339 related articles for article (PubMed ID: 34791698)
41. Human C9ORF72 Hexanucleotide Expansion Reproduces RNA Foci and Dipeptide Repeat Proteins but Not Neurodegeneration in BAC Transgenic Mice.
Peters OM; Cabrera GT; Tran H; Gendron TF; McKeon JE; Metterville J; Weiss A; Wightman N; Salameh J; Kim J; Sun H; Boylan KB; Dickson D; Kennedy Z; Lin Z; Zhang YJ; Daughrity L; Jung C; Gao FB; Sapp PC; Horvitz HR; Bosco DA; Brown SP; de Jong P; Petrucelli L; Mueller C; Brown RH
Neuron; 2015 Dec; 88(5):902-909. PubMed ID: 26637797
[TBL] [Abstract][Full Text] [Related]
42. RNA dependent suppression of C9orf72 ALS/FTD associated neurodegeneration by Matrin-3.
Ramesh N; Daley EL; Gleixner AM; Mann JR; Kour S; Mawrie D; Anderson EN; Kofler J; Donnelly CJ; Kiskinis E; Pandey UB
Acta Neuropathol Commun; 2020 Oct; 8(1):177. PubMed ID: 33129345
[TBL] [Abstract][Full Text] [Related]
43. FUS regulates RAN translation through modulating the G-quadruplex structure of GGGGCC repeat RNA in
Fujino Y; Ueyama M; Ishiguro T; Ozawa D; Ito H; Sugiki T; Murata A; Ishiguro A; Gendron T; Mori K; Tokuda E; Taminato T; Konno T; Koyama A; Kawabe Y; Takeuchi T; Furukawa Y; Fujiwara T; Ikeda M; Mizuno T; Mochizuki H; Mizusawa H; Wada K; Ishikawa K; Onodera O; Nakatani K; Petrucelli L; Taguchi H; Nagai Y
Elife; 2023 Jul; 12():. PubMed ID: 37461319
[TBL] [Abstract][Full Text] [Related]
44. Differential Toxicity of Nuclear RNA Foci versus Dipeptide Repeat Proteins in a Drosophila Model of C9ORF72 FTD/ALS.
Tran H; Almeida S; Moore J; Gendron TF; Chalasani U; Lu Y; Du X; Nickerson JA; Petrucelli L; Weng Z; Gao FB
Neuron; 2015 Sep; 87(6):1207-1214. PubMed ID: 26402604
[TBL] [Abstract][Full Text] [Related]
45. The small heat shock protein B8 (HSPB8) efficiently removes aggregating species of dipeptides produced in C9ORF72-related neurodegenerative diseases.
Cristofani R; Crippa V; Vezzoli G; Rusmini P; Galbiati M; Cicardi ME; Meroni M; Ferrari V; Tedesco B; Piccolella M; Messi E; Carra S; Poletti A
Cell Stress Chaperones; 2018 Jan; 23(1):1-12. PubMed ID: 28608264
[TBL] [Abstract][Full Text] [Related]
46. A zebrafish model for C9orf72 ALS reveals RNA toxicity as a pathogenic mechanism.
Swinnen B; Bento-Abreu A; Gendron TF; Boeynaems S; Bogaert E; Nuyts R; Timmers M; Scheveneels W; Hersmus N; Wang J; Mizielinska S; Isaacs AM; Petrucelli L; Lemmens R; Van Damme P; Van Den Bosch L; Robberecht W
Acta Neuropathol; 2018 Mar; 135(3):427-443. PubMed ID: 29302778
[TBL] [Abstract][Full Text] [Related]
47. Poly-GP in cerebrospinal fluid links
Lehmer C; Oeckl P; Weishaupt JH; Volk AE; Diehl-Schmid J; Schroeter ML; Lauer M; Kornhuber J; Levin J; Fassbender K; Landwehrmeyer B; ; Schludi MH; Arzberger T; Kremmer E; Flatley A; Feederle R; Steinacker P; Weydt P; Ludolph AC; Edbauer D; Otto M
EMBO Mol Med; 2017 Jul; 9(7):859-868. PubMed ID: 28408402
[TBL] [Abstract][Full Text] [Related]
48. Poly(GR) in C9ORF72-Related ALS/FTD Compromises Mitochondrial Function and Increases Oxidative Stress and DNA Damage in iPSC-Derived Motor Neurons.
