377 related articles for article (PubMed ID: 34791698)
21. Translation of dipeptide repeat proteins from the C9ORF72 expanded repeat is associated with cellular stress.
Sonobe Y; Ghadge G; Masaki K; Sendoel A; Fuchs E; Roos RP
Neurobiol Dis; 2018 Aug; 116():155-165. PubMed ID: 29792928
[TBL] [Abstract][Full Text] [Related]
22. Repeat-associated non-AUG translation in C9orf72-ALS/FTD is driven by neuronal excitation and stress.
Westergard T; McAvoy K; Russell K; Wen X; Pang Y; Morris B; Pasinelli P; Trotti D; Haeusler A
EMBO Mol Med; 2019 Feb; 11(2):. PubMed ID: 30617154
[TBL] [Abstract][Full Text] [Related]
23. C9orf72 and RAB7L1 regulate vesicle trafficking in amyotrophic lateral sclerosis and frontotemporal dementia.
Aoki Y; Manzano R; Lee Y; Dafinca R; Aoki M; Douglas AGL; Varela MA; Sathyaprakash C; Scaber J; Barbagallo P; Vader P; Mäger I; Ezzat K; Turner MR; Ito N; Gasco S; Ohbayashi N; El Andaloussi S; Takeda S; Fukuda M; Talbot K; Wood MJA
Brain; 2017 Apr; 140(4):887-897. PubMed ID: 28334866
[TBL] [Abstract][Full Text] [Related]
24. Inflammasome-Mediated Neuronal-Microglial Crosstalk: a Therapeutic Substrate for the Familial C9orf72 Variant of Frontotemporal Dementia/Amyotrophic Lateral Sclerosis.
Trageser KJ; Yang EJ; Smith C; Iban-Arias R; Oguchi T; Sebastian-Valverde M; Iqbal UH; Wu H; Estill M; Al Rahim M; Raval U; Herman FJ; Zhang YJ; Petrucelli L; Pasinetti GM
Mol Neurobiol; 2023 Jul; 60(7):4004-4016. PubMed ID: 37010807
[TBL] [Abstract][Full Text] [Related]
25. UBQLN2-HSP70 axis reduces poly-Gly-Ala aggregates and alleviates behavioral defects in the C9ORF72 animal model.
Zhang K; Wang A; Zhong K; Qi S; Wei C; Shu X; Tu WY; Xu W; Xia C; Xiao Y; Chen A; Bai L; Zhang J; Luo B; Wang W; Shen C
Neuron; 2021 Jun; 109(12):1949-1962.e6. PubMed ID: 33991504
[TBL] [Abstract][Full Text] [Related]
26. A feedback loop between dipeptide-repeat protein, TDP-43 and karyopherin-α mediates C9orf72-related neurodegeneration.
Solomon DA; Stepto A; Au WH; Adachi Y; Diaper DC; Hall R; Rekhi A; Boudi A; Tziortzouda P; Lee YB; Smith B; Bridi JC; Spinelli G; Dearlove J; Humphrey DM; Gallo JM; Troakes C; Fanto M; Soller M; Rogelj B; Parsons RB; Shaw CE; Hortobágyi T; Hirth F
Brain; 2018 Oct; 141(10):2908-2924. PubMed ID: 30239641
[TBL] [Abstract][Full Text] [Related]
27. Co-expression of C9orf72 related dipeptide-repeats over 1000 repeat units reveals age- and combination-specific phenotypic profiles in Drosophila.
West RJH; Sharpe JL; Voelzmann A; Munro AL; Hahn I; Baines RA; Pickering-Brown S
Acta Neuropathol Commun; 2020 Sep; 8(1):158. PubMed ID: 32894207
[TBL] [Abstract][Full Text] [Related]
28. PolyGR and polyPR knock-in mice reveal a conserved neuroprotective extracellular matrix signature in C9orf72 ALS/FTD neurons.
Milioto C; Carcolé M; Giblin A; Coneys R; Attrebi O; Ahmed M; Harris SS; Lee BI; Yang M; Ellingford RA; Nirujogi RS; Biggs D; Salomonsson S; Zanovello M; de Oliveira P; Katona E; Glaria I; Mikheenko A; Geary B; Udine E; Vaizoglu D; Anoar S; Jotangiya K; Crowley G; Smeeth DM; Adams ML; Niccoli T; Rademakers R; van Blitterswijk M; Devoy A; Hong S; Partridge L; Coyne AN; Fratta P; Alessi DR; Davies B; Busche MA; Greensmith L; Fisher EMC; Isaacs AM
Nat Neurosci; 2024 Apr; 27(4):643-655. PubMed ID: 38424324
[TBL] [Abstract][Full Text] [Related]
29. Arginine-rich dipeptide-repeat proteins as phase disruptors in C9-ALS/FTD.
Odeh HM; Shorter J
Emerg Top Life Sci; 2020 Dec; 4(3):293-305. PubMed ID: 32639008
[TBL] [Abstract][Full Text] [Related]
30. The nuclear ubiquitin ligase adaptor SPOP is a conserved regulator of C9orf72 dipeptide toxicity.
Snoznik C; Medvedeva V; Mojsilovic-Petrovic J; Rudich P; Oosten J; Kalb RG; Lamitina T
Proc Natl Acad Sci U S A; 2021 Oct; 118(40):. PubMed ID: 34593637
[TBL] [Abstract][Full Text] [Related]
31. The carboxyl termini of RAN translated GGGGCC nucleotide repeat expansions modulate toxicity in models of ALS/FTD.
He F; Flores BN; Krans A; Frazer M; Natla S; Niraula S; Adefioye O; Barmada SJ; Todd PK
Acta Neuropathol Commun; 2020 Aug; 8(1):122. PubMed ID: 32753055
[TBL] [Abstract][Full Text] [Related]
32. CRISPR-Cas9 Screens Identify the RNA Helicase DDX3X as a Repressor of C9ORF72 (GGGGCC)n Repeat-Associated Non-AUG Translation.
