluripotent Stem Cell-Derived Cerebral Organoids in Schizophrenia.
    Kathuria A; Lopez-Lengowski K; Jagtap SS; McPhie D; Perlis RH; Cohen BM; Karmacharya R
    JAMA Psychiatry; 2020 Jul; 77(7):745-754. PubMed ID: 32186681
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Impact of schizophrenia GWAS loci converge onto distinct pathways in cortical interneurons vs glutamatergic neurons during development.
    Liu D; Zinski A; Mishra A; Noh H; Park GH; Qin Y; Olorife O; Park JM; Abani CP; Park JS; Fung J; Sawaqed F; Coyle JT; Stahl E; Bendl J; Fullard JF; Roussos P; Zhang X; Stanton PK; Yin C; Huang W; Kim HY; Won H; Cho JH; Chung S
    Mol Psychiatry; 2022 Oct; 27(10):4218-4233. PubMed ID: 35701597
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Recapitulation of Perturbed Striatal Gene Expression Dynamics of Donors' Brains With Ventral Forebrain Organoids Derived From the Same Individuals With Schizophrenia.
    Sawada T; Barbosa AR; Araujo B; McCord AE; D'Ignazio L; Benjamin KJM; Sheehan B; Zabolocki M; Feltrin A; Arora R; Brandtjen AC; Kleinman JE; Hyde TM; Bardy C; Weinberger DR; Paquola ACM; Erwin JA
    Am J Psychiatry; 2024 Jun; 181(6):493-511. PubMed ID: 37915216
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Probing the molecular and cellular pathological mechanisms of schizophrenia using human induced pluripotent stem cell models.
    Sebastian R; Song Y; Pak C
    Schizophr Res; 2022 Jul; ():. PubMed ID: 35835709
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Neurodevelopmental signatures of narcotic and neuropsychiatric risk factors in 3D human-derived forebrain organoids.
    Notaras M; Lodhi A; Barrio-Alonso E; Foord C; Rodrick T; Jones D; Fang H; Greening D; Colak D
    Mol Psychiatry; 2021 Dec; 26(12):7760-7783. PubMed ID: 34158620
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Proteomic signatures of schizophrenia-sourced iPSC-derived neural cells and brain organoids are similar to patients' postmortem brains.
    Nascimento JM; Saia-Cereda VM; Zuccoli GS; Reis-de-Oliveira G; Carregari VC; Smith BJ; Rehen SK; Martins-de-Souza D
    Cell Biosci; 2022 Dec; 12(1):189. PubMed ID: 36451159
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Excitatory Dysfunction Drives Network and Calcium Handling Deficits in 16p11.2 Duplication Schizophrenia Induced Pluripotent Stem Cell-Derived Neurons.
    Parnell E; Culotta L; Forrest MP; Jalloul HA; Eckman BL; Loizzo DD; Horan KKE; Dos Santos M; Piguel NH; Tai DJC; Zhang H; Gertler TS; Simkin D; Sanders AR; Talkowski ME; Gejman PV; Kiskinis E; Duan J; Penzes P
    Biol Psychiatry; 2023 Jul; 94(2):153-163. PubMed ID: 36581494
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Generation of iPSC-derived Human Brain Organoids to Model Early Neurodevelopmental Disorders.
    Gabriel E; Gopalakrishnan J
    J Vis Exp; 2017 Apr; (122):. PubMed ID: 28448044
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Schizophrenia-associated NRXN1 deletions induce developmental-timing- and cell-type-specific vulnerabilities in human brain organoids.
    Sebastian R; Jin K; Pavon N; Bansal R; Potter A; Song Y; Babu J; Gabriel R; Sun Y; Aronow B; Pak C
    Nat Commun; 2023 Jun; 14(1):3770. PubMed ID: 37355690
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A human iPSC-astroglia neurodevelopmental model reveals divergent transcriptomic patterns in schizophrenia.
    Szabo A; Akkouh IA; Vandenberghe M; Osete JR; Hughes T; Heine V; Smeland OB; Glover JC; Andreassen OA; Djurovic S
    Transl Psychiatry; 2021 Oct; 11(1):554. PubMed ID: 34716291
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Longitudinal Transcriptomic Analysis of Human Cortical Spheroids Identifies Axonal Dysregulation in the Prenatal Brain as a Mediator of Genetic Risk for Schizophrenia.
    Akkouh IA; Ueland T; Szabo A; Hughes T; Smeland OB; Andreassen OA; Osete JR; Djurovic S
    Biol Psychiatry; 2024 Apr; 95(7):687-698. PubMed ID: 37661009
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Transcriptome analysis reveals disparate expression of inflammation-related miRNAs and their gene targets in iPSC-astrocytes from people with schizophrenia.
    Akkouh IA; Hughes T; Steen VM; Glover JC; Andreassen OA; Djurovic S; Szabo A
    Brain Behav Immun; 2021 May; 94():235-244. PubMed ID: 33571628
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Current progress in understanding schizophrenia using genomics and pluripotent stem cells: A meta-analytical overview.
    Choudhary A; Peles D; Nayak R; Mizrahi L; Stern S
    Schizophr Res; 2022 Nov; ():. PubMed ID: 36443183
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Transcriptomic Mapping of Neural Diversity, Differentiation and Functional Trajectory in iPSC-Derived 3D Brain Organoid Models.
    Kiaee K; Jodat YA; Bassous NJ; Matharu N; Shin SR
    Cells; 2021 Dec; 10(12):. PubMed ID: 34943930
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.