Lopez-Gonzalez R; Lu Y; Gendron TF; Karydas A; Tran H; Yang D; Petrucelli L; Miller BL; Almeida S; Gao FB
Neuron; 2016 Oct; 92(2):383-391. PubMed ID: 27720481
[TBL] [Abstract][Full Text] [Related]
49. How villains are made: The translation of dipeptide repeat proteins in C9ORF72-ALS/FTD.
Van't Spijker HM; Almeida S
Gene; 2023 Mar; 858():147167. PubMed ID: 36621656
[TBL] [Abstract][Full Text] [Related]
50. Ribosomal quality control factors inhibit repeat-associated non-AUG translation from GC-rich repeats.
Tseng YJ; Krans A; Malik I; Deng X; Yildirim E; Ovunc S; Tank EMH; Jansen-West K; Kaufhold R; Gomez NB; Sher R; Petrucelli L; Barmada SJ; Todd PK
Nucleic Acids Res; 2024 Jun; 52(10):5928-5949. PubMed ID: 38412259
[TBL] [Abstract][Full Text] [Related]
51. Ribonuclease recruitment using a small molecule reduced c9ALS/FTD r(G
Bush JA; Aikawa H; Fuerst R; Li Y; Ursu A; Meyer SM; Benhamou RI; Chen JL; Khan T; Wagner-Griffin S; Van Meter MJ; Tong Y; Olafson H; McKee KK; Childs-Disney JL; Gendron TF; Zhang Y; Coyne AN; Wang ET; Yildirim I; Wang KW; Petrucelli L; Rothstein JD; Disney MD
Sci Transl Med; 2021 Oct; 13(617):eabd5991. PubMed ID: 34705518
[TBL] [Abstract][Full Text] [Related]
52. Transcription elongation factor AFF2/FMR2 regulates expression of expanded GGGGCC repeat-containing C9ORF72 allele in ALS/FTD.
Yuva-Aydemir Y; Almeida S; Krishnan G; Gendron TF; Gao FB
Nat Commun; 2019 Nov; 10(1):5466. PubMed ID: 31784536
[TBL] [Abstract][Full Text] [Related]
53. Synaptic dysfunction induced by glycine-alanine dipeptides in C9orf72-ALS/FTD is rescued by SV2 replenishment.
Jensen BK; Schuldi MH; McAvoy K; Russell KA; Boehringer A; Curran BM; Krishnamurthy K; Wen X; Westergard T; Ma L; Haeusler AR; Edbauer D; Pasinelli P; Trotti D
EMBO Mol Med; 2020 May; 12(5):e10722. PubMed ID: 32347002
[TBL] [Abstract][Full Text] [Related]
54. Soluble and insoluble dipeptide repeat protein measurements in C9orf72-frontotemporal dementia brains show regional differential solubility and correlation of poly-GR with clinical severity.
Quaegebeur A; Glaria I; Lashley T; Isaacs AM
Acta Neuropathol Commun; 2020 Nov; 8(1):184. PubMed ID: 33168090
[TBL] [Abstract][Full Text] [Related]
55. Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD.
Boeynaems S; Bogaert E; Michiels E; Gijselinck I; Sieben A; Jovičić A; De Baets G; Scheveneels W; Steyaert J; Cuijt I; Verstrepen KJ; Callaerts P; Rousseau F; Schymkowitz J; Cruts M; Van Broeckhoven C; Van Damme P; Gitler AD; Robberecht W; Van Den Bosch L
Sci Rep; 2016 Feb; 6():20877. PubMed ID: 26869068
[TBL] [Abstract][Full Text] [Related]
56. Pathogenic determinants and mechanisms of ALS/FTD linked to hexanucleotide repeat expansions in the C9orf72 gene.
Wen X; Westergard T; Pasinelli P; Trotti D
Neurosci Lett; 2017 Jan; 636():16-26. PubMed ID: 27619540
[TBL] [Abstract][Full Text] [Related]
57. C9orf72 Dipeptide Repeats Cause Selective Neurodegeneration and Cell-Autonomous Excitotoxicity in
Xu W; Xu J
J Neurosci; 2018 Aug; 38(35):7741-7752. PubMed ID: 30037833
[TBL] [Abstract][Full Text] [Related]
58. UPF1 reduces C9orf72 HRE-induced neurotoxicity in the absence of nonsense-mediated decay dysfunction.
Zaepfel BL; Zhang Z; Maulding K; Coyne AN; Cheng W; Hayes LR; Lloyd TE; Sun S; Rothstein JD
Cell Rep; 2021 Mar; 34(13):108925. PubMed ID: 33789100
[TBL] [Abstract][Full Text] [Related]
59. G-quadruplex-binding small molecules ameliorate
Simone R; Balendra R; Moens TG; Preza E; Wilson KM; Heslegrave A; Woodling NS; Niccoli T; Gilbert-Jaramillo J; Abdelkarim S; Clayton EL; Clarke M; Konrad MT; Nicoll AJ; Mitchell JS; Calvo A; Chio A; Houlden H; Polke JM; Ismail MA; Stephens CE; Vo T; Farahat AA; Wilson WD; Boykin DW; Zetterberg H; Partridge L; Wray S; Parkinson G; Neidle S; Patani R; Fratta P; Isaacs AM
EMBO Mol Med; 2018 Jan; 10(1):22-31. PubMed ID: 29113975
[TBL] [Abstract][Full Text] [Related]
60. Proline-arginine poly-dipeptide encoded by the C9orf72 repeat expansion inhibits adenosine deaminase acting on RNA.
Suzuki H; Matsuoka M
J Neurochem; 2021 Aug; 158(3):753-765. PubMed ID: 34081786
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]