BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

183 related articles for article (PubMed ID: 34795296)

  • 1. Crystal structures of the elusive Rhizobium etli L-asparaginase reveal a peculiar active site.
    Loch JI; Imiolczyk B; Sliwiak J; Wantuch A; Bejger M; Gilski M; Jaskolski M
    Nat Commun; 2021 Nov; 12(1):6717. PubMed ID: 34795296
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Rhizobium etli has two L-asparaginases with low sequence identity but similar structure and catalytic center.
    Loch JI; Worsztynowicz P; Sliwiak J; Grzechowiak M; Imiolczyk B; Pokrywka K; Chwastyk M; Gilski M; Jaskolski M
    Acta Crystallogr D Struct Biol; 2023 Aug; 79(Pt 8):775-791. PubMed ID: 37494066
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Biochemical characterization of recombinant L-asparaginase (AnsA) from Rhizobium etli, a member of an increasing rhizobial-type family of L-asparaginases.
    Moreno-Enriquez A; Evangelista-Martinez Z; Gonzalez-Mondragon EG; Calderon-Flores A; Arreguin R; Perez-Rueda E; Huerta-Saquero A
    J Microbiol Biotechnol; 2012 Mar; 22(3):292-300. PubMed ID: 22450783
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Probing the active site of Class 3 L-asparaginase by mutagenesis. I. Tinkering with the zinc coordination site of ReAV.
    Pokrywka K; Grzechowiak M; Sliwiak J; Worsztynowicz P; Loch JI; Ruszkowski M; Gilski M; Jaskolski M
    Front Chem; 2024; 12():1381032. PubMed ID: 38638878
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Interaction between the biotin carboxyl carrier domain and the biotin carboxylase domain in pyruvate carboxylase from Rhizobium etli.
    Lietzan AD; Menefee AL; Zeczycki TN; Kumar S; Attwood PV; Wallace JC; Cleland WW; St Maurice M
    Biochemistry; 2011 Nov; 50(45):9708-23. PubMed ID: 21958016
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Rhizobium etli asparaginase II: an alternative for acute lymphoblastic leukemia (ALL) treatment.
    Huerta-Saquero A; Evangelista-Martínez Z; Moreno-Enriquez A; Perez-Rueda E
    Bioengineered; 2013; 4(1):30-6. PubMed ID: 22895060
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Biochemical characterization of L-asparaginase isoforms from
    Sliwiak J; Worsztynowicz P; Pokrywka K; Loch JI; Grzechowiak M; Jaskolski M
    Front Chem; 2024; 12():1373312. PubMed ID: 38456185
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structures of l-asparaginase from
    Ran T; Jiao L; Wang W; Chen J; Chi H; Lu Z; Zhang C; Xu D; Lu F
    J Agric Food Chem; 2021 Jan; 69(1):223-231. PubMed ID: 33371681
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Improvement of the activity of l-asparaginase I improvement of the catalytic activity of l-asparaginase I from Bacillus megaterium H-1 by in vitro directed evolution.
    Lu X; Chen J; Jiao L; Zhong L; Lu Z; Zhang C; Lu F
    J Biosci Bioeng; 2019 Dec; 128(6):683-689. PubMed ID: 31326332
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Activation and inhibition of pyruvate carboxylase from Rhizobium etli.
    Zeczycki TN; Menefee AL; Jitrapakdee S; Wallace JC; Attwood PV; St Maurice M; Cleland WW
    Biochemistry; 2011 Nov; 50(45):9694-707. PubMed ID: 21958066
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Probing the catalytic roles of Arg548 and Gln552 in the carboxyl transferase domain of the Rhizobium etli pyruvate carboxylase by site-directed mutagenesis.
    Duangpan S; Jitrapakdee S; Adina-Zada A; Byrne L; Zeczycki TN; St Maurice M; Cleland WW; Wallace JC; Attwood PV
    Biochemistry; 2010 Apr; 49(15):3296-304. PubMed ID: 20230056
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Investigation of the Roles of Allosteric Domain Arginine, Aspartate, and Glutamate Residues of Rhizobium etli Pyruvate Carboxylase in Relation to Its Activation by Acetyl CoA.
    Sirithanakorn C; Jitrapakdee S; Attwood PV
    Biochemistry; 2016 Aug; 55(30):4220-8. PubMed ID: 27379711
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tackling Critical Catalytic Residues in Helicobacter pylori L-Asparaginase.
    Maggi M; Chiarelli LR; Valentini G; Scotti C
    Biomolecules; 2015 Mar; 5(2):306-17. PubMed ID: 25826146
    [TBL] [Abstract][Full Text] [Related]  

  • 14. [PEG-chitosan branched copolymers to improve the biocatalytic properties of Erwinia carotovora recombinant L-asparaginase].
    Kudryashova EV; Suhoverkov KV; Sokolov NN
    Biomed Khim; 2015; 61(4):480-7. PubMed ID: 26350739
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A covalently bound catalytic intermediate in Escherichia coli asparaginase: crystal structure of a Thr-89-Val mutant.
    Palm GJ; Lubkowski J; Derst C; Schleper S; Röhm KH; Wlodawer A
    FEBS Lett; 1996 Jul; 390(2):211-6. PubMed ID: 8706862
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Geometric considerations support the double-displacement catalytic mechanism of l-asparaginase.
    Lubkowski J; Wlodawer A
    Protein Sci; 2019 Oct; 28(10):1850-1864. PubMed ID: 31423681
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural and functional role of Gly281 in L-asparaginase from Erwinia carotovora.
    Kotzia GA; Labrou NE
    Protein Pept Lett; 2013 Dec; 20(12):1302-7. PubMed ID: 24261975
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Crystal structure of active site mutant of antileukemic L-asparaginase reveals conserved zinc-binding site.
    Borek D; Kozak M; Pei J; Jaskolski M
    FEBS J; 2014 Sep; 281(18):4097-111. PubMed ID: 25040257
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Do bacterial L-asparaginases utilize a catalytic triad Thr-Tyr-Glu?
    Aghaiypour K; Wlodawer A; Lubkowski J
    Biochim Biophys Acta; 2001 Dec; 1550(2):117-28. PubMed ID: 11755201
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Elucidation of the specific function of the conserved threonine triad responsible for human L-asparaginase autocleavage and substrate hydrolysis.
    Nomme J; Su Y; Lavie A
    J Mol Biol; 2014 Jun; 426(13):2471-85. PubMed ID: 24768817
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.