BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

245 related articles for article (PubMed ID: 34790781)

  • 41. DRP1 Inhibition Enhances Venetoclax-Induced Mitochondrial Apoptosis in TP53-Mutated Acute Myeloid Leukemia Cells through BAX/BAK Activation.
    Jang JE; Hwang DY; Eom JI; Cheong JW; Jeung HK; Cho H; Chung H; Kim JS; Min YH
    Cancers (Basel); 2023 Jan; 15(3):. PubMed ID: 36765703
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Inhibition of CPT1a as a prognostic marker can synergistically enhance the antileukemic activity of ABT199.
    Mao S; Ling Q; Pan J; Li F; Huang S; Ye W; Wei W; Lin X; Qian Y; Wang Y; Huang X; Huang J; Wang J; Jin J
    J Transl Med; 2021 Apr; 19(1):181. PubMed ID: 33926484
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Metformin sensitizes AML cells to venetoclax through endoplasmic reticulum stress-CHOP pathway.
    Hua L; Yang N; Li Y; Huang K; Jiang X; Liu F; Yu Z; Chen J; Lai J; Du J; Zeng H
    Br J Haematol; 2023 Sep; 202(5):971-984. PubMed ID: 37409755
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Chidamide in FLT3-ITD positive acute myeloid leukemia and the synergistic effect in combination with cytarabine.
    Li X; Yan X; Guo W; Huang X; Huang J; Yu M; Ma Z; Xu Y; Huang S; Li C; Zhou Y; Jin J
    Biomed Pharmacother; 2017 Jun; 90():699-704. PubMed ID: 28419965
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Dual inhibition of Bcl-2 and Bcl-xL strikingly enhances PI3K inhibition-induced apoptosis in human myeloid leukemia cells through a GSK3- and Bim-dependent mechanism.
    Rahmani M; Aust MM; Attkisson E; Williams DC; Ferreira-Gonzalez A; Grant S
    Cancer Res; 2013 Feb; 73(4):1340-51. PubMed ID: 23243017
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Genetic biomarkers predict response to dual BCL-2 and MCL-1 targeting in acute myeloid leukaemia cells.
    Grundy M; Balakrishnan S; Fox M; Seedhouse CH; Russell NH
    Oncotarget; 2018 Dec; 9(102):37777-37789. PubMed ID: 30701031
    [TBL] [Abstract][Full Text] [Related]  

  • 47. A combination of low-dose decitabine and chidamide resulted in synergistic effects on the proliferation and apoptosis of human myeloid leukemia cell lines.
    Xu F; Guo H; Shi M; Liu S; Wei M; Sun K; Chen Y
    Am J Transl Res; 2019; 11(12):7644-7655. PubMed ID: 31934307
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Side-by-side comparison of BH3-mimetics identifies MCL-1 as a key therapeutic target in AML.
    Ewald L; Dittmann J; Vogler M; Fulda S
    Cell Death Dis; 2019 Dec; 10(12):917. PubMed ID: 31801941
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Venetoclax combines synergistically with FLT3 inhibition to effectively target leukemic cells in FLT3-ITD+ acute myeloid leukemia models.
    Singh Mali R; Zhang Q; DeFilippis RA; Cavazos A; Kuruvilla VM; Raman J; Mody V; Choo EF; Dail M; Shah NP; Konopleva M; Sampath D; Lasater EA
    Haematologica; 2021 Apr; 106(4):1034-1046. PubMed ID: 32414851
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Targeted therapy with a selective BCL-2 inhibitor in older patients with acute myeloid leukemia.
    Campos EDV; Pinto R
    Hematol Transfus Cell Ther; 2019; 41(2):169-177. PubMed ID: 31084767
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Venetoclax-Resistant MV4-11 Leukemic Cells Activate PI3K/AKT Pathway for Metabolic Reprogramming and Redox Adaptation for Survival.
    Alkhatabi HA; Zohny SF; Shait Mohammed MR; Choudhry H; Rehan M; Ahmad A; Ahmed F; Khan MI
    Antioxidants (Basel); 2022 Feb; 11(3):. PubMed ID: 35326111
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Inhibition of CDK9 by voruciclib synergistically enhances cell death induced by the Bcl-2 selective inhibitor venetoclax in preclinical models of acute myeloid leukemia.
    Luedtke DA; Su Y; Ma J; Li X; Buck SA; Edwards H; Polin L; Kushner J; Dzinic SH; White K; Lin H; Taub JW; Ge Y
    Signal Transduct Target Ther; 2020 Feb; 5(1):17. PubMed ID: 32296028
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Venetoclax in Acute Myeloid Leukemia.
    Mihăilă RG
    Recent Pat Anticancer Drug Discov; 2023; 18(1):11-28. PubMed ID: 35507786
    [TBL] [Abstract][Full Text] [Related]  