Cheng W; Wang S; Zhang Z; Morgens DW; Hayes LR; Lee S; Portz B; Xie Y; Nguyen BV; Haney MS; Yan S; Dong D; Coyne AN; Yang J; Xian F; Cleveland DW; Qiu Z; Rothstein JD; Shorter J; Gao FB; Bassik MC; Sun S
Neuron; 2019 Dec; 104(5):885-898.e8. PubMed ID: 31587919
[TBL] [Abstract][Full Text] [Related]
33. A cell-penetrant peptide blocking
Castelli LM; Lin YH; Sanchez-Martinez A; Gül A; Mohd Imran K; Higginbottom A; Upadhyay SK; Márkus NM; Rua Martins R; Cooper-Knock J; Montmasson C; Cohen R; Walton A; Bauer CS; De Vos KJ; Mead RJ; Azzouz M; Dominguez C; Ferraiuolo L; Shaw PJ; Whitworth AJ; Hautbergue GM
Sci Transl Med; 2023 Mar; 15(685):eabo3823. PubMed ID: 36857431
[TBL] [Abstract][Full Text] [Related]
34. Evidence that C9ORF72 Dipeptide Repeat Proteins Associate with U2 snRNP to Cause Mis-splicing in ALS/FTD Patients.
Yin S; Lopez-Gonzalez R; Kunz RC; Gangopadhyay J; Borufka C; Gygi SP; Gao FB; Reed R
Cell Rep; 2017 Jun; 19(11):2244-2256. PubMed ID: 28614712
[TBL] [Abstract][Full Text] [Related]
35. Stable transgenic C9orf72 zebrafish model key aspects of the ALS/FTD phenotype and reveal novel pathological features.
Shaw MP; Higginbottom A; McGown A; Castelli LM; James E; Hautbergue GM; Shaw PJ; Ramesh TM
Acta Neuropathol Commun; 2018 Nov; 6(1):125. PubMed ID: 30454072
[TBL] [Abstract][Full Text] [Related]
36. RNA dependent suppression of C9orf72 ALS/FTD associated neurodegeneration by Matrin-3.
Ramesh N; Daley EL; Gleixner AM; Mann JR; Kour S; Mawrie D; Anderson EN; Kofler J; Donnelly CJ; Kiskinis E; Pandey UB
Acta Neuropathol Commun; 2020 Oct; 8(1):177. PubMed ID: 33129345
[TBL] [Abstract][Full Text] [Related]
37. Repeated repeat problems: Combinatorial effect of C9orf72-derived dipeptide repeat proteins.
Darling AL; Breydo L; Rivas EG; Gebru NT; Zheng D; Baker JD; Blair LJ; Dickey CA; Koren J; Uversky VN
Int J Biol Macromol; 2019 Apr; 127():136-145. PubMed ID: 30639592
[TBL] [Abstract][Full Text] [Related]
38. Downregulation of Hsp90 and the antimicrobial peptide Mtk suppresses poly(GR)-induced neurotoxicity in C9ORF72-ALS/FTD.
Lee S; Jun YW; Linares GR; Butler B; Yuva-Adyemir Y; Moore J; Krishnan G; Ruiz-Juarez B; Santana M; Pons M; Silverman N; Weng Z; Ichida JK; Gao FB
Neuron; 2023 May; 111(9):1381-1390.e6. PubMed ID: 36931278
[TBL] [Abstract][Full Text] [Related]
39. Human C9ORF72 Hexanucleotide Expansion Reproduces RNA Foci and Dipeptide Repeat Proteins but Not Neurodegeneration in BAC Transgenic Mice.
Peters OM; Cabrera GT; Tran H; Gendron TF; McKeon JE; Metterville J; Weiss A; Wightman N; Salameh J; Kim J; Sun H; Boylan KB; Dickson D; Kennedy Z; Lin Z; Zhang YJ; Daughrity L; Jung C; Gao FB; Sapp PC; Horvitz HR; Bosco DA; Brown SP; de Jong P; Petrucelli L; Mueller C; Brown RH
Neuron; 2015 Dec; 88(5):902-909. PubMed ID: 26637797
[TBL] [Abstract][Full Text] [Related]
40. Nuclear export and translation of circular repeat-containing intronic RNA in C9ORF72-ALS/FTD.
Wang S; Latallo MJ; Zhang Z; Huang B; Bobrovnikov DG; Dong D; Livingston NM; Tjoeng W; Hayes LR; Rothstein JD; Ostrow LW; Wu B; Sun S
Nat Commun; 2021 Aug; 12(1):4908. PubMed ID: 34389711
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
