BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

203 related articles for article (PubMed ID: 34792662)

  • 1. Cross-comparison of systemic and tissue-specific metabolomes in a mouse model of Leigh syndrome.
    Terburgh K; Lindeque JZ; van der Westhuizen FH; Louw R
    Metabolomics; 2021 Nov; 17(12):101. PubMed ID: 34792662
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Regional metabolic signatures in the Ndufs4(KO) mouse brain implicate defective glutamate/α-ketoglutarate metabolism in mitochondrial disease.
    Johnson SC; Kayser EB; Bornstein R; Stokes J; Bitto A; Park KY; Pan A; Sun G; Raftery D; Kaeberlein M; Sedensky MM; Morgan PG
    Mol Genet Metab; 2020 Jun; 130(2):118-132. PubMed ID: 32331968
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Aberrant BCAA and glutamate metabolism linked to regional neurodegeneration in a mouse model of Leigh syndrome.
    Terburgh K; Coetzer J; Lindeque JZ; van der Westhuizen FH; Louw R
    Biochim Biophys Acta Mol Basis Dis; 2021 May; 1867(5):166082. PubMed ID: 33486097
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Metabolomics of Ndufs4
    Terburgh K; Lindeque Z; Mason S; van der Westhuizen F; Louw R
    Biochim Biophys Acta Mol Basis Dis; 2019 Jan; 1865(1):98-106. PubMed ID: 30391276
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hypoxia ameliorates brain hyperoxia and NAD
    Grange RMH; Sharma R; Shah H; Reinstadler B; Goldberger O; Cooper MK; Nakagawa A; Miyazaki Y; Hindle AG; Batten AJ; Wojtkiewicz GR; Schleifer G; Bagchi A; Marutani E; Malhotra R; Bloch DB; Ichinose F; Mootha VK; Zapol WM
    Mol Genet Metab; 2021 May; 133(1):83-93. PubMed ID: 33752971
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Microglial response promotes neurodegeneration in the Ndufs4 KO mouse model of Leigh syndrome.
    Aguilar K; Comes G; Canal C; Quintana A; Sanz E; Hidalgo J
    Glia; 2022 Nov; 70(11):2032-2044. PubMed ID: 35770802
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Targeting NAD
    Lee CF; Caudal A; Abell L; Nagana Gowda GA; Tian R
    Sci Rep; 2019 Feb; 9(1):3073. PubMed ID: 30816177
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Miniaturized
    Mason S; Terburgh K; Louw R
    Metabolomics; 2018 May; 14(6):74. PubMed ID: 30830372
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Sub-Cellular Metabolomics Contributes Mitochondria-Specific Metabolic Insights to a Mouse Model of Leigh Syndrome.
    van der Walt G; Lindeque JZ; Mason S; Louw R
    Metabolites; 2021 Sep; 11(10):. PubMed ID: 34677373
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Region-Specific Defects of Respiratory Capacities in the Ndufs4(KO) Mouse Brain.
    Kayser EB; Sedensky MM; Morgan PG
    PLoS One; 2016; 11(1):e0148219. PubMed ID: 26824698
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Succination is Increased on Select Proteins in the Brainstem of the NADH dehydrogenase (ubiquinone) Fe-S protein 4 (Ndufs4) Knockout Mouse, a Model of Leigh Syndrome.
    Piroli GG; Manuel AM; Clapper AC; Walla MD; Baatz JE; Palmiter RD; Quintana A; Frizzell N
    Mol Cell Proteomics; 2016 Feb; 15(2):445-61. PubMed ID: 26450614
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Metabolic rescue ameliorates mitochondrial encephalo-cardiomyopathy in murine and human iPSC models of Leigh syndrome.
    Yoon JY; Daneshgar N; Chu Y; Chen B; Hefti M; Vikram A; Irani K; Song LS; Brenner C; Abel ED; London B; Dai DF
    Clin Transl Med; 2022 Jul; 12(7):e954. PubMed ID: 35872650
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Metallothionein 1 Overexpression Does Not Protect Against Mitochondrial Disease Pathology in Ndufs4 Knockout Mice.
    Miller HC; Louw R; Mereis M; Venter G; Boshoff JD; Mienie L; van Reenen M; Venter M; Lindeque JZ; Domínguez-Martínez A; Quintana A; van der Westhuizen FH
    Mol Neurobiol; 2021 Jan; 58(1):243-262. PubMed ID: 32918239
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ndufs4 KO mice: A model to study comorbid mood disorders associated with mitochondrial dysfunction.
    van Rensburg DJ; Lindeque Z; Harvey BH; Steyn SF
    Pharmacol Biochem Behav; 2024 Jan; 234():173689. PubMed ID: 38070656
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ndufs4 knockout mouse models of Leigh syndrome: pathophysiology and intervention.
    van de Wal MAE; Adjobo-Hermans MJW; Keijer J; Schirris TJJ; Homberg JR; Wieckowski MR; Grefte S; van Schothorst EM; van Karnebeek C; Quintana A; Koopman WJH
    Brain; 2022 Mar; 145(1):45-63. PubMed ID: 34849584
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Double administration of self-complementary AAV9NDUFS4 prevents Leigh disease in Ndufs4-/- mice.
    Corrà S; Cerutti R; Balmaceda V; Viscomi C; Zeviani M
    Brain; 2022 Oct; 145(10):3405-3414. PubMed ID: 36270002
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Iron status influences mitochondrial disease progression in Complex I-deficient mice.
    Kelly CJ; Couch RK; Ha VT; Bodart CM; Wu J; Huff S; Herrel NT; Kim HD; Zimmermann AO; Shattuck J; Pan YC; Kaeberlein M; Grillo AS
    Elife; 2023 Feb; 12():. PubMed ID: 36799301
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Elevated susceptibility to exogenous seizure triggers and impaired interneuron excitability in a mouse model of Leigh syndrome epilepsy.
    Manning A; Han V; Stephens A; Wang R; Bush N; Bard M; Ramirez JM; Kalume F
    Neurobiol Dis; 2023 Oct; 187():106288. PubMed ID: 37704057
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Interferon-gamma contributes to disease progression in the Ndufs4(-/-) model of Leigh syndrome.
    Hanaford AR; Khanna A; James K; Truong V; Liao R; Chen Y; Mulholland M; Kayser EB; Watanabe K; Hsieh ES; Sedensky M; Morgan PG; Kalia V; Sarkar S; Johnson SC
    Neuropathol Appl Neurobiol; 2024 Jun; 50(3):e12977. PubMed ID: 38680020
    [TBL] [Abstract][Full Text] [Related]  

  • 20.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 11.