  • 54. The HDAC and PI3K dual inhibitor CUDC-907 synergistically enhances the antileukemic activity of venetoclax in preclinical models of acute myeloid leukemia.
    Li X; Su Y; Hege K; Madlambayan G; Edwards H; Knight T; Polin L; Kushner J; Dzinic SH; White K; Yang J; Miller R; Wang G; Zhao L; Wang Y; Lin H; Taub JW; Ge Y
    Haematologica; 2021 May; 106(5):1262-1277. PubMed ID: 32165486
    [TBL] [Abstract][Full Text] [Related]  

  • 55. The Bcl-2 inhibitor venetoclax inhibits Nrf2 antioxidant pathway activation induced by hypomethylating agents in AML.
    Nguyen LXT; Troadec E; Kalvala A; Kumar B; Hoang DH; Viola D; Zhang B; Nguyen DQ; Aldoss I; Ghoda L; Budde E; Pichiorri F; Rosen S; Forman SJ; Marcucci G; Pullarkat V
    J Cell Physiol; 2019 Aug; 234(8):14040-14049. PubMed ID: 30623427
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Combating Acute Myeloid Leukemia via Sphingosine Kinase 1 Inhibitor-Nanomedicine Combination Therapy with Cytarabine or Venetoclax.
    Nguyen TM; Joyce P; Ross DM; Bremmell K; Jambhrunkar M; Wong SS; Prestidge CA
    Pharmaceutics; 2024 Jan; 16(2):. PubMed ID: 38399263
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Durable remissions with venetoclax monotherapy in secondary AML refractory to hypomethylating agents and high expression of BCL-2 and/or BIM.
    Huemer F; Melchardt T; Jansko B; Wahida A; Jilg S; Jost PJ; Klieser E; Steiger K; Magnes T; Pleyer L; Greil-Ressler S; Rass C; Greil R; Egle A
    Eur J Haematol; 2019 May; 102(5):437-441. PubMed ID: 30725494
    [TBL] [Abstract][Full Text] [Related]  

  • 58. AMP-Activated Protein Kinase Contributes to Apoptosis Induced by the Bcl-2 Inhibitor Venetoclax in Acute Myeloid Leukemia.
    Legrand N; Pradier A; Poulain L; Mouche S; Birsen R; Larrue C; Simonetta F; Tamburini J
    Cancers (Basel); 2021 Nov; 13(23):. PubMed ID: 34885077
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Cotargeting of Mitochondrial Complex I and Bcl-2 Shows Antileukemic Activity against Acute Myeloid Leukemia Cells Reliant on Oxidative Phosphorylation.
    Liu F; Kalpage HA; Wang D; Edwards H; Hüttemann M; Ma J; Su Y; Carter J; Li X; Polin L; Kushner J; Dzinic SH; White K; Wang G; Taub JW; Ge Y
    Cancers (Basel); 2020 Aug; 12(9):. PubMed ID: 32847115
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Formononetin and Dihydroartemisinin Act Synergistically to Induce Apoptosis in Human Acute Myeloid Leukemia Cell Lines.
    Abbasi Y; Pooladi M; Nazmabadi R; Amri J; Abbasi H; Karami H
    Cell J; 2024 Feb; 26(2):121-129. PubMed ID: 38459729
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 